Hemoglobin vs Myoglobin
Myoglobin thiab hemoglobin yog hemoproteins uas muaj peev xwm khi cov pa oxygen molecular. Cov no yog thawj cov proteins uas muaj nws cov qauv peb-dimensional daws los ntawm X-ray crystallography. Proteins yog cov polymers ntawm cov amino acids, koom nrog peptide bonds. Amino acids yog lub tsev blocks ntawm cov proteins. Raws li lawv cov duab tag nrho, cov proteins no tau categorized nyob rau hauv globular proteins. Globular proteins muaj me ntsis kheej kheej los yog ellipsoidal duab. Cov khoom sib txawv ntawm cov protein globular tshwj xeeb no pab lub cev hloov cov pa oxygen molecules ntawm lawv. Qhov chaw nquag ntawm cov protein tshwj xeeb no muaj cov hlau (II) protoporphyrin IX encapsulated nyob rau hauv lub hnab ntim dej resistant.
Myoglobin
Myoglobin tshwm sim raws li cov protein monomeric uas lub globin nyob ib puag ncig heme. Nws ua raws li tus neeg nqa khoom nruab nrab ntawm cov pa oxygen hauv cov leeg nqaij. Thaum cov leeg nqaij ua haujlwm, lawv xav tau ntau cov pa oxygen. Cov leeg nqaij siv cov proteins no kom nrawm oxygen diffusion thiab noj oxygen rau lub sijhawm ua pa hnyav. Cov qauv tertiary ntawm myoglobin zoo ib yam li cov qauv dej soluble globule protein.
Polypeptide saw ntawm myoglobin muaj 8 cais txoj cai α-helices. Txhua cov protein molecule muaj ib pawg heme prothetic thiab txhua heme residue muaj ib lub hauv paus kev sib koom ua ke ntawm cov hlau atom. Oxygen yog khi ncaj qha rau cov hlau atom ntawm pawg heme prosthetic.
Hemoglobin
Hemoglobin tshwm sim raws li tetrameric protein nyob rau hauv txhua lub subunit muaj ib tug globin nyob ib ncig ntawm ib heme. Nws yog lub system-wide carrier ntawm oxygen. Nws khi cov pa oxygen molecules thiab tom qab ntawd nws raug thauj los ntawm cov ntshav los ntawm cov qe ntshav liab.
Nyob rau hauv vertebrates, oxygen yog diffused los ntawm lub ntsws cov ntaub so ntswg mus rau hauv cov ntshav liab. Txij li thaum hemoglobin yog tetramer, nws tuaj yeem khi plaub oxygen molecules ib zaug. Tom qab ntawd cov pa oxygen raug muab faib los ntawm tag nrho lub cev thiab tawm ntawm cov qe ntshav liab mus rau cov hlwb ua pa. Tom qab ntawd hemoglobin coj cov pa roj carbon dioxide thiab xa rov qab mus rau lub ntsws. Yog li, hemoglobin pab xa cov pa oxygen xav tau rau cov cellular metabolism thiab tshem tawm cov khoom pov tseg, carbon dioxide.
hemoglobin muaj ntau cov saw hlau polypeptide. Tib neeg hemoglobin yog tsim los ntawm ob α (alpha) thiab ob β (beta) subunits. Txhua α-subunit muaj 144 residues, thiab txhua β-subunit muaj 146 residues. Cov yam ntxwv ntawm ob qho tib si α (alpha) thiab β (beta) subunits zoo ib yam li myoglobin.
Hemoglobin vs Myoglobin
• Hemoglobin thauj oxygen hauv cov ntshav thaum myoglobin thauj lossis khaws cov pa oxygen hauv cov leeg.
• Myoglobin muaj ib leeg polypeptide saw thiab hemoglobin muaj ob peb polypeptide chains.
• Tsis zoo li cov myoglobin, qhov concentration ntawm hemoglobin hauv cov qe ntshav liab yog siab heev.
• Thaum pib, myoglobin khi cov pa oxygen molecules yooj yim heev thiab tsis ntev los no saturated. Cov txheej txheem khi no nrawm heev hauv myoglobin dua li hauv hemoglobin. Hemoglobin pib khi oxygen nrog nyuaj.
• Myoglobin tshwm sim raws li cov protein monomeric thaum hemoglobin tshwm sim raws li tetrameric protein.
• Ob hom polypeptide chains (ob α-chains thiab ob β- chains) muaj nyob hauv hemoglobin.
• Myoglobin tuaj yeem khi ib lub molecule oxygen hu ua monomer, thaum hemoglobin tuaj yeem khi plaub lub molecules oxygen, thiaj li hu ua tetramer.
• Myoglobin khi oxygen nruj dua li hemoglobin.
• Hemoglobin tuaj yeem khi thiab tawm ob qho tib si oxygen thiab carbon dioxide, tsis zoo li cov myoglobin.
