Qhov Tseem Ceeb Qhov txawv - Qhov Zoo vs Qhov Tsis Txaus Siab RNA Virus
qhov kev nkag siab zoo thiab qhov tsis zoo DNA xa mus rau coding sequence thiab non-coding sequence (template) feem. Yog hais tias DNA ib ntus ncaj qha muab tib lub mRNA ib ntus los ntawm cov ntawv sau, nws yog lub npe hu ua kev nkag siab zoo lossis kev nkag siab DNA. Yog hais tias DNA ib ntus ua tiav mRNA ib ntus los ntawm kev sau ntawv, nws yog lub npe hu ua qhov tsis zoo los yog antisense DNA. Nyob rau hauv kev hwm rau virology, genome ntawm tus kab mob RNA raug xa mus rau qhov zoo lossis qhov tsis zoo. Kev nkag siab zoo RNA tus kab mob muaj ib leeg-stranded RNA genome uas tuaj yeem ua haujlwm raws li mRNA ib ntus thiab txhais ncaj qha los tsim cov amino acid sib lawv liag. Kev nkag siab tsis zoo RNA tus kab mob muaj ib leeg-stranded RNA genome uas tsim cov mRNA sib txuas los ntawm cov ntawv sau. Qhov no yog qhov txawv ntawm qhov zoo thiab qhov tsis zoo ntawm tus kab mob RNA.
Tus kab mob zoo RNA yog dab tsi?
Kev nkag siab zoo RNA tus kab mob yog ib hom kab mob uas muaj kev nkag siab zoo ib leeg RNA raws li nws cov khoom siv caj ces. Cov kab mob no muaj peev xwm ua haujlwm raws li tus tub txib RNA thiab muaj peev xwm muab txhais ncaj qha rau hauv cov protein hauv tus tswv tsev. Raws li B altimore cov txheej txheem kev faib tawm, kev nkag siab zoo ib leeg-stranded RNA tus kab mob belongs rau pawg IV. Cov kab mob RNA no yog lub luag haujlwm rau feem ntau ntawm cov kab mob RNA suav nrog tus kab mob siab C, tus kab mob West Nile thiab tus kab mob dengue thiab cov kab mob ua lub luag haujlwm rau SARS thiab MERS. Lawv kuj suav nrog hauv qeb uas ua rau mob me me xws li mob khaub thuas.
Vim tias kev nkag siab zoo RNA tus kab mob genomes muaj peev xwm ua tus xa xov RNA, lawv cov genomes ncaj qha txhais ua cov proteins los ntawm tus tswv ribosomes. Thaum cov kab mob kis tau tsim tawm hauv tus tswv tsev, lawv nrhiav RNA los tsim cov kab mob sib kis. Viral replication txuas ntxiv los ntawm ob-stranded RNA intermediates.
Daim duab 01: Tus Kab Mob Zoo RNA - Kab Mob Siab C
Kev koom tes ntawm ob-txoj RNA muab lub sijhawm rau tus kabmob txhawm rau txhawm rau tiv thaiv kab mob. Tag nrho cov kab mob no encode cov synthesis ntawm ib hom RNA protein hu ua RNA dependent polymerase. Hauv cov xwm txheej no, RNA yog tsim los ntawm RNA template. Muaj ob peb hom ntawm tus tswv tsev cell proteins uas tau txais los ntawm cov kev nkag siab zoo no ib leeg-stranded RNA tus kab mob. Cov no suav nrog RNA binding proteins, membrane remodeling proteins, chaperone proteins. Tag nrho cov proteins no koom nrog hauv kev siv cov tswv tsev cell secretary pathways xav tau rau kis kab mob.
Tus kab mob tsis zoo RNA yog dab tsi?
Nyob rau hauv cov ntsiab lus ntawm qhov tsis zoo ntawm tus kab mob RNA, cov khoom siv caj ces uas muaj nyob hauv tus kab mob no muab ntxiv rau mRNA ib ntus tom qab kev sau ntawv. Yog li, lawv raug xa mus rau qhov tsis zoo-xav ib leeg-stranded RNA virus lossis Antisense RNA viruses. Kev nkag siab tsis zoo ib leeg-stranded RNA tus kab mob muaj cov kab mob genomic nyuaj. Tsis tas li ntawd, nws muaj cov txheej txheem rov ua dua tshiab thiab lub voj voog ntawm tes. Qhov tseeb tseem ceeb ntawm kev nkag siab tsis zoo ib leeg-stranded RNA tus kab mob siv cov protein ntau sib txawv hauv kev sib txawv ntawm kev sib txawv txhawm rau ua cov txheej txheem sib txawv hauv cov ntsiab lus ntawm kev rov ua dua ntawm RNA genomic sequences thiab ciaj sia taus ntawm tus kab mob.
