YL-tyrosine vs Tyrosine
Qhov sib txawv tseem ceeb ntawm l-tyrosine thiab tyrosine yog lub peev xwm tig lub dav hlau polarized teeb. Tyrosine yog ib qho kev ua haujlwm lom neeg uas tshwm sim tsis tseem ceeb α-amino acid. Nws tuaj yeem tshwm sim hauv ob hom isomers, vim yog tsim ntawm ob qhov sib txawv enantiomers nyob ib ncig ntawm chiral carbon atom. Cov no yog hu ua L- thiab D- cov ntawv los yog sib npaug rau sab laug thiab sab xis teeb tsa, feem. Cov ntawv L- thiab D- cov ntawv no tau hais tias ua haujlwm kho qhov muag, thiab tig lub dav hlau polarized lub teeb nyob rau hauv ib qho kev taw qhia sib txawv xws li clockwise lossis anticlockwise. Yog hais tias lub dav hlau polarized lub teeb tig lub tyrosine anticlockwise, ces lub teeb qhia levorotation, thiab nws yog hu ua l-tyrosine. Txawm li cas los xij, nws yuav tsum tau ua tib zoo sau tseg ntawm no tias D- thiab L- labeling ntawm isomers tsis zoo ib yam li d- thiab l- labeling.
YTyrosine yog dab tsi?
Tyrosine yog ib qho tsis tseem ceeb amino acid, uas yog synthesized nyob rau hauv peb lub cev los ntawm ib tug amino acid hu ua phenylalanine. Nws yog ib qho tseem ceeb ntawm cov organic compound uas muaj amine (-NH2) thiab carboxylic acid (-COOH) cov pab pawg ua haujlwm nrog cov tshuaj formula C 6 H 4(OH)-CH2-CH(NH2)-COOH. Cov ntsiab lus tseem ceeb ntawm tyrosine yog carbon, hydrogen, oxygen, thiab nitrogen. Tyrosine yog suav tias yog ib qho (alpha-) α-amino acid vim hais tias ib pawg carboxylic acid thiab ib pawg amino yog txuas rau tib cov pa roj carbon atom hauv cov pob txha pob txha. Cov qauv molecular ntawm tyrosine yog muab rau hauv daim duab 1.
Daim duab 1: Cov qauv molecular ntawm tyrosine (carbon atom yog chiral lossis asymmetric carbon atom thiab kuj sawv cev rau alpha- carbon atom)
Y Tyrosine plays lub luag haujlwm tseem ceeb hauv photosynthesis ntawm cov nroj tsuag. Nws ua raws li lub tsev thaiv rau kev sib txuas ntawm ntau yam tseem ceeb neurotransmitters tseem hu ua cov tshuaj hlwb xws li epinephrine, norepinephrine, thiab dopamine. Tsis tas li ntawd, tyrosine yog qhov tseem ceeb los tsim cov xim melanin, uas yog lub luag haujlwm rau tib neeg cov tawv nqaij xim. Tsis tas li ntawd, tyrosine kuj tseem pab ua haujlwm ntawm adrenal, thyroid, thiab pituitary qog rau kev tsim khoom thiab tswj lawv cov tshuaj hormones.
YL- tyrosine yog dab tsi?
Tyrosine muaj plaub pawg sib txawv nyob ib puag ncig 2 ndcarbon, thiab nws yog ib qho asymmetric configuration. Tsis tas li ntawd, tyrosine raug suav hais tias yog ib qho kev ua haujlwm zoo ntawm cov amino acid vim muaj cov asymmetric lossis chiral carbon atom. Cov asymmetric carbon atoms nyob rau hauv tyrosine muaj nyob rau hauv daim duab 1. Yog li, tyrosine tuaj yeem tsim cov stereoisomers, uas yog isomeric molecules uas muaj cov qauv molecular zoo sib xws, tab sis sib txawv ntawm peb-dimensional (3-D) cov lus qhia ntawm lawv cov atoms hauv qhov chaw. Hauv biochemistry, enantiomers yog ob lub stereoisomers uas tsis yog-superimposable daim iav duab ntawm ib leeg. Tyrosine muaj nyob rau hauv ob daim ntawv enantiomer hu ua L- thiab D- teeb tsa thiab cov enantiomers ntawm tyrosine tau muab rau hauv daim duab 2.
