Qhov Tseem Ceeb Qhov txawv - Coagulative vs Liquefactive Necrosis
Nyob rau hauv cov ntsiab lus ntawm cell lysis, necrosis yog ib qho tshwm sim ntawm kev raug mob ntawm tes uas ua rau autolysis, kev tuag ntxov ntxov ntawm cov hlwb sib txawv hauv cov ntaub so ntswg. Qhov no tuaj yeem tshwm sim los ntawm lwm yam xws li kev puas tsuaj rau lub cell, co toxins, thiab kab mob. Cov yam ntxwv no ua rau lub cev tsis muaj zog ntawm cov khoom sib txawv ntawm cov cell. Necrosis tsis ua raws li txoj kev taw qhia ntawm ntuj apoptosis. Cellular tuag vim necrosis tshwm sim los ntawm kev ua kom cov receptors sib txawv uas ua rau degeneration ntawm cell membranes; qhov no ua rau kev tso tawm cov khoom sib txawv ntawm cov xov tooj ntawm tes tuag rau hauv qhov chaw extracellular. Qhov no ua rau cov lus teb inflammatory uas ua rau cov leucocytes thiab phagocytes tshem tawm cov lysed thiab tuag hlwb los ntawm phagocytosis. Yog tias necrosis tsis kho, nws ua rau muaj cov ntaub so ntswg tuag thiab cov khib nyiab ntawm tes ze ntawm qhov chaw ntawm cell tuag. Necrosis tuaj yeem faib ua ntau hom. Coagulative necrosis thiab Liquefactive necrosis yog ob hom loj yog tias necrosis. Hauv coagulative necrosis, qhov degeneration ntawm cov protein fibers ua rau cov khoom tawg ntawm cov ntaub so ntswg tuag thiab qhov no suav tias yog hom mob necrosis. Liquefactive necrosis, ib hom mob ntev necrosis, ua rau kev zom cov ntaub so ntswg tuag rau hauv cov kua dej uas tau muab tshem tawm los ntawm macrophages. Qhov no yog qhov sib txawv tseem ceeb ntawm Coagulative thiab Liquefactive Necrosis.
Y Coagulative Necrosis yog dab tsi?
Coagulative necrosis tshwm sim feem ntau vim yog infarction lossis ischemia, feem ntau hauv cov ntaub so ntswg ntawm lub plawv, lub raum thiab cov qog adrenal. Cov laj thawj sab nraud rau coagulative necrosis yog kev raug mob, ntau hom co toxins thiab kuj yog vim muaj ntau yam mob ntev thiab mob tiv thaiv kab mob. Hypoxic tej yam kev mob ua rau localized cell tuag. Coagulative necrosis yog ib hom mob necrosis uas ua rau degeneration ntawm cov protein fibers, uas ua rau hloov albumin mus rau hauv ib qho opaque ruaj qauv uas xaus rau hauv ib nrab ntawm cov khoom khib nyiab. Nws kuj denatures cov qauv proteins uas ua rau inhibition ntawm proteolysis kev ua. Vim yog vim li cas saum toj no, daim ntawv coagulated los yog daim ntawv ib nrab yog tsim. Cov txheej txheem rov tsim dua tsuas yog tshwm sim yog tias muaj cov hlwb txaus nyob ib puag ncig thaj tsam necrotic. Los ntawm qhov kub thiab txias, coagulative necrosis tuaj yeem raug ntxias thiab qhov kev xav no yog siv los kho cov qog nqaij hlav cancer.
Daim duab 01: Coagulative Necrosis
Nyob rau hauv cov ntsiab lus ntawm pathology, coagulative necrosis macroscopically tshwm sim raws li ib tug daj ntseg ntawm cov ntaub so ntswg uas yog highlighted los ntawm ib puag ncig cov ntaub so ntswg uas yog heev vascularized. Cov ntaub so ntswg necrotic tuaj yeem hloov mus rau hauv liab vim yog mob. Kev tsim dua tshiab tuaj yeem ua tiav los ntawm cov hlwb uas nyob ib puag ncig yog tias muaj cov kab mob zoo-vascularized txaus. Microscopically necrotic hlwb yog pom nrog cov qauv kev puas tsuaj thiab tsis muaj nucleus thaum nws stained nrog hematoxylin thiab eosin stain.
