Qhov sib txawv tseem ceeb ntawm dynein thiab kinesin yog tias dynein yog cytoskeleton motor protein uas txav mus rau qhov kawg ntawm microtubules thaum kinesin yog lwm cytoskeleton motor protein uas txav mus rau qhov kawg ntawm microtubules.
Lub cytoskeleton muaj ntau hom filaments. Microtubules yog ib hom ntawm lawv. Lawv coj cov khoom txav hauv lub cell. Lawv kuj tseem ceeb hauv kev tswj xyuas cov duab ntawm tes. Tsis tas li ntawd, microtubules yog qhov tseem ceeb hauv kev sib cais chromosomes hauv mitosis thiab meiosis. Tsis tas li ntawd, microtubules yog cov khoom tseem ceeb ntawm cilia thiab flagella ntawm qee lub hlwb eukaryotic. Structurally, microtubules yog polar lug. Lawv muaj qhov xaus ntxiv thiab rho tawm kawg. Feem ntau, qhov kawg rho tawm mus rau qhov chaw ntawm lub xov tooj thaum lub ntxiv kawg txuas mus rau ntawm lub xov tooj ntawm tes. Thaum lub sij hawm thauj intracellular ntawm vesicles thiab organelles, ob hom cytoskeleton motor proteins pab microtubules. Lawv yog cov dyneins thiab kinesins. Dyneins txav mus rau qhov kawg ntawm lub microtubules thaum nqa cov ntaub ntawv mus rau qhov chaw ntawm lub cell. Hauv qhov sib piv, kinesins taug kev ntawm lub xov tooj ntawm tes nqa cov khoom mus rau qhov chaw ntawm lub xov tooj.
Dynein yog dab tsi?
Dynein yog lub cev muaj zog muaj protein nyob hauv cytoskeleton ntawm cov hlwb. Lawv muaj peev xwm txav mus raws microtubules thiab pab txoj kev thauj mus los ntawm cov hlab ntsha thiab cov organelles. Dynein mus rau qhov kawg ntawm lub microtubules. Thaum mus ncig, lawv nqa cov ntaub ntawv mus rau qhov chaw ntawm lub xovtooj vim tias qhov kawg ntawm qhov rho tawm mus rau qhov chaw ntawm lub xovtooj.
Daim duab 01: Dynein
Hauv cov lus yooj yim, dyneins yog cov cytoskeleton lub cev muaj zog cov proteins uas thauj cov khoom thauj (organelles thiab vesicles) los ntawm qhov nruab nrab ntawm lub xov tooj ntawm tes mus rau qhov chaw (retrograde thauj). Tsis tas li ntawd xwb, dynein yog ib qho tseem ceeb ntawm cilia thiab flagella uas yog ib qho tseem ceeb hauv zawv zawg microtubules txheeb ze rau ib leeg. Li no, lawv yog ib qho tseem ceeb nyob rau hauv kev ntaus ntawm cilia thiab flagella nyob rau saum npoo ntawm ib co eukaryotic hlwb.
Kinesin yog dab tsi?
Kinesin yog lwm hom cytoskeleton lub cev muaj zog cov protein uas muaj peev xwm txav mus raws microtubules filaments. Ntxiv mus, kinesins yog ATPases. Lawv cov kev txav yog siv zog. Feem ntau cov kinesins taug kev mus rau qhov kawg ntawm cov microtubules uas muaj nyob rau ntawm qhov chaw ntawm lub xovtooj (mus rau ntawm lub xovtooj ntawm tes). Thaum mus ncig, kinesins nqa cov khoom thauj (organelles thiab vesicles) los ntawm qhov chaw ntawm lub cell mus rau qhov chaw ntawm lub cell (anterograde thauj).
Daim duab 02: Kinesin
Kev hloov pauv ntawm kinesin proteins tuaj yeem ua rau lub paj hlwb tsis zoo. Ib yam kab mob zoo li no yog peripheral neuropathy.
Dynein thiab Kinesin zoo sib xws yog dab tsi?
- Dynein thiab kinesin yog ob lub cev muaj zog.
- Lawv yog cov molecules tseem ceeb ntawm cytoskeleton.
- Ob leeg dynein thiab kinesin txav raws cov microtubules.
- Ntxiv mus, lawv pab thauj khoom hauv lub cell.
- Tsis tas li, ob qho proteins tseem ceeb hauv kev faib cell.
- qauv, ob qho tib si cov proteins yog ATP hydrolases.
Qhov txawv ntawm Dynein thiab Kinesin yog dab tsi?
Qhov sib txawv tseem ceeb ntawm dynein thiab kinesin yog cov kev taw qhia ntawm lawv txoj kev txav mus rau microtubules. Dynein txav mus rau qhov kawg ntawm lub microtubule thaum kinesin txav mus rau qhov kawg ntawm microtubule. Ntxiv mus, dynein thauj cov khoom thauj los ntawm lub periphery mus rau qhov chaw ntawm lub cell thaum kinesin thauj cov khoom thauj los ntawm qhov chaw mus rau qhov chaw ntawm lub cell. Yog li, qhov no yog qhov tseem ceeb ua haujlwm sib txawv ntawm dynein thiab kinesin. Structurally, dynein protein muaj ib mus rau peb hnyav chains complex mus rau nruab nrab, lub teeb-intermediate thiab lub teeb chains. Ntawm qhov tod tes, kinesin protein muaj ob lub chains hnyav thiab ob lub teeb chains. Yog li, qhov no yog lwm qhov sib txawv ntawm dynein thiab kinesin.
Summary – Dynein vs Kinesin
Dynein thiab kinesin yog ob lub cev muaj zog tseem ceeb muaj nyob hauv cytoskeleton. Lawv txav mus raws microtubules thiab pab txhawb kev thauj mus los ntawm cov hlwv thiab organelles. Qhov sib txawv tseem ceeb ntawm dynein thiab kinesin yog cov kev taw qhia ntawm kev txav. Dynein txav mus rau qhov kawg ntawm lub microtubule thaum kinesin txav mus rau qhov kawg ntawm microtubule. Tsis tas li ntawd, dynein thauj cov khoom thauj mus rau qhov chaw ntawm lub cell thaum kinesin thauj cov khoom thauj mus rau qhov chaw ntawm lub cell. Ob leeg cov proteins no yog ATP hydrolases. Ntxiv mus, ob qho tib si cov proteins no tseem ceeb rau kev faib cov cell. Tsis tas li ntawd, dyneins tseem ceeb hauv kev ntaus ntawm cilia thiab flagella ntawm qee lub hlwb eukaryotic. Yog li, qhov no qhia txog qhov sib txawv ntawm dynein thiab kinesin.