Qhov sib txawv tseem ceeb ntawm pepsin thiab renin yog pepsin, uas yog ib qho ntawm cov plab hnyuv siab raum, yog ib qho protease secreted los ntawm lub plab thaum renin yog ib qho enzyme thiab kuj yog ib yam tshuaj uas tsim los ntawm juxtaglomerular hlwb ntawm lub raum.
Proteases yog cov enzymes uas hydrolyze peptide bonds thiab zom cov proteins rau hauv peptides lossis amino acids. Pepsin yog ib qho protease muaj nyob rau hauv cov kua txiv hmab txiv ntoo. Nws yog ib qho ntawm lub ntsiab digestive enzymes uas zom cov zaub mov proteinaceous rau peptides thiab amino acids. Piv txwv li, renin yog ib qho enzyme thiab aspartic protease. Nws yog qhov pib enzyme ntawm renin-angiotensin system. Renin ua haujlwm raws li cov tshuaj hormones thiab pab tswj cov ntshav siab.
YPepsin yog dab tsi?
Pepsin yog qhov ua tau zoo ntawm cov enzymes. Nws yog lub ntsiab enzyme tam sim no nyob rau hauv lub plab kua txiv. Theodor Schwann nrhiav tau nws nyob rau hauv 1836. Pepsin muaj peb-dimensional qauv. Nws hydrolyzes peptide bonds ntawm hydrophobic thiab aromatic amino acids xws li phenylalanine, tryptophan, thiab tyrosine, thiab lwm yam Pepsin muaj ib pawg catalytic aspartic hauv nws qhov chaw nquag. Pepsinogen yog daim ntawv tsis ua haujlwm ntawm pepsin.
Daim duab 01: Pepsin
Stomach HCl hloov pepsinogen mus rau pepsin nquag. Nyob rau hauv ib puag ncig acidic hauv plab, pepsin cleaves proteins rau hauv peptides lossis amino acids. Cov kab mob alkaline siab thiab qee yam inhibitors xws li pepstatin, sucralfate, thiab lwm yam tuaj yeem thaiv pepsin enzyme tau zoo.
Renin yog dab tsi?
Renin yog ib qho enzyme secreted los ntawm cov hlwb tshwj xeeb hauv ob lub raum. Nws yog aspartic protease. Robert Tigerstedt thiab Per Bergman pom renin thawj zaug.
Daim duab 02: Renin
Nws pab tswj cov ntshav siab los ntawm kev ua raws li cov tshuaj hormones thiab. Thaum cov ntshav siab poob qis, renin tuaj rau hauv cov hlab ntsha thiab ua rau kev hloov pauv ntawm angiotensinogen rau angiotensin I. Angiotensin-hloov enzyme catalyzes hloov pauv ntawm angiotensin I mus rau angiotensin II. Angiotensin II constricts cov hlab ntsha kom ntshav siab. Tsis tas li ntawd, angiotensin II txhawb cov qog adrenal los tsim aldosterone. Aldosterone hormone nce qib ntsev hauv cov ntshav, yog li ua kom ntshav siab.
Dab tsi zoo sib xws ntawm Pepsin thiab Renin?
- Pepsin thiab renin yog ob lub proteases.
- Ntxiv mus, ob qho tib si yog aspartic protease
Qhov txawv ntawm Pepsin thiab Renin yog dab tsi?
Pepsin thiab renin yog proteases uas rhuav cov proteins rau hauv cov molecules yooj yim. Pepsin yog lub hauv paus digestive protease hauv plab. Hauv qhov sib piv, renin yog qhov pib enzyme ntawm renin-angiotensin system uas pab tswj ntshav siab. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm pepsin thiab renin. Lub plab secretes pepsin thaum juxtaglomerular hlwb ntawm lub raum tsim renin. Lwm qhov sib txawv ntawm pepsin thiab renin yog renin ua raws li cov tshuaj hormones uas pab tswj cov ntshav siab thaum pepsin tsis ua raws li cov tshuaj hormones.
Cov lus qhia hauv qab no qhia txog qhov sib txawv ntawm pepsin thiab renin.
Summary – Pepsin vs Renin
Pepsin yog lub hauv paus acid protease ntawm lub plab. Hauv qhov sib piv, renin yog qhov pib enzyme ntawm renin-angiotensin system. Cov hlwb tshwj xeeb hauv lub raum zais renin rau hauv cov hlab ntsha. Pepsin rhuav tshem cov zaub mov proteinaceous rau hauv cov amino acids thaum renin pab tswj cov ntshav siab los ntawm cleaving angiotensinogen rau hauv angiotensin I. Yog li, qhov no qhia txog qhov txawv ntawm pepsin thiab renin.
