Qhov sib txawv tseem ceeb ntawm bacitracin thiab Neosporin yog tias bacitracin tuaj yeem nres cov kab mob loj hlob, qhov Neosporin tuaj yeem nres cov kab mob loj hlob thiab tua cov kab mob uas twb muaj lawm.
Bacitracin thiab Neosporin tuaj yeem ua haujlwm ntawm daim tawv nqaij ua cov tshuaj pleev ib ce los tiv thaiv lossis kho cov kab mob ntawm daim tawv nqaij. Txawm li cas los xij, lawv ua haujlwm sib txawv ntawm ib leeg.
Bacitracin yog dab tsi?
Bacitracin yog polypeptide muaj cov tshuaj formula C66H103N17O 16S. Nws yog ib qho tshuaj tua kab mob polypeptide thiab tuaj yeem pom tau los ntawm kev sib xyaw ntawm cov kab mob sib txuas uas tsim los ntawm cov kab mob Bacillus licheniformis. Cov kab mob no tau raug cais tawm thawj zaug los ntawm ntau yam Tracy I hauv xyoo 1945. Cov peptide no tuaj yeem cuam tshuam cov kab mob Gram-zoo los ntawm kev cuam tshuam nrog cov phab ntsa ntawm tes thiab peptidoglycan synthesis. Ntxiv mus, nws yog feem ntau ua raws li kev npaj tshuaj pleev ib ce vim tias nws tuaj yeem ua rau lub raum puas thaum siv los ua tshuaj. Qee lub ntsiab lus rau bacitracin suav nrog bacitracin A, bacitracin A2a, Baciguent, Fortracin, Bacitracinum, thiab lwm yam.
Thaum xav txog cov tshuaj ntawm cov tshuaj no, nws yog homodetic cyclic peptide muaj li ntawm (4R)-2-[(1S, 2S)-1-amino-2-methylbutyl]-4, 5-dihydro-1, 3-thiazole-4-carboxylic acid. Cov kua qaub no txuas rau hauv lub taub hau-rau-tus qauv rau leucyl, D-glutamyl, L-lysyl, D-ornityl, L-isoleucyl, D-phenylalanyl, L-histidyl. Ntxiv mus, nws muaj D-aspartyl thiab L-asparaginyl residues uas tau ua ke ua ke thiab cyclized los ntawm condensation ntawm sab-chain amino pawg ntawm L-lysyl residue nrog C-terminal carboxylic acid pawg.
Cov molar loj ntawm bacitracin yog 1422.7 g / mol. Nws muaj hydrogen daim ntawv cog lus pub suav ntawm 17 thiab hydrogen daim ntawv lees txais suav ntawm 21. Tsis tas li ntawd, bacitracin muaj cov nyiaj sib hloov ntawm 31. Nws muaj qhov nyuaj ntawm 2850 degrees thiab muaj 15 qhov chaw stereocenter. Bacitracin tshwm sim nyob rau hauv ib qho khoom hauv lub xeev ntawm chav tsev kub thaum lub melting point nyob rau hauv thaj tsam ntawm 221 - 225 degrees Celsius. Nws yog dawb do soluble nyob rau hauv dej.
Cov tshuaj no yog qhia nyob rau hauv cov tshuaj pleev ib ce rau mob thiab mob nyob rau hauv daim tawv nqaij kab mob. Qee zaum, nws yog siv intramuscularly rau infantile streptococcal pneumonia thiab empyema. Ntxiv mus, nws yog formulated raws li ib tug tshuaj pleev nrog neomycin thiab polymyxin B raws li ib tug over-the-counter tshuaj.
Neosporin yog dab tsi?
Neosporin yog ib hom tshuaj uas muaj cov tshuaj formula C
23H46N6O 13Nws muaj txiaj ntsig zoo hauv kev tiv thaiv thiab kho cov kab mob me me uas tshwm sim los ntawm kev txiav me me, khawb, lossis hlawv. Cov tshuaj no muaj nyob rau ntawm lub txee rau tus kheej noj tshuaj. Txawm li cas los xij, nws yuav tsum tsis txhob siv ntau qhov chaw ntawm lub cev vim tias nws tuaj yeem ua rau tawv nqaij raug mob thiab kis kab mob. Cov khoom tseem ceeb ntawm Neosporin muaj xws li neomycin, bacitracin, polymyxin, thiab tshuaj tua kab mob uas tuaj yeem ua haujlwm los ntawm kev txwv kev loj hlob ntawