Qhov sib txawv tseem ceeb ntawm osteoblasts thiab osteoclasts yog tias osteoblasts yog ib hom pob txha hlwb uas tsim cov pob txha tshiab thaum osteoclasts yog lwm hom pob txha uas yaj cov pob txha.
Cov pob txha yog ib feem ntawm peb lub cev pob txha. Nws yog ib qho tawv, tab sis resilient cov ntaub so ntswg uas yog tshwj xeeb rau vertebrates. Lub luag haujlwm tseem ceeb ntawm cov pob txha yog los tiv thaiv cov kab mob hauv nruab nrog cev thiab muab kev txhawb nqa nruj rau cov leeg nqaij. Muaj peb hom hlwb hauv cov pob txha: osteoblasts, osteoclasts, thiab osteocytes. Osteocytes yog cov laus osteoblasts, thiab lawv tsis tso cov pob txha matrix. Ntxiv mus, lub luag haujlwm ntawm osteocyte yog tswj cov metabolism thiab pauv cov as-ham thiab tshem tawm cov khib nyiab. Osteoblasts yog cov pob txha tsim cov hlwb thaum osteoclasts muaj qhov cuam tshuam ntawm osteoblasts, uas yog pob txha resorption. Li no, ob hom cell no tswj tus nqi ntawm kev tsim thiab tawg ntawm cov pob txha lossis pob txha kho.
Osteoblasts yog dab tsi?
Osteoblasts yog me me, mononucleate hlwb uas yog lub luag haujlwm rau kev tsim cov pob txha. Lawv muaj peev xwm los tsim cov collagen matrix, qhov twg mineralization tshwm sim. Tsis tas li ntawd, cov hlwb no tseem ceeb rau kev saib xyuas, kev loj hlob, thiab kho cov pob txha. Hauv cov pob txha, tsuas yog osteoblasts muaj cov tshuaj parathyroid hormone (PTH) receptors.
Daim duab 01: Pob txha pob txha
Thaum osteoblasts tau qhib los ntawm PTH, osteoblasts tso tawm cytokines uas ncaj qha thiab tsis ncaj qha rau osteoblasts, uas thaum kawg nce tus naj npawb thiab kev ua haujlwm ntawm osteoclasts. Lub hauv paus chiv keeb ntawm osteoblasts yog osteoprogenitor hlwb nyob rau hauv lub periosteum thiab pob txha pob txha.
Osteoclasts yog dab tsi?
Osteoclasts yog lwm hom pob txha hlwb uas loj thiab muaj qee qhov tshwj xeeb ntawm cov txheej txheem ultrastructure xws li ntau lub nuclei, mitochondria ntau thiab ntau cov vacuoles thiab lysosomes. Tsis tas li ntawd, lub xub ntiag ntawm qhov chaw sib khi thiab ruffled ciam teb yog ib yam ntxwv ntawm osteoclasts.
Daim duab 02: Osteoclasts
Lub luag haujlwm tseem ceeb ntawm osteoclasts yog qhov resorption thiab degradation ntawm pob txha; yog li ntawd, lawv pab kho cov pob txha thaum rhuav tshem cov pob txha thiab rov nqus calcium. Tsis tas li ntawd, osteoclasts pab tswj cov ntshav calcium concentration ntawm qib zoo. Hauv cov txheej txheem kho pob txha, osteoblasts kho cov kev ua ntawm osteoclasts los ntawm cytokines.
Dab tsi yog qhov zoo sib xws ntawm Osteoblasts thiab Osteoclasts?
- Osteoblasts thiab osteoclasts yog ob hom pob txha hlwb.
- Lawv tuaj ntawm cov pob txha.
- Tsis tas li ntawd, lawv pom nyob saum cov pob txha.
- Kuj, ob leeg koom nrog kev kho pob txha.
Qhov txawv ntawm Osteoblasts thiab Osteoclasts yog dab tsi?
Osteoblasts yog hom pob txha pob txha uas tsim cov pob txha tshiab thaum osteoclasts yog hom pob txha pob txha uas yaj cov pob txha. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm osteoblasts thiab osteoclasts. Ntxiv rau qhov no, qhov sib txawv tseem ceeb ntawm osteoblasts thiab osteoclasts yog cov progenitors ntawm osteoblasts tau muab los ntawm pluripotent mesenchymal qia hlwb thaum cov osteoclasts tau muab los ntawm cov hlwb hematopoietic ntawm granulocyte-macrophage kab.
Ntxiv mus, osteoblasts kho cov dej num ntawm osteoclasts los ntawm kev tso cytokines. Tsis tas li ntawd, osteoblasts muaj receptors rau parathyroid hormone (PTH) tab sis tsis yog osteoclasts. Yog li, peb tuaj yeem xav txog qhov no kuj yog qhov sib txawv ntawm osteoblasts thiab osteoclasts. Tsis tas li ntawd, qhov tseem ceeb sib txawv ntawm osteoblasts thiab osteoclasts yog tias cov osteoblasts txhawb kev tsim cov pob txha thaum osteoclasts txhawb cov pob txha tawg.
Ntxiv rau, osteoblasts dhau los ua osteocytes thaum osteoclasts tsis ua. Tsis tas li ntawd, lwm qhov sib txawv ntawm osteoblasts thiab osteoclasts yog cov osteoblasts me dua thiab mononucleate whereas osteoclasts loj dua thiab multinucleate.
Hauv qab infographic qhia txog qhov sib txawv ntawm osteoblasts thiab osteoclasts, sib piv.
Summary – Osteoblasts vs Osteoclasts
Ntawm peb hom pob txha, osteoblasts thiab osteoclasts yog ob hom uas tseem ceeb hauv kev kho pob txha. Osteoblasts yog me me mononucleated hlwb uas tsim cov pob txha tshiab thaum osteoclasts yog cov cell loj multinucleated uas yaj cov pob txha. Osteoblasts tuaj yeem dhau los ua osteocytes, thib peb ntawm cov pob txha hlwb, thaum osteoclasts tsis tuaj yeem. Tsis tas li ntawd, osteoblasts tuaj yeem kho cov haujlwm ntawm osteoclasts, tso cytokines. Yog li, qhov no yog cov ntsiab lus ntawm qhov sib txawv ntawm osteoblasts thiab osteoclasts.
