Qhov Tseem Ceeb - Dyslipidemia vs Hyperlipidemia
Dyslipidemia thiab hyperlipidemia yog ob yam mob uas cuam tshuam rau qib lipid hauv lub cev. Ib qho kev sib txawv ntawm qib lipid hauv lub cev los ntawm qhov qub thiab qhov tsim nyog hauv kev kho mob tau pom tias yog dyslipidemia. Hyperlipidemia yog ib hom dyslipidemia uas cov qib lipid nce siab. Qhov sib txawv tseem ceeb ntawm dyslipidemia thiab hyperlipidemia yog tias dyslipidemia yog hais txog qhov txawv txav ntawm qib lipid whereas hyperlipidemia yog hais txog qhov nce siab hauv lipid.
Dyslipidemia yog dab tsi?
Txhua yam txawv txav hauv cov qib lipid hauv lub cev raug txheeb xyuas tias yog dyslipidemia.
Ntau hom dyslipidemia suav nrog
Hypopidemia
Lipid qib ntawm lub cev tau txo qis hauv qhov xwm txheej no. Cov protein ntau zog tsis txaus noj haus, malabsorption hnyav, thiab plab hnyuv lymphangiectasia yog qhov ua rau.
Hypolipoproteinemia
Tus kab mob no yog tshwm sim los ntawm caj ces los yog kis tau. Daim ntawv ntawm tsev neeg ntawm hypolipoproteinemia yog asymptomatic thiab tsis xav tau kev kho mob. Tab sis muaj qee yam ntawm cov mob no uas hnyav heev.
Kev mob caj ces cuam tshuam nrog tus mob no yog,
- Abeta lipoproteinemia
- Tsev neeg hypobetalipoproteinemia
- Chylomicron retention disease
- Lipodystrophy
- Lipomatosis
- YDyslipidemia thaum cev xeeb tub
YHyperlipidemia yog dab tsi?
Hyperlipidemia yog ib hom dyslipidemia uas yog tus cwj pwm los ntawm kev nce qib lipid txawv txav.
YPrimary Hyperlipidemia
Thawj hyperlipidemias yog vim muaj qhov tsis xws luag hauv cov lipid metabolism.
Kev faib tawm
Kev mob ntawm VLDL thiab chylomicrons- hypertriglyceridemia ib leeg
Qhov feem ntau ua rau cov kab mob no yog cov kab mob tsis xws luag hauv ntau cov noob. Muaj qhov nce me ntsis hauv qib VLDL.
Kev mob ntawm LDL- hypercholesterolemia ib leeg
Muaj ntau pab pawg ntawm pawg no
Heterozygous Tsev Neeg Hypercholesterolemia
Qhov no yog ib qho teeb meem autosomal dominant monogenic teeb meem. Feem ntau ntawm cov xwm txheej, cov tsos mob thiab cov tsos mob tsis tuaj thiab yog li ntawd, feem ntau ntawm cov neeg mob tseem tsis tau kuaj pom. Tsev neeg hypercholesterolemia yuav tsum xav tias yog tus neeg mob muaj cov roj cholesterol ntau hauv cov ntshav uas tsis teb rau kev hloov pauv kev noj haus. Associated kho mob nta yog xanthomatous thickening ntawm lub Achilles leeg thiab xanthomas tshaj lub extensor tendons ntawm cov ntiv tes.
Homozygous Tsev Neeg Hypercholesterolemia
Nov yog ib yam mob uas tsis tshua muaj tshwm sim ntawm cov menyuam yaus. Qhov xwm txheej no tshwm sim los ntawm qhov tsis muaj LDL receptors hauv lub siab. Cov neeg mob yuav muaj cov roj cholesterol LDL ntau hauv cov ntshav.
Kev hloov pauv hauv Apo protein B-100 Gene
Cov neeg mob uas muaj qhov teeb meem no kuj tseem muaj LDL ntau hauv cov ntshav.
YPolygenic Hypercholesterolemia
Kev tsis zoo ntawm HDL
Qhov no yog ib qho teeb meem autosomal recessive yam ntxwv los ntawm qhov qis HDL concentration.
Cov yam ntxwv ntawm tus kab mob no yog
- Cov roj cholesterol ntau hauv cov hlab ntsha thiab cov hlwb reticuloendothelial ua rau cov txiv kab ntxwv xim tonsils thiab hepatosplenomegaly.
