Qhov Tseem Ceeb Qhov txawv - Ubiquinone vs Ubiquinol
Electron thauj saw siv qhov chaw nyob rau hauv mitochondrion inner membrane thiab electrons raug pauv los ntawm ib qho protein ntau mus rau lwm qhov hauv qhov kev txiav txim ntawm lawv qhov peev xwm txo qis. Electron pas dej yog tam sim no nyob rau hauv thiaj li yuav ntes cov electrons tso tawm los ntawm complex I, II thiab III nyob rau hauv lub electron thauj saw uas thaum kawg koom nyob rau hauv tsim dej txuam nrog complex IV. Txoj kev zoo ntawm kev thauj khoom hluav taws xob no ua rau cov tshuaj electrochemical gradient; proton motive force uas tsav cov txheej txheem ntawm ATP synthesis ntawm ATP synthase. Cov txheej txheem tag nrho yog hu ua Oxidative phosphorylation. Coenzyme Q10 ua raws li lub pas dej hluav taws xob rau cov hluav taws xob tso tawm los ntawm Complex I thiab II thiab xa cov electrons mus rau Complex III hauv cov txheej txheem hu ua Q cycle. Qhov sib txawv tseem ceeb ntawm ubiquinone thiab ubiquinol yog tias ubiquinone yog daim ntawv oxidized ntawm Coenzyme Q10 thaum ubiquinol yog qhov txo qis ntawm Co enzyme Q10.
Ubiquinone yog dab tsi?
Ubiquinone (2, 3-dimethoxy-5-methyl-6-multiprenyl-1, 4-benzoquinone) kuj raug hu ua CoQ10, thiab nws yog ib qho hydrophobic compound uas pom nyob rau hauv lipid-nplua nuj thaj chaw ntawm daim nyias nyias; Nws nkag mus raws li lipid ob txheej txheej. Ubiquinone yog daim ntawv oxidized tag nrho uas tau nkag mus rau qhov txo qhov sib npaug uas tau los ntawm oxidation ntawm NADH thiab FADH2 los ntawm complex I thiab II. Yog li, ubiquinone tau txais cov electrons tso tawm thaum lub sij hawm oxidation txheej txheem thiab undergoes txo mus rau hauv nws txo daim ntawv ubiquinol, yog li ua raws li ib tug electron pas dej ua ke.
Daim duab 01: Kev hloov pauv Ubiquinone rau hauv Ubiquinol
Kev sib txuas ntawm ubiquinone / CoQ10 tshwm sim los ntawm txoj hauv kev mevalonate ntawm cov roj cholesterol synthesis nyob rau hauv feem ntau cov ntaub so ntswg, thiab tus Tsov tus tw ntawm isoprene units ua raws li lub electron cab kuj nyob rau hauv hydrophobic tej yam kev mob.
YUbiquinol yog dab tsi?
Ubiquinol (5, 6-dimethoxy-3-methylcyclohexa-2, 5-diene-1, 4-diol) yog hydrophobic molecule uas muaj cov isoprene tail zoo ib yam li cov qauv ntawm ubiquinone thiab yog synthesized nyob rau hauv lub siab. Ubiquinol (QH2) yog daim ntawv txo qis ntawm CoQ10, thiab nws muaj peev xwm pub cov khoom siv hluav taws xob ntes mus rau complex III ntawm cov khoom siv hluav taws xob thauj khoom thiab hloov rov qab mus rau nws daim ntawv oxidized. Cov txheej txheem no yuav siv sij hawm qhov chaw ntawm hlau - sulfur chaw ntawm lub complex III. Ubiquinol nyob rau hauv nws daim ntawv txo yog ib qho electron nplua nuj molecule. Nws yog hydrophobic, thiab nws cov haujlwm tsuas yog txwv rau cov txheej txheem membrane raws li nws tuaj yeem nkag mus raws li lipid ob txheej txheej.
Daim duab 02: Ubiquinol tshuaj ntxiv
Ntxiv rau nws txoj haujlwm hauv cov saw hlau thauj hluav taws xob, ubiquinol yog lub zog lipid soluble antioxidant uas muaj peev xwm tiv thaiv lub cev los ntawm oxidative kev nyuaj siab los ntawm cov dawb radicals. Yog li, ubiquinol kuj tseem tau noj los ntawm cov neeg laus, thiab kev ntsuas ubiquinol raug coj los ntsuas kev laus ntawm cov hlwb.
Dab tsi yog qhov zoo sib xws ntawm Ubiquinone thiab Ubiquinol?
- Ubiquinone thiab ubiquinol yog hydrophobic.
- Ob leeg yog lipid soluble.
- Ob leeg muaj ib txoj saw isoprene, uas yog cov khoom siv hluav taws xob.
- Ob lub molecules koom nrog Q lub voj voog thiab ua raws li lub pas dej hluav taws xob hauv cov saw hlau thauj khoom.
- Ob leeg yog ob hom tib yam sib xyaw (CoQ10).
Qhov txawv ntawm Ubiquinone thiab Ubiquinol yog dab tsi?
Ubiquinone vs Ubiquinol |
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| Ubiquinone yog daim ntawv oxidized tag nrho ntawm CoQ10 thiab nkag tau cov electrons kom ncav cuag lub xeev txo. | Ubiquinol yog daim ntawv txo qis ntawm CoQ10 thiab tso tawm cov hluav taws xob nkag mus rau lub xeev oxidized. |
| kev ruaj ntseg | |
| Ubiquinone tsis ruaj khov. | Ubiquinol ruaj khov dua. |
| xim | |
| Ubiquinone muaj lub ntsej muag daj. | Ubiquinol yog mis nyuj dawb hauv tsos. |
| Ubiquinone lees txais cov hluav taws xob tso tawm los ntawm txoj haujlwm I thiab II ntawm cov saw hlau thauj hluav taws xob thiab ua raws li lub pas dej hluav taws xob. | Ubiquinol tso cov electrons mus rau complex III ntawm Q lub voj voog thiab kuj ua raws li lub zog lipid antioxidant. |
Summary – Ubiquinone vs Ubiquinol
CoQ10 yog ib qho kev kawm dav dav vim nws cov haujlwm hauv cov khoom siv hluav taws xob thauj khoom raws li tus neeg sawv cev redox thiab muaj ob lub ntsiab lus: daim ntawv oxidized, ubiquinone thiab daim ntawv txo, ubiquinol. Ubiquinone thiab ubiquinol koom nrog hauv kev kaw cov hluav taws xob hauv cov saw hlau thauj hluav taws xob los ntawm txoj haujlwm I thiab II mus rau complex III. Tsis tas li ntawd, ob qhov sib xyaw no yog siv los kho thaum lub cev tsis ua haujlwm, thiab kev laus thiab, yog li kev tshawb fawb tam sim no ntawm biochemists. Qhov sib txawv tseem ceeb ntawm ubiquinone thiab ubiquinol yog tias ubiquinone yog daim ntawv oxidized ntawm CoQ10 thaum ubiquinol yog daim ntawv txo ntawm CoQ10.
Download PDF Version of Ubiquinone vs Ubiquinol
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li daim ntawv ceeb toom. Thov download PDF version ntawm no Qhov txawv Ntawm Ubiquinone thiab Ubiquinol.