Liquefactive Necrosis yog dab tsi?
Nyob rau hauv liquefactive necrosis, cov ntaub so ntswg tuag yog zom rau hauv cov kua loj. Qhov no feem ntau yog txuam nrog cov kab mob sib txawv, ob qho tib si fungal thiab kab mob. Thaum ib cov ntaub so ntswg ua rau liquefactive necrosis vim hydrolytic enzymes, cov ntaub so ntswg kis tau tag nrho digested. Qhov no tshwm sim nyob rau hauv tsim ntawm qhov txhab uas muaj cov kua paug, tuab opaque kua uas yog tsim los ntawm cov kab mob. Thaum cov khib nyiab ntawm tes raug tshem tawm los ntawm WBC (cov qe ntshav dawb) cov kua dej uas muaj kab noj yog sab laug. Nyob rau hauv lub hauv nruab nrab lub paj hlwb, lub paj hlwb tuag vim hypoxia tshwm sim nyob rau hauv liquefactive necrosis qhov twg tso tawm ntawm digestive enzymes los ntawm lub lysosomes hloov cov ntaub so ntswg kis mus rau hauv cov kua paug. Cov neurons muaj ntau dua ntawm lysosomes, uas ua rau cov ntaub so ntswg liquefaction. Cov txheej txheem no tsis tuaj yeem pib vim muaj cov kab mob stimulus. Qhov chaw necrotic yuav softened thiab muaj cov ntaub so ntswg necrotic khib nyiab nrog liquefied chaw. Cov cheeb tsam no yuav raug kaw nrog lub hnab kaw uas yuav ua raws li phab ntsa.
Daim duab 02: Liquefactive necrosis
Liquefactive necrosis tuaj yeem tshwm sim hauv lwm yam kabmob nrog rau lub ntsws, uas cuam tshuam rau lub ntsws cov ntaub so ntswg ua kab noj hniav. Cov kab noj hniav yog ntau tshaj 2 cm ntev. Liquefactive necrosis yog qhov ua rau tuag taus tsawg dua thaum piv nrog lwm cov txheej txheem necrosis txij li nws liquefies.
Dab tsi yog qhov zoo sib xws ntawm Coagulative thiab Liquefactive Necrosis?
Ob yam txheej txheem koom nrog hauv autolysis ntawm hlwb
Qhov txawv ntawm Coagulative thiab Liquefactive Necrosis yog dab tsi?
Coagulative vs Liquefactive Necrosis |
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| Coagulative necrosis yog hom kev tuag ntawm tes tuag feem ntau tshwm sim los ntawm ischemia lossis infarction. | Liquefactive necrosis yog hom necrosis uas ua rau hloov pauv cov ntaub so ntswg mus rau hauv cov kua dej khov. |
| feeb | |
| Coagulative necrosis yuav ua rau kev loj hlob ntawm ib nrab (coagulated) khib nyiab vim degeneration ntawm cov proteins fibers. | Liquefactive necrosis yuav zom cov ntaub so ntswg necrotic rau hauv cov kua dej, kua paug. |
| Type of Necrosis | |
| Coagulative necrosis yog chronic. | Liquefactive necrosis yog mob. |
Summary – Coagulative vs Liquefactive Necrosis
Necrosis tshwm sim vim kev puas tsuaj ntawm tes uas ua rau autolysis ntawm cov hlwb, piv txwv li, tsis muaj kev ua haujlwm ntawm tes tuag. Coagulative necrosis thiab liquefactive necrosis yog ob yam tseem ceeb ntawm necrosis. Hauv coagulative necrosis, cov ntaub so ntswg necrotic yuav tsim cov khib nyiab ib nrab vim yog degeneration ntawm cov protein fibers. Hauv liquefactive necrosis, cov ntaub so ntswg necrotic yog zom rau hauv cov kua. Qhov no yog qhov sib txawv ntawm coagulative thiab liquefactive necrosis.
Download PDF Version of Coagulative vs Liquefactive Necrosis
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li cov ntawv sau tseg. Thov download PDF version ntawm no Qhov txawv Ntawm Coagulative thiab Liquefactive Necrosis
