Qhov Tseem Ceeb Qhov txawv - Antigen vs Immunogen
Immunology yog ib ceg ntawm cov tshuaj thiab biology thiab muaj kev txhawj xeeb txog txhua yam ntawm lub cev tiv thaiv kab mob hauv cov kab mob. Qhov no yog ib qho kev kawm ntau vim nws yog ib qho tseem ceeb los txheeb xyuas thiab ntsuam xyuas tus yam ntxwv ntawm lub cev tiv thaiv nws tus kheej tawm tsam kev tawm tsam txawv teb chaws. Ib qho kev tiv thaiv kab mob tiv thaiv kab mob yog pib thaum nkag ntawm ib qho chaw txawv teb chaws uas ua rau muaj kev cuam tshuam los ntawm cov dej ntws mus rau degrade lossis tshem tawm cov chaw txawv teb chaws. Ib qho antigen yog ib lub cev txawv teb chaws los yog ib qho molecule, uas muaj peev xwm khi rau cov tshuaj tiv thaiv kab mob uas tsim los ntawm tus tswv tsev hauv kev teb rau kev lees paub ntawm antigen. Ib qho tshuaj tiv thaiv kab mob kuj yog ib qho txawv teb chaws molecule uas tuaj yeem ua rau lub cev tiv thaiv kab mob los ntawm kev ua rau lub cev tiv thaiv kab mob. Qhov sib txawv tseem ceeb ntawm cov tshuaj tiv thaiv kab mob thiab cov tshuaj tiv thaiv kab mob yog lawv lub peev xwm thiab tsis muaj peev xwm tsim cov tshuaj tiv thaiv kab mob; Ib qho tshuaj tiv thaiv kab mob yuav tsum yog cov tshuaj tiv thaiv kab mob, tab sis cov tshuaj tiv thaiv kab mob yuav tsis tas yuav yog tshuaj tiv thaiv kab mob.
Antigen yog dab tsi?
Antigens yog qhov chaw me me me me uas muaj nyob hauv cellular nto ntawm ntau cov kab mob, fungi, kab mob, plua plav thiab lwm yam cellular thiab noncellular hais. Cov molecules me me no hu ua antigens, thiab lawv tuaj yeem lees paub los ntawm lub cev tiv thaiv kab mob. Antigens yog tsim los ntawm cov proteins, amino acids, lipids, glycolipids, glycoproteins los yog nucleic acid markers. Cov molecules no muaj peev xwm los khi rau cov tshuaj tiv thaiv kab mob (immunoglobulins uas tsim los ntawm B hlwb) tsim los ntawm tus tswv tsev raws li kev tiv thaiv kab mob. Antigens kuj muaj peev xwm ua rau lub cev tiv thaiv kab mob los pib lub cev tiv thaiv kab mob. Yog li antigens tuaj yeem yog ob qho tib si antigenic thiab immunogenic.
Thaum muaj cov tshuaj tiv thaiv kab mob, lawv khi rau cov tshuaj tiv thaiv ntawm qhov chaw txawv teb chaws. Ua raws li cov txheej txheem kev khi tshwj xeeb, lawv tsim cov complexes, thiab cov khoom txawv teb chaws raug rhuav tshem los ntawm cov txheej txheem sib txawv. Cov txheej txheem no suav nrog agglutination, nag lossis daus los yog tua ncaj qha. Kev khi ntawm cov tshuaj tiv thaiv rau cov tshuaj tiv thaiv kuj tuaj yeem ua rau tsim cov T lymphocytes uas ua rau kev ua kom phagocytic mechanisms.
Daim duab 01: Ib qho tshuaj tiv thaiv
Antigens kuj tuaj yeem ua haujlwm tsuas yog khi cov molecules thiab tsis ua rau ua rau lub cev tiv thaiv kab mob. Cov hom antigens no yuav xav tau cov cab kuj molecule los txhawb kev tiv thaiv kab mob. Cov antigens nkag tau yooj yim ua rau tsim cov tshuaj tiv thaiv kab mob thiab khi rau cov tshuaj tiv thaiv tab sis tsis elicit ib qho kev tiv thaiv kab mob. Antigens tam sim no tau siv hauv kev lag luam xws li Enzyme-Linked Immuno Sorbent Assay (ELISA). Cov kev kuaj hauv vitro no tau siv dav hauv kev kuaj mob molecular.
