Aerobic vs Anaerobic Glycolysis
Glycolysis yog thawj kauj ruam ntawm kev tsim ATP uas tshwm sim hauv cytosol sab nraud ntawm mitochondria, siv cov piam thaj los ua lub zog. Nws tshwm sim hauv ob qho tib si aerobic thiab anaerobic ib puag ncig, thiab yog tib txoj hauv kev uas muaj peev xwm tsim ATP thaum tsis muaj oxygen. Yog li ntawd, nws tuaj yeem pom nyob rau hauv cov kab mob xws li prokaryotes, hlwb zoo li erythrocytes, thiab nyob rau hauv ib puag ncig hypoxic xws li kev cog lus sai sai ntawm cov leeg nqaij lossis cov ntaub so ntswg ischemic uas tsis muaj mitochondria. Cov txheej txheem ntawm glycolysis tuaj yeem muab faib ua aerobic lossis anaerobic glycolysis, nyob ntawm seb muaj cov pa oxygen ntawm ib puag ncig nws tshwm sim. Txawm li cas los xij, hauv ob txoj kev, qhov pib yog qabzib thiab cov khoom kawg yog pyruvate.
(Image Source: “Anaerobic vs. Aerobic pathways” SparkNotes.com. SparkNotes LLC. n.d. Web. 13 Sept. 2013.)
Aerobic Glycolysis
Aerobic glycolysis yog txoj hauv kev glycolytic uas tshwm sim hauv cytosol nyob rau hauv muaj oxygen. Thaum piv rau anaerobic glycolysis, txoj hauv kev no muaj txiaj ntsig zoo dua thiab ua rau ATP ntau dua rau cov piam thaj molecule. Hauv aerobic glycolysis, cov khoom kawg, pyruvate raug xa mus rau mitochondria rau kev pib ntawm Citric acid voj voog. Yog li ntawd, cov khoom zoo tshaj plaws ntawm aerobic glycolysis yog 34 ATP molecules, dej, thiab carbon dioxide.
Anaerobic Glycolysis
Anaerobic glycolysis tshwm sim hauv cytoplasm thaum lub cell tsis muaj oxygenated ib puag ncig lossis tsis muaj mitochondria. Hauv qhov no, NADH yog oxidized rau NAD + hauv cytosol los ntawm kev hloov pyruvate rau lactate. Anaerobic glycolysis tsim tawm (2 lactate + 2 ATP + 2 H2O + 2 H +) los ntawm ib qho qabzib molecule. Tsis zoo li aerobic glycolysis, anaerobic glycolysis tsim lactate, uas txo cov pH thiab inactivates cov enzymes.
Qhov txawv ntawm Aerobic thiab Anaerobic Glycolysis yog dab tsi?
• Aerobic glycolysis tshwm sim hauv cov cheeb tsam uas muaj cov pa oxygen, whereas anaerobic glycolysis tshwm sim hauv qhov chaw tsis muaj oxygen.
• Aerobic glycolysis ua haujlwm zoo dua li anaerobic glycolysis; yog li nws tsim ATP ntau dua li anaerobic glycolysis.
• Aerobic glycolysis tshwm sim tsuas yog hauv eukaryotes thaum anaerobic glycolysis tshwm sim hauv ob qho tib si prokaryotes thiab eukaryotes.
• Tsis zoo li hauv anaerobic glycolysis, qhov kawg khoom ntawm Aerobic glycolysis (pyruvate) yog siv los pib lwm txoj hauv kev hauv mitochondria.
• Anaerobic glycolysis tsim 2ATPs rau ib cov piam thaj molecule thaum aerobic glycolysis tsim 36 mus rau 38 ATPs ib cov piam thaj molecule.
• Cov khoom kawg kawg ntawm anaerobic glycolysis yog lactate, uas tej zaum yuav ua mob rau lub cell nws tus kheej, whereas ntawm aerobic glycolysis yog dej thiab carbon dioxide, uas tsis muaj teeb meem rau lub hlwb.
• Tsis zoo li hauv anaerobic glycolysis, NADH + H + raug oxidative phosphorylation nyob rau hauv muaj cov pa oxygen hauv aerobic glycolysis.
• Pyruvate txo qis rau lactate thaum lub sij hawm anaerobic glycolysis whereas, thaum lub sij hawm aerobic glycolysis, pyruvate yog oxidation rau acetyl coenzyme A (acetyl-CoA).
