Qhov Tseem Ceeb - Fatty Acid Synthesis vs Beta Oxidation
A fatty acid yog carboxylic acid uas tsim los ntawm ib tug ntev hydrocarbon saw thiab ib tug davhlau ya nyob twg carboxyl pawg. Fatty acids yog cov khoom tseem ceeb ntawm cov rog thiab roj. Hydrocarbon saw ntawm fatty acid yuav saturated (tsis muaj ob daim ntawv cog lus ntawm carbon atoms) los yog unsaturated (muaj ob daim ntawv cog lus ntawm carbon atoms). Lawv tuaj yeem ua tau ceg lossis tsis muaj ceg. Fatty acids yog ib hom kev noj zaub mov tseem ceeb ntawm cov tsiaj. Thaum cov fatty acids tawg, cov tshuaj tiv thaiv catabolic tso tawm ntau lub zog hauv daim ntawv ntawm ATP. Yog li ntawd, ntau lub hlwb siv fatty acids los ua lub zog los tsim lub zog los ntawm catabolism. Fatty acid synthesis thiab fatty acid oxidation (beta oxidation) tseem ceeb sib npaug. Fatty acid synthesis yog tsim cov fatty acid molecules los ntawm kev sib txuas ntawm acetyl coenzyme A molecules ua ke los ntawm fatty acid synthases enzymes. Beta oxidation yog cov txheej txheem ntawm kev rhuav tshem cov roj fatty acids rau hauv acetyl-CoA los ntawm ntau cov enzymes. Qhov sib txawv tseem ceeb ntawm fatty acid synthesis thiab beta oxidation yog tias fatty acid synthesis yog cov txheej txheem anabolic thaum beta oxidation yog txheej txheem catabolic.
Fatty Acid Synthesis yog dab tsi?
Fatty acid synthesis yog tsim cov fatty acids los ntawm acetyl-CoA thiab NADPH. Qhov no yog cov txheej txheem anabolic uas yog catalyzed los ntawm ib qho enzyme hu ua fatty acid synthase. Fatty acid synthase yog multienzyme complex. Lawv pom nyob rau hauv cytoplasm ntawm cov hlwb hauv ob qho tib si prokaryotes thiab eukaryotes. Lub precursor molecule acetyl coenzyme A yog muab los ntawm txoj kev glycolytic. Nws yog tsim nyob rau hauv mitochondrion los ntawm pyruvate dehydrogenase enzyme. Fatty acid biosynthesis xav tau NADPH ua tus reductant.
Daim duab 01: Fatty Acid Biosynthesis
NADPH yog tsim los ntawm oxaloacetate hauv ob-kauj ruam cov tshuaj tiv thaiv. Lub condensation ntawm ob chav nyob carbon ntawm acetyl coenzyme A ua rau ntev hydrocarbon chains uas thaum kawg tsim cov fatty acid molecule. Qhov ntev ntawm cov saw hlau hydrocarbon tuaj yeem sib txawv ntawm ntau hom fatty acids.
Beta Oxidation yog dab tsi?
Beta oxidation lossis fatty acid oxidation yog cov txheej txheem ntawm kev rhuav tshem fatty acid molecules rau hauv acetyl-CoA molecules los ntawm catabolic cov tshuaj tiv thaiv. Fatty acids ua haujlwm zoo rau lub zog. Yog li ntawd, ib tug loj npaum li cas ntawm lub zog molecules raug tso tawm nyob rau hauv daim ntawv ntawm ATP thaum lub sij hawm beta oxidation. Fatty acid tawg tshwm sim hauv cytoplasm ntawm prokaryotes thiab hauv mitochondria ntawm eukaryotes. Qhov catabolism no yog catalyzed los ntawm ntau cov enzymes cais nrog rau mitochondrial trifunctional proteins. Beta oxidation siv NAD ua tus txais hluav taws xob thaum lub sij hawm catabolism. Cov khoom tsim acetyl-CoA nkag mus rau lwm txoj hauv kev metabolic.
Daim duab 02: Beta Oxidation
Ntau cov ntaub so ntswg oxidize fatty acids los tsim lub zog. Txawm li cas los xij, qee cov ntaub so ntswg tsis siv fatty acids rau lawv cov kev xav tau ntawm lub zog. Lawv siv cov piam thaj los ua lawv lub zog.
Qhov txawv ntawm Fatty Acid Synthesis thiab Beta Oxidation yog dab tsi?
Fatty Acid Synthesis vs Beta Oxidation |
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| Fatty Acid Synthesis yog tsim cov fatty acid molecules los ntawm acetyl coenzyme A thiab NADPH molecules los ntawm cov tshuaj tiv thaiv anabolic los ntawm enzymes. | Beta oxidation yog oxidation lossis tawg ntawm fatty acids rau hauv acetyl coenzyme A thiab NADH los ntawm cov tshuaj catabolic los ntawm enzymes. |
| Fatty Acid Synthesis tshwm sim hauv cytoplasm ntawm ob qho tib si prokaryotes thiab eukaryotes. | Beta Oxidation tshwm sim hauv cytoplasm ntawm prokaryotes thiab hauv mitochondria ntawm eukaryotes. |
| Enzymes koom nrog | |
| Fatty acid synthesis yog catalyzed los ntawm fatty acid synthases. | Beta oxidation yog catalyzed los ntawm ntau cov enzymes cais, suav nrog mitochondrial trifunctional proteins. |
| ATP Production | |
| Fatty acid synthesis tsis tsim ATP. | Beta oxidation ua rau muaj zog molecule ATP. |
| Reductant siv | |
| Fatty acid synthesis siv NADPH ua tus reductant. | Beta oxidation siv NADH thiab FADH ua cov reductants. |
| Kev pib ntawm txheej txheem | |
| Fatty acid synthesis pib nrog ACP (acyl pawg neeg nqa khoom). | Beta oxidation pib nrog coenzyme A. |
Summary – Fatty Acid Synthesis vs Beta Oxidation
Fatty acids yog lub zog zoo. Yog li ntawd, lawv yog synthesized thiab oxidized nyob rau hauv cov kab mob. Fatty acid synthesis yog tsim cov fatty acids los ntawm precursor molecule acetyl coenzyme A. Nws yog cov txheej txheem anabolic uas tshwm sim hauv cytoplasm ntawm cov hlwb. Nws yog catalyzed los ntawm ib tug multienzyme complex hu ua fatty acid synthase. Beta oxidation los yog fatty acid tawg yog qhov opposite ntawm fatty acid synthesis. Thaum lub sij hawm beta oxidation, fatty acids tau tawg mus rau acetyl coenzyme A. Nws yog cov txheej txheem catabolic thiab tso tawm ntau lub zog. Qhov no yog qhov txawv ntawm fatty acid synthesis thiab beta oxidation.
Download PDF Version of Fatty Acid Synthesis vs Beta Oxidation
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li cov ntawv sau tseg. Thov download PDF version ntawm no Qhov txawv Ntawm Fatty Acid Synthesis thiab Beta Oxidation.
