Qhov Tseem Ceeb Qhov txawv - Glycerophospholipids vs Sphingolipids
Glycerophospholipids thiab sphingolipids yog cov tseem ceeb ntawm cov cell membrane. Cov glycerophospholipids muaj peb cov pa roj carbon glycerol qaum thaum lub sphingolipids muaj cov organic aliphatic amino cawv sphingosine. Qhov no yog qhov sib txawv tseem ceeb ntawm glycerophospholipids thiab sphingolipids. Ob leeg yog cov tseem ceeb ntawm cov cell membrane uas muaj cov khoom zoo sib xws.
Cell daim nyias nyias yog suav tias yog cov qauv tseem ceeb rau lub xovtooj ntawm tes vim lawv koom nrog ntau lub zog thaum lub sijhawm sib txawv ntawm tes. Lawv koom nrog kev tswj hwm ntawm kev sib pauv ntawm cov ntaub ntawv ntawm lub xovtooj ntawm tes thiab ib puag ncig sab nraud thiab tseem ua haujlwm hauv cov txheej txheem xovtooj ntawm tes uas ua rau cov hlwb sib txuas lus nrog cov hlwb nyob ib puag ncig. Cov cell membranes yog tsim los ntawm cov khoom tseem ceeb sib txawv.
YGlycerophospholipids yog dab tsi?
Glycerophospholipds yog suav tias yog cov khoom tseem ceeb ntawm daim nyias nyias los yog cov lipid bilayer. Lawv kuj tseem hu ua phosphoglycerides. Glycerophospholipds muaj peb pawg tseem ceeb hauv cov molecule nws tus kheej. Lawv yog peb cov pa roj carbon glycerol rov qab cov pob txha, ob txoj hlua ntev ntawm fatty acids uas yog esterified rau thawj thiab thib ob carbon atoms (C1 thiab C2 carbons) ntawm glycerol qaum qaum thiab phosphoric acid uas yog esterified rau hauv cov carbon atom kawg; carbon 3 (C3) hydroxyl pawg ntawm glycerol.
Feem ntau glycerophospholipds muaj lub taub hau cawv uas yog esterified rau phosphate. Glycerophospholipds thiab fatty acids yog suav tias yog amphiphilic molecules vim lawv muaj ob qho tib si hydrophilic thiab hydrophobic qhov chaw. Cov aliphatic chains ntawm fatty acids yog suav hais tias yog hydrophobic. Fatty acids 'carboxyl pawg thiab lub taub hau ntawm glycerophospholipds yog suav tias yog hydrophilic. Lub hydrophobic xwm ntawm glycerophospholipds tsav cov molecule no nyob rau hauv lub assembling ntawm lipid bilayers.
Cov hlwb hauv lub cev ua ke sib txawv ntawm cov glycerophospholipds loj nrog kev siv cov roj fatty acids sib txawv thiab los ntawm esterification ntawm ib qho ntawm tsib yam cawv sib txawv rau pawg phosphate. Hauv ib qho glycerophospholipid, thawj cov pa roj carbon monoxide muaj ob daim ntawv cog lus lossis tsis muaj ob daim ntawv cog lus thiab cov pa roj carbon thib ob muaj ob lossis ntau dua ob daim ntawv cog lus. Cov ob daim ntawv cog lus no tsim kev khoov mus tas li hauv cov saw hlau hydrocarbon. Qhov khoov mus tas li no muab qhov tsim nyog fluidity rau lub bilayer.
Daim duab 01: Glycerophospholipids
Ntau pawg cawv cawv uas muaj nyob hauv glycerophospholipds pab rau kev faib cov glycerophospholipds raws li. Yog tias tsis muaj cov pab pawg hauv lub taub hau, glycerophospholipds raug xa mus rau phosphatidic acid, thiab yog tias lub taub hau glycerol tam sim no yog hu ua phosphatidylglycerol thiab yog tias muaj choline taub hau pab pawg, nws raug xa mus rau phophatidylcholine.
Sphingolipids yog dab tsi?
