Qhov sib txawv tseem ceeb ntawm interferon alpha 2A thiab 2B yog tias hauv interferon alpha 2A, kev kho mob tsis nyob ntawm qhov hnyav ntawm tus neeg thaum kev kho mob ntawm interferon alpha 2B nyob ntawm qhov hnyav ntawm tus neeg.
Interferons yog cov proteins uas muaj peev xwm paub txog cov kab mob thiab rhuav tshem lawv. Lawv ib txwm muaj nyob hauv peb lub cev. Vim qhov nce ntawm cov kab mob kis, kev tsim khoom ntawm interferons tau nce, thiab nws ua haujlwm nrog kev siv cov thev naus laus zis DNA recombinant. Cov hom interferons no tau siv ntau heev los ua kev kho mob tiv thaiv kab mob. Interferon alpha 2A thiab interferon alpha 2B yog ob hom recombinant ntau yam ntawm cov lag luam muaj interferons. Txawm li cas los xij, muaj qhov sib txawv ntawm interferon alpha 2A thiab 2B raws li kev kho mob ntawm txhua tus interferons.
Interferon Alpha 2A yog dab tsi?
Interferon alpha 2A yog recombinant tib neeg interferon. Qhov no zoo ib yam li interferon tsim los ntawm tib neeg leukocyte. Cov khoom lag luam muaj interferon alpha 2A yog ib qho pegylated. Nyob rau hauv tus txheej txheem ntawm pegylation, interferon alpha 2A conjugates nrog polyethene glycol uas ua rau kom lub sij hawm uas cov tshuaj nyob twj ywm nyob rau hauv lub cev. Lub interferon alpha 2A khi rau interferon receptor molecule los qhib MHC chav kawm I molecules tawm tsam tus kab mob.
Daim duab 01: Interferon Alpha 2 Protein
koob tshuaj interferon alpha 2A kev kho mob yog nyob ntawm cov kab mob sib txawv. Tsis tas li ntawd, interferon alpha 2A kev kho mob ua haujlwm txhua lub lim tiam. Txawm li cas los xij, hauv txoj kev kho mob, qhov hnyav ntawm tus neeg mob tsis xav txog vim nws tsis siv. Vim muaj kev cuam tshuam mus ntev rau interferon alpha 2A, cov kev mob tshwm sim hauv qab no yuav raug pom xws li anemia, kab mob autoimmune, cardiotoxicity, hepatotoxicity thiab peripheral neuropathy, thiab lwm yam.
Interferon Alpha 2B yog dab tsi?
Interferon alpha 2B yog lwm hom recombinant interferon. Thaum interferon alpha 2B ua rau tus kab mob, nws ua rau lub cev tiv thaiv kab mob tawm tsam tus kab mob. Cov ntau yam recombinant ua raws li lub ntuj interferons tsim los ntawm leukocytes. Qhov xwm ntawm interferon alpha 2B zoo ib yam li interferon alpha 2A.
Daim duab 02: Interferon Alpha 2B
Txawm li cas los xij, qhov sib txawv ntawm interferon alpha 2A thiab 2B yog nyob ntawm txoj kev kho mob. Thaum muab tshuaj rau kev kho mob ntawm interferon alpha 2B, qhov hnyav ntawm tus neeg mob raug txiav txim siab. Kev noj ntau npaum thiab qhov ntev ntawm kev kho mob yog nyob ntawm qhov hnyav ntawm tus neeg. Yog li, kev kho interferon alpha 2B yog qhov tshwj xeeb tshaj li qhov interferon alpha 2A. Ntxiv mus, cov kev mob tshwm sim ntawm interferon alpha 2B kev kho mob suav nrog hepatotoxicity, cardiotoxicity thiab kab mob autoimmune.
Dab tsi yog qhov zoo sib xws ntawm Interferon Alpha 2A thiab 2B?
- Interferon Alpha 2A thiab 2B yog recombinant ntau yam ntawm tib neeg interferon.
- Kuj, ob leeg tuaj yeem pegylated.
- Tsis tas li ntawd, lawv ua rau cov kab mob hauv peb lub cev, yog li ntawd, ob qho tib si siv los kho cov kab mob kis.
- Ntxiv mus, ob qho kev kho mob no qhib MHC chav kawm kuv cov molecules los tawm tsam cov kab mob.
- Tsis tas li, lawv ua raws li cov tshuaj interferons.
- Dhau li ntawd, cov kev mob tshwm sim ntawm ob yam tshuaj muaj xws li hepatotoxicity, kab mob autoimmune thiab cardiotoxicity.
Qhov txawv ntawm Interferon Alpha 2A thiab 2B yog dab tsi?
Interferon alpha 2A yog ib qho kev sib txuas ntawm ntau yam interferons, uas yog kev kho mob tiv thaiv kab mob. Ntawm qhov tsis sib xws, txawm hais tias interferon alpha 2B kuj yog ib qho kev sib txuas ntawm ntau yam interferons, kev kho mob tiv thaiv kab mob yog nyob ntawm qhov hnyav ntawm tus neeg mob. Yog li, txoj kev kho mob ntawm alpha 2A tsis yog nyob ntawm qhov hnyav ntawm tus neeg thaum nws yog raws li qhov hnyav ntawm tus neeg hauv alpha 2B. Qhov no yog qhov sib txawv tseem ceeb ntawm Interferon alpha 2A thiab 2B. Ntxiv mus, lwm qhov sib txawv ntawm Interferon alpha 2A thiab 2B yog tias lub sijhawm ntawm alpha 2A yog ib lub lis piam thaum nws txawv hauv alpha 2B.
Cov ntawv qhia hauv qab no nthuav tawm qhov sib txawv ntawm Interferon alpha 2A thiab 2B hauv daim ntawv teev npe.
Summary – Interferon Alpha 2A vs 2B
Vim kev nce qib ntawm biotechnology, recombinant ntau yam ntawm kev kho mob tshwm sim. Interferon alpha 2A thiab 2B yog recombinant ntau yam ntawm tib neeg interferons uas yog siv rau kev kho mob rau tus kab mob. Yog li, qhov sib txawv tseem ceeb ntawm Interferon alpha 2A thiab 2B feem ntau yog nyob ntawm txoj kev kho mob. Kev kho Interferon alpha 2A tsis xav txog qhov hnyav ntawm tus neeg mob. Hauv qhov sib piv, kev kho mob interferon alpha 2B txiav txim siab qhov hnyav ntawm tus neeg mob. Txawm li cas los xij, feem ntau, ob qho tib si interferons yog pegylated kom ua tau zoo ntawm kev kho mob.