Immunogen yog dab tsi?
Immunogen hais txog ib hom antigen tshwj xeeb. Immunogen muaj lub peev xwm los tawm tsam kev tiv thaiv kab mob thaum khi rau cov tshuaj tiv thaiv kab mob. Feem ntau, cov tshuaj antigens uas qis dua 20 kDa (~ 200 amino acids) yuav tsis yog immunogenic. Yog li ntawd, lawv tau txuas mus rau cov cab kuj protein kom ua rau nws immunogenic. Cov neeg nqa khoom muaj protein ntau yog albumin, ovalbumin thiab Keyhole Limpet Hemocyanin (KLH). Ntxiv rau qhov loj me, lwm yam uas cuam tshuam rau immunogenicity yog qhov concentration ntawm antigen uas tau txhaj. Qhov qis dua qhov immunogenicity ntawm cov antigen, qhov ntau concentrated lub inoculation ntim yuav tsum yog. Tag nrho cov immunogens yog antigenic.
Dab tsi yog qhov zoo sib xws ntawm Antigen thiab Immunogen?
- Ob leeg muaj nyob rau ntawm lub xov tooj ntawm tes ntawm cov kab mob kab mob lossis cov chaw txawv teb chaws.
- Ob qho tib si yog tsim los ntawm cov proteins, lipids, glycoproteins lossis glycolipids.
- Ob leeg ua tus cim rau tus tswv tsev los tsim cov tshuaj tiv thaiv.
- Ob leeg muaj peev xwm khi rau cov tshuaj tiv thaiv kab mob sib txawv ntawm cov tshuaj sib txawv.
- Ob leeg yog cov tshuaj tiv thaiv kab mob.
- Ob leeg tuaj yeem siv tau nyob rau hauv vitro mob hauv kev kuaj mob molecular.
Qhov txawv ntawm Antigen thiab Immunogen yog dab tsi?
Antigen vs Immunogen |
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| Ib qho tshuaj tiv thaiv yog lub cev txawv teb chaws lossis cov molecule, uas muaj peev xwm khi rau cov tshuaj tiv thaiv kab mob tab sis tsis tas yuav pib tiv thaiv kab mob. | Immunogen yog ib qho txawv teb chaws molecule lossis ib hom antigen uas tuaj yeem ua rau lub cev tiv thaiv kab mob los ntawm kev ua rau lub cev tiv thaiv kab mob. |
| Immunogenic Property | |
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Immunogenic cov cuab yeej tsis pom nyob rau hauv tag nrho cov antigens; tsuas yog qee qhov yog immunogenic. Tsis muaj tshuaj tiv thaiv kab mob antigens tuaj yeem tsim cov tshuaj tiv thaiv kab mob los ntawm kev sib txuas nrog cov cab kuj. |
Txhua yam immunogens yog immunogenic. |
Summary – Antigen vs Immunogen
Antigens thiab immunogens muaj ntau dua lossis tsawg dua qhov zoo sib xws thiab txawv ntawm lawv lub peev xwm los txhawb kev tiv thaiv kab mob. Tag nrho cov antigens thiab immunogens yog antigenic thiab muaj peev xwm los khi rau cov tshuaj tiv thaiv. Tag nrho cov antigens tsis yog immunogenic li tag nrho cov antigens tsis muaj peev xwm elicit lub cev tiv thaiv kab mob, whereas tag nrho cov immunogens yog immunogenic. Tsis yog-immunogenic antigens tuaj yeem tsim cov tshuaj tiv thaiv kab mob los ntawm kev ua rau lawv mus rau hauv cov cab kuj molecule. Qhov no yog qhov txawv ntawm antigen thiab immunogen. Vim cov khoom sib txawv no, ob qho tib si molecules ua lub luag haujlwm tseem ceeb hauv kev kuaj mob molecular nyob rau hauv vitro mob.
Download PDF Version of Antigen vs Immunogen
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li daim ntawv ceeb toom. Thov download PDF version ntawm no Qhov txawv Ntawm Antigen thiab Immunogen
