YGangrene vs Necrosis
Necrosis thiab gangrene yog ob nqe lus ntsib hauv pathology. Txawm hais tias cov no tsis yog cov ntsiab lus feem ntau hnov ntawm cov neeg tsis yog kws kho mob, nws yuav pab tau kom nkag siab qhov sib txawv ntawm qhov tshwj xeeb yog tias qhov no tshwm sim rau koj lossis koj cov neeg koj hlub. Tom qab raug mob ntawm cov nqaij mos, cov kws kho mob yuav siv cov ntsiab lus no thaum lawv piav qhia rau koj. Lawv nyuaj heev los piav ob peb nqe lus yooj yim vim lawv yog cov txheej txheem nyuaj nrog ntau theem tseem ceeb. Yog li, cov kws kho mob siv cov ntsiab lus necrosis thiab gangrene xa mus rau tag nrho cov txheej txheem. Thawj qhov kom nkag mus rau hauv peb lub taub hau yog tias muaj ntau hom necrosis thiab gangrene yog ib hom zoo li no. Qhov txawv ntawm necrosis thiab gangrene yog, yog li ntawd, maj mam.
Necrosis
Necrosis tuaj yeem tshwm sim ncaj qha lossis tom qab cell degeneration. Cov kev hloov pauv thaum ntxov yog qhov hloov maj mam thiab tshwm sim ntawm electron microscope tsuas yog tom qab 2 mus rau 3 teev thiab hauv lub teeb tsom iav tsuas yog tom qab 6 teev. Kev hloov pauv ntawm tes tuaj yeem muab faib ua cov kev hloov pauv nuclear thiab kev hloov cytoplasmic. Cov khoom siv Nuclear tuaj yeem ua ntej clump rau hauv cov khoom hnyav, uas stain nrog cov stains yooj yim. Qhov no yog hu ua "Pyknosis". Tom qab ntawd, cov pawg no tuaj yeem tawg mus rau hauv cov khoom me me hauv cov txheej txheem hu ua "Karyorrhexis", lossis tau lysed hauv cov txheej txheem hu ua "Karyolysis". Cytoplasmic hloov pib nrog lub cytoplasm ua homogenous thiab stains nrog acidic stains. Qhov no yog vim denaturation ntawm cytoplasmic proteins. Cov organelles tshwj xeeb nqus dej thiab o. Enzymes tau tso tawm los ntawm lysosomes, thiab lub cell tawg (autolysis). Biochemically tag nrho cov kev hloov no tshwm sim nyob rau hauv kev hais kwv txhiaj nrog ib tug loj heev influx ntawm calcium ions. Muaj ntau hom necrosis. Lawv yog coagulative necrosis, liquefactive necrosis, rog necrosis, caseous necrosis, gummatous necrosis, fibrinoid necrosis thiab gangrene.
Nyob rau hauv coagulative necrosis hlwb khaws cov txheej txheem ntawm tes rau ob peb hnub thaum tag nrho lwm yam kev hloov pauv tshwm sim. Hom necrosis no feem ntau pom hauv cov khoom nruab nrog cev feem ntau tom qab cov ntshav tsis zoo. Nyob rau hauv liquefactive necrosis lub cell yog lysed kiag li; yog li tsis muaj cellular qauv. Qhov no feem ntau pom nyob rau hauv lub hlwb thiab tus txha caj qaum. Muaj ob hom rog necrosis; enzymatic thiab non-enzymatic rog necrosis. Nyob rau hauv enzymatic rog necrosis uas tshwm sim tus yam ntxwv nyob rau hauv mob pancreatitis, cell rog tau lysed mus rau hauv fatty acids thiab glycerol los ntawm pancreatic lipase thiab cov ntaub ntawv complexes nrog calcium. Yog li, qhov tsos yog chalky dawb. Non-enzymatic fat necrosis feem ntau pom nyob rau hauv cov ntaub so ntswg subcutaneous, mis thiab plab. Cov neeg mob uas tsis yog-enzymatic rog necrosis yuav luag ib txwm muab keeb kwm ntawm kev raug mob. Txawm li cas los xij, kev raug mob tsis tau qhia meej meej tias yog vim li cas. Fibrosis ua raws li cov tsis-enzymatic rog necrosis tsim cov khoom loj qee zaum tsis paub qhov txawv ntawm kev kho mob qog noj ntshav. Caseous thiab gummatous necrosis yog vim granuloma tsim tom qab kis kab mob. Fibrinoid necrosis feem ntau pom hauv cov kab mob autoimmune.
Gangrene
Gangrene yog ib lo lus siv dav, xa mus rau qhov chaw kho mob qhov chaw uas cov nqaij mos necrosis yog qhov nyuaj rau qhov sib txawv los ntawm kev kis kab mob thib ob. Muaj peb hom gangrene; qhuav, ntub thiab roj gangrene. Dry gangrene feem ntau tshwm sim ntawm qhov kawg vim cov ntshav tsis zoo uas tshwm sim los ntawm kev txhaws ntawm cov hlab ntsha. Kev ntub dej gangrene tshwm sim los ntawm cov kab mob loj heev uas ua rau cov kab mob necrosis. Nws tuaj yeem tshwm sim ntawm extremities nrog rau hauv cov kabmob sab hauv. ntub gangrene yog qhov nyuaj rau demarcate los ntawm cov ntaub so ntswg noj qab nyob zoo; Yog li ntawd, kev phais excision yog nyuaj. Cov neeg tuag nyob rau hauv ntub gangrene yog siab. Gas gangrene yog vim muaj kab mob Clostridium perfringens. Nws yog tus cwj pwm los ntawm qhov dav necrosis thiab kev tsim cov pa roj. Muaj crepitation ntawm palpation.
Qhov txawv ntawm Necrosis thiab Gangrene yog dab tsi?
• Necrosis tuaj yeem tshwm sim yam tsis muaj kab mob thaum gangrene vim yog kis kab mob necrotic.
• Gangrene feem ntau yog dav dua li lwm hom necrosis.
• Kev tuag hauv gangrene siab dua li lwm hom necrosis.
Nyeem ntxiv:
1. Qhov txawv ntawm Necrosis thiab Apoptosis