Ib hom lipids uas koom nrog cov cell membranes hu ua sphingolipids. Lawv ua raws li kaum yim carbon amine cawv. Hauv cov ntsiab lus yooj yim, sphingolipids muaj cov organic aliphatic amino cawv sphingosine lossis ib yam khoom uas zoo li sphingosine. Txhua tus tswvcuab uas koom nrog pawg sphingolipids muaj cov suab thaj nyuaj lossis yooj yim uas txuas nrog thawj cov pa roj carbon ntawm pawg cawv (C1). Cov tswv cuab uas deviates los ntawm cov qauv no yog sphingomyelin. Cov molecule no muaj ib pab pawg phosphorylcholine uas yog tib lub taub hau lub taub hau muaj nyob hauv phosphatidylcholine.
Vim tias sphingomyelin tsis muaj cov piam thaj moiety, nws raug suav tias yog ib qho analog rau phosphatidylcholine. Ntxiv nrog rau cov suab thaj, tag nrho cov sphingolipids muaj cov roj fatty acid, uas txuas nrog rau cov amino pawg ntawm sphingosine molecule. Lub sphingomyelin yog tib qho sphingolipid uas suav tias yog phospholipid uas ua haujlwm ua ib feem tseem ceeb ntawm cov kab mob lom.
Daim duab 02: Tus qauv ntawm Sphingolipds
Lub sphingomyelin yog tib phosphorous uas muaj sphingolipids uas muaj nyob rau hauv ntau cov ntaub ntawv nyob rau hauv lub paj hlwb. Sphingomyelins kuj muaj nyob rau hauv cov ntshav. Sphingolipidosis thiab sphingolipodystrophy yog ob yam kab mob uas tsim los ntawm kev txawv txav sphingolipid metabolism. Vim muaj qhov sib txuam ntawm sphingolipids hauv lub hlwb, tuaj yeem muaj kev txhim kho ntawm tus kab mob tsawg hu ua Tay Sachs disease condition.
Dab tsi yog qhov zoo sib xws ntawm Glycerophospholipids thiab Sphingolipids?
- Ob leeg Glycerophospholipids thiab Sphingolipids yog cov khoom ntawm cov cell membranes.
- Ob leeg muaj fatty acids.
- Ob leeg tau faib asymmetrically hauv lipid bilayer.
- Ob leeg Glycerophospholipids thiab Sphingolipids yog amphipathic.
Qhov txawv ntawm Glycerophospholipids thiab Sphingolipids yog dab tsi?
Glycerophospholopids vs Sphingolipids |
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| Glycerophospholipds tuaj yeem txhais tau tias yog cov khoom tseem ceeb ntawm daim nyias nyias los yog cov lipid bilayer ntawm cov hlwb. | Sphingolipids txhais tau tias yog chav kawm ntawm lipids uas koom nrog cov cell membranes. |
| qauv | |
| Hauv glycerophospholipids, thaj chaw hydrophobic yog tsim los ntawm ob fatty acids koom nrog glycerol. | Nyob rau hauv sphingolipids, ib leeg fatty acid koom nrog fatty amine, sphingosine thiab sterols. |
| Phosphate pawg | |
| Glycerophospholipids muaj phosphate pawg. | Sphingolipids tuaj yeem lossis tsis muaj phosphate pawg. |
Summary – Glycerophospholipids vs Sphingolipids
Cell membranes yog cov qauv tseem ceeb uas cais cov cell sab hauv los ntawm ib puag ncig sab nraud. Lawv yog tsim los ntawm cov khoom sib txawv xws li Glycerophospholipids thiab Sphingolipids. Glycerophospholipds yog suav tias yog cov ntsiab lus tseem ceeb ntawm lipid bilayer. Feem ntau glycerophospholipds muaj lub taub hau cawv uas yog esterified rau phosphate. Sphingolipids yog lwm chav kawm ntawm lipids uas koom nrog cov membranes. Txhua tus tswvcuab uas koom nrog pawg sphingolipids muaj cov suab thaj nyuaj lossis yooj yim uas txuas nrog cawv ntawm thawj cov pa roj carbon tsuas yog sphingomyelin. Ob leeg muaj fatty acids nyob rau hauv lawv cov qauv. Qhov no yog qhov txawv ntawm Glycerophospholipids thiab Sphingolipids.