Daim duab 2: Enantiomers ntawm tyrosine amino acid. L-daim ntawv ntawm tyrosine enantiomers, COOH, NH2, H, thiab R pawg yog teem ib ncig ntawm asymetric C atom nyob rau hauv ib tug clockwise kev taw qhia whereas D-daim ntawv lawv yog teem nyob rau hauv anticlockwise kev taw qhia. Cov L- thiab D- cov ntaub ntawv ntawm tyrosine yog chiral molecules uas tuaj yeem tig lub dav hlau ntawm lub teeb pom kev sib txawv xws li L-forms thiab D-forms tuaj yeem tig lub dav hlau polarized los ntawm sab laug (l- daim ntawv) lossis rau sab xis. (d- daim ntawv).
L- tyrosine thiab D- tyrosine yog enantiomers ntawm ib leeg thiab muaj cov yam ntxwv ntawm lub cev zoo ib yam, sib nrug ntawm cov kev taw qhia uas lawv tig lub teeb polarized. Txawm li cas los xij, qhov nomenclature ntawm D thiab L tsis muaj nyob rau hauv cov amino acids xws li tyrosine. Tsis tas li ntawd, lawv muaj qhov tsis zoo ntawm daim iav duab kev sib raug zoo, thiab cov duab iav no tuaj yeem tig lub dav hlau-polarized lub teeb nyob rau hauv qhov zoo sib xws tab sis nyob rau hauv ntau cov lus qhia. D thiab L-isomer ntawm tyrosine uas tig lub dav hlau polarized lub teeb nyob rau hauv lub clockwise kev taw qhia yog hu ua dextrorotatory los yog d-lysine uas enantiomer yog sau npe (+). Ntawm qhov tod tes, D thiab L-isomer ntawm tyrosine uas rotates lub dav hlau polarized lub teeb nyob rau hauv lub anticlockwise kev taw qhia yog hu ua laevorotatory los yog l-tyrosine uas enantiomer yog sau npe (-). Cov no, l- thiab d- cov ntaub ntawv ntawm tyrosine yog hu ua optical isomers (Daim duab 2).
l-tyrosine yog daim ntawv ruaj khov tshaj plaws ntawm tyrosine thiab d- tyrosine yog ib hom hluavtaws ntawm tyrosine uas tuaj yeem tsim los ntawm l-tyrosine los ntawm racemization. l- tyrosine plays lub luag haujlwm tseem ceeb hauv tib neeg lub cev hauv kev sib txuas ntawm neurotransmitters, melamine, thiab cov tshuaj hormones. Kev lag luam, l-tyrosine yog tsim los ntawm cov txheej txheem microbial fermentation. Nws yog tsuas yog siv hauv kev lag luam kws tshuaj thiab khoom noj khoom haus raws li kev noj zaub mov ntxiv lossis khoom noj khoom haus ntxiv.
Qhov txawv ntawm l-tyrosine thiab Tyrosine yog dab tsi?
Tyrosine thiab l- tyrosine muaj lub cev zoo ib yam, tab sis lawv tig lub dav hlau polarized lub teeb nyob rau hauv ntau txoj kev. Yog li ntawd, l- tyrosine tej zaum yuav muaj kev sib txawv ntawm cov kab mob lom thiab ua haujlwm zoo. Txawm li cas los xij, kev tshawb fawb tsawg heev tau ua tiav txhawm rau txhawm rau paub qhov txawv ntawm cov teebmeem lom neeg thiab cov khoom ua haujlwm. Qee qhov sib txawv no yuav suav nrog,
Siab
l-tyrosine: l-cov ntaub ntawv ntawm cov amino acids raug suav tias yog tasteless, Tyrosine: d-forms nyiam muaj qab zib.
Yog li ntawd, l- tyrosine tej zaum yuav tsawg dua / tsis sweeter dua tyrosine.
Abundance
l-tyrosine: l-cov ntaub ntawv ntawm cov amino acid suav nrog l-tyrosine yog cov ntawv ntau tshaj plaws hauv cov xwm txheej. Piv txwv li, cuaj ntawm kaum cuaj L-amino acids feem ntau pom nyob rau hauv cov proteins yog dextrorotatory, thiab tus so yog levorotatory.
Tyrosine: Cov d-forms ntawm cov amino acids soj ntsuam tau pom tias tshwm sim tsis tshua muaj.
