Qhov Tseem Ceeb Qhov txawv - Lipase vs Amylase
Cov enzyme tuaj yeem yog cov tshuaj catalytic protein uas ua rau muaj txiaj ntsig zoo thiab ua haujlwm ntawm cov tshuaj tiv thaiv tshuaj tsis muaj zog koom nrog cov tshuaj tiv thaiv nws tus kheej. Lipase thiab Amylase yog ob lub plab zom mov loj. Lub lipase yog ib qho enzyme uas belongs rau subclass ntawm esterases uas catalyzes hydrolysis ntawm cov rog. Amylase yog ib qho enzyme uas catalyzes hydrolysis ntawm starch rau hauv qab zib. Qhov no yog qhov sib txawv tseem ceeb ntawm amylase thiab lipase. Lub hom phiaj ntawm tsab xov xwm no yog qhia txog qhov sib txawv ntawm lipase thiab amylase enzymes.
Lipase yog dab tsi?
A lipase yog ib qho enzyme uas catalyzes hydrolysis ntawm lipids. Nws belongs rau subclass ntawm esterases. Lipases ua tiav lub luag haujlwm tseem ceeb hauv kev zom zaub mov, thauj thiab ua cov khoom noj lipids xws li triglycerides, rog, roj hauv tib neeg lub plab zom mov. Raws li ib qho piv txwv, pancreatic lipase tuaj yeem zom cov zaub mov triglyceride hauv lub plab zom mov thiab hloov triglyceride substrates rau hauv monoglycerides thiab ob fatty acids. Tib neeg kuj muaj ntau yam lipase enzymes, suav nrog lub siab lipase, endothelial lipase, thiab lipoprotein lipase.
Y Amylase yog dab tsi?
Ib amylase yog ib qho tseem ceeb ntawm lub plab zom mov enzyme uas catalyzes hydrolysis ntawm starch rau hauv cov suab thaj yooj yim. Lawv yog glycoside hydrolases thiab ua rau α-1, 4-glycosidic bonds. Amylase muaj nyob rau hauv tib neeg cov qaub ncaug, qhov twg nws pib cov txheej txheem tshuaj lom neeg ntawm digestion. Thaum cov zaub mov nkag mus rau hauv lub qhov ncauj, cov khoom noj uas muaj cov hmoov txhuv nplej siab ntau tab sis cov ntsiab lus suab thaj me ntsis xws li mov thiab qos yaj ywm, yuav tau txais ib qho qab zib me ntsis raws li cov khoom noj chewed. Qhov no yog vim amylase hloov qee cov hmoov txhuv nplej siab rau hauv qab zib. Tib neeg pancreas thiab salivary caj pas kuj zais alpha-amylase rau hydrolyze cov hmoov txhuv nplej siab rau hauv disaccharides thiab tri-lossis oligosaccharides uas hloov los ntawm lwm cov enzymes rau cov piam thaj los muab lub cev nrog lub zog. Cov nroj tsuag thiab qee cov kab mob kuj tsim amylase. Amylase yog thawj enzyme uas tau tshawb pom thiab cais tawm los ntawm Anselme Payen hauv xyoo 1833. Muaj cov protein ntau amylase sau los ntawm cov ntawv Greek sib txawv.
Dab tsi yog qhov txawv ntawm Amylase thiab Lipase?
Definition:
Lipase: Lipase yog ib qho enzyme uas koom nrog hauv hydrolysis ntawm lipids.
Amylase: Amylase yog ib qho enzyme koom nrog hauv hydrolysis ntawm starch molecules rau hauv qab zib.
Hom Enzyme thiab Classification:
Lipase: Ib chav kawm ntawm hydrolases hu ua Esterases
YAmylase: Hydrolases. Nws tau muab faib ua peb pawg hu ua α-amylase, β-amylase, thiab γ-Amylase.
Daim ntawv cog lus:
Lipase: Lipase ua rau ester daim ntawv cog lus hauv lipid.
Amylase: Amylase ua rau glycosidic bonds hauv cov carbohydrates.
Substrate:
Lipase: Fatty acids esters xws li triglycerides, rog, roj
Amylase: Starch molecules
End Product:
Lipase: Glycerol, Di-glycerides, Mono-glycerides, fatty acids nyiam cov rog tsawg dua cov rog
Amylase: Oligosaccharides (Dextrose, m altodextrin) thiab disaccharides (M altose)
Enzyme secretion Organ hauv tib neeg lub cev:
Lipase: Cov kua qaub lipase thiab pancreatic lipase yog tso tawm los ntawm cov qog ua kua qaub pancreas feem. Lwm cov piv txwv yog hepatic lipase, endothelial lipase, thiab lipoprotein lipase.
Amylase: Cov qog qaub ncaug zais cov salivary amylase thiab pancreatic amylase secreted los ntawm pancreas.
Function:
Lipase: Lipid metabolism
Amylase: Carbohydrate metabolism
Mechanism of Action:
Lipase: Cov rog tsis yog dej-soluble tab sis lipase yaj hauv dej. Yog li ntawd, lipase tsis tuaj yeem ncaj qha zom cov roj molecules. Ua ntej, rog, kua tsib ntsev los ntawm lub gallbladder yuav tsum zom cov rog thiab emulsify lawv mus rau hauv dej-soluble hlaws.
Amylase: Ob qho amylase thiab hmoov txhuv nplej siab yog cov dej soluble, yog li amylase enzymes secreted rau hauv lub plab zom mov sib xyaw yooj yim nrog cov khoom noj (chyme) thiab yooj yim zom cov carbohydrates hauv cov zaub mov.
Cov teeb meem kev noj qab haus huv:
Lipase: Lysosomal lipase deficiency tuaj yeem ua rau tus kab mob Wolman nrog rau Cholesteryl Ester Storage Disease (CESD) uas yog cov kab mob autosomal recessive. Ob yam kab mob no tshwm sim los ntawm kev hloov pauv hauv cov noob encoding lub enzyme.
Amylase: Qhov nce qib ntawm amylase hauv cov ntshav ntshav yog qhov qhia tau tias tus neeg tuaj yeem raug mob los ntawm tus mob pancreatic o, peptic ulcer, cyst zes qe menyuam lossis kab mob qog.
Siv:
Lipase: Nws yog siv hauv kev lag luam ci, ntxhua khaub ncaws, Biocatalyst, Kev tsim cov khoom siv hluav taws xob.
Amylase:
Cov hmoov nplej ntxiv: Amylase yog siv hauv cov txheej txheem ua khob cij thiab ua rau cov hmoov txhuv nplej siab hauv cov hmoov nplej rau hauv cov suab thaj yooj yim. Cov poov xab ces pub rau cov suab thaj yooj yim no thiab hloov mus rau hauv cawv thiab CO2 thiab qhov no ua rau tsw qab thiab ua rau lub khob cij nce.
Fermentation: Ob leeg alpha thiab beta amylase yog qhov tseem ceeb hauv brewing npias thiab cawv ua los ntawm cov suab thaj tau los ntawm cov hmoov txhuv nplej siab.
Amylase tshem tawm cov hmoov txhuv nplej siab los ntawm cov khaub ncaws starched thiab, yog li ntawd, nws yog siv los ua tshuaj ntxuav tes.