- Muaj feem ntau ntawm kev tsim cov kab mob plawv, corneal opacities, thiab polyneuropathy.
Combined hyperlipidemia (ua ke hypercholesterolemia thiab hypertriglyceridemia)
Muaj ob hom kab mob no ua tsev neeg ua ke hyperlipidemia thiab cov ntshavlipidemia seem.
YSecondary Hyperlipidemias
Thaum cov qib lipid nce siab vim yog qee yam kab mob hauv qab nws hu ua theem nrab hyperlipidemia.
Caus
- YHypothyroidism
- Kev rog
- Lub raum tsis ua haujlwm
- Nephrotic Syndrome
- YDysglobulinemia
- Hepatic dysfunction
- Cov tshuaj xws li OCP
Nyob zoo ib tsoom niam txiv kwv tij neej tsas sawv daws.
Kev tswj hwm
Vim tias feem ntau ntawm cov neeg mob hyperlipidemia tseem nyob asymptomatic kom txog rau thaum kev txhim kho ntawm cov kab mob hauv lub cev, kev tshuaj xyuas cov tib neeg uas muaj qhov pheej hmoo yog qhov tseem ceeb heev.
Risk Factors
- Tsev neeg keeb kwm ntawm cov kab mob coronary artery
- Tsev neeg keeb kwm ntawm cov kab mob lipid
- Lub xub ntiag ntawm xanthoma
- Kev muaj xanthelasma lossis pob txha pob txha ua ntej hnub nyoog 40
- Kev rog
- Hypertension
- mob pancreatitis
Kev tswj cov neeg mob tuaj yeem muab faib ua ob pawg raws li kev tswj hwm tshuaj thiab kev tswj tsis yog tshuaj.
Nonpharmacological Management
Kev hloov pauv noj zaub mov yuav tsum ua raws li tus kws kho mob qhia.
- Kev noj cov roj saturated thiab trans unsaturated yuav tsum raug txo kom tsawg dua 7- 10% ntawm tag nrho lub zog.
- Cov roj cholesterol txhua hnub yuav tsum raug txo kom tsawg dua 250mg
- Kev noj zaub mov muaj zog xws li dej qab zib yuav tsum tau txo
- Kev haus cawv yuav tsum txo qis
- Kev noj cov Omega peb fatty acids uas muaj zaub mov yuav tsum tau nce ntxiv.
Tshuaj Tswj Tshuaj
- Predominant hypercholesterolemia tuaj yeem kho nrog statins.
- Kev sib xyaw ua ke feem ntau yog siv rau hauv kev kho mob sib xyaw hyperlipidemia. Statins thiab fibrates yog cov tshuaj suav nrog hauv cov tshuaj noj.
- Fibrates yog siv los ua thawj kab kev kho mob hauv kev tswj hwm tus mob hypercholesterolemia.
Qhov txawv ntawm Dyslipidemia thiab Hyperlipidemia yog dab tsi?
YDyslipidemia vs Hyperlipidemia |
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Txhua yam txawv txav hauv cov qib lipid hauv lub cev raug txheeb xyuas tias yog dyslipidemia. | Hyperlipidemia yog ib hom dyslipidemia uas cov qib lipid nce siab. |
Hauv dyslipidemia, qib lipid tuaj yeem nce lossis txo qis. | Hauv hyperlipidemia, ib txwm muaj qhov nce hauv lipid concentration. |
Summary – Dyslipidemia vs Hyperlipidemia
Dyslipidemia yog hais txog ib qho kev txawv txav hauv cov qib lipid thaum hyperlipidemia yog hais txog qhov nce siab hauv qib lipid. Qhov no yog qhov sib txawv tseem ceeb ntawm dyslipidemia thiab hyperlipidemia. Kev siv sijhawm ntev ntawm cov tshuaj lipid txo qis xws li statins tuaj yeem muaj kev cuam tshuam tsis zoo nrog rau lub siab thiab lub raum puas. Yog li ntawd, yuav tsum tau saib xyuas ntau dua rau kev tswj hwm cov tshuaj tsis yog tshuaj ntawm cov tshuaj lipid los ntawm kev hloov kho lub neej.
Download PDF Version of Dyslipidemia vs Hyperlipidemia
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li cov ntawv sau tseg. Thov download PDF version ntawm no Qhov txawv Ntawm Dyslipidemia thiab Hyperlipidemia.