Daim duab 02: Tsis zoo RNA Virus
Raws li tau hais los saum toj no, qhov tsis zoo-kev hnov lus ib leeg-tso RNA tus kab mob muaj qhov xwm txheej nyuaj thiab yog li lawv muaj peev xwm tiv thaiv kev tiv thaiv kab mob los ntawm kev tawm tsam ntawm innate kev tiv thaiv. Yog li, nws tuaj yeem kis tau cov hlwb thiab koom nrog hauv kev tsim kho ntawm capsids uas yog qhov tshwj xeeb rau txhua yam ntawm cov kab mob tsis zoo ib leeg-stranded RNA. Cov kab mob RNA no xav tau RNA polymerase txhawm rau tsim kom muaj kev nkag siab zoo RNA. Piv txwv ntawm qhov tsis zoo ntawm tus kab mob RNA ib leeg yog kab mob khaub thuas, kab mob qhua pias thiab tus kab mob rabies.
Dab tsi yog qhov zoo sib xws ntawm qhov zoo thiab qhov tsis zoo RNA tus kab mob?
- Ob Qhov Zoo thiab Tsis Txaus Siab RNA Virus yog RNA viruses.
- Ob Qhov Zoo thiab Tsis Txaus Siab RNA Virus muaj peev xwm nkag mus rau cov tswv tsev thiab ua rau muaj kev puas tsuaj.
Qhov txawv ntawm qhov zoo thiab qhov tsis zoo RNA Virus yog dab tsi?
Zoo vs Negative Sense RNA Virus |
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| tus kab mob RNA zoo muaj ib leeg-stranded RNA raws li lawv cov khoom siv caj ces tuaj yeem ua haujlwm ncaj qha li mRNA. | Tus kab mob tsis zoo RNA muaj ib qho RNA tso tseg raws li lawv cov khoom siv caj ces uas ua rau muaj qhov sib ntxiv ntawm mRNA. |
| Production of Positive Sense RNA | |
| Kev nkag siab zoo RNA tus kab mob genome ua haujlwm raws li mRNA ncaj qha thaum tsim cov proteins. | Negative Sense RNA tus kab mob genome yuav tsum tsim kom muaj kev nkag siab zoo mRNA ib ntus los ntawm nws cov genome siv RNA polymerases. |
| Examples | |
| Tus kab mob siab C, tus kab mob West Nile, tus kab mob dengue thiab cov kab mob ua rau SARS thiab MERS yog cov piv txwv ntawm cov kab mob RNA zoo. | Tus kab mob khaub thuas, kab mob qhua pias thiab kab mob rabies yog cov piv txwv rau cov kab mob RNA tsis zoo. |
Summary – Positive vs Negative Sense RNA Virus
Kev nkag siab zoo RNA tus kab mob yog ib hom kab mob uas muaj kev nkag siab zoo ib leeg RNA raws li nws cov khoom siv caj ces. Lawv kuj muaj peev xwm ua haujlwm raws li tus tub txib RNA thiab muaj peev xwm muab txhais ncaj qha rau hauv cov protein los ntawm tus tswv tsev ribosomes. Hauv kev nkag siab tsis zoo RNA tus kab mob, cov khoom siv caj ces uas tam sim no tsis tuaj yeem ua haujlwm raws li mRNA ib ntus. Lawv yuav tsum tsim kom muaj kev nkag siab zoo mRNA los ntawm kev sib txuas RNA uas tuaj yeem tsim los ntawm genome. Cov kab mob no yog qhov nyuaj heev, thiab yog li lawv muaj peev xwm tiv thaiv kev tiv thaiv kab mob los ntawm kev tawm tsam ntawm innate kev tiv thaiv ntawm tus tswv tsev. Qhov no yog qhov txawv ntawm qhov zoo thiab qhov tsis zoo ntawm tus kab mob RNA.
Download the PDF of Positive vs Negative Sense RNA Virus
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li daim ntawv ceeb toom. Thov rub tawm PDF version ntawm no: Qhov txawv ntawm qhov zoo thiab qhov tsis zoo ntawm RNA Virus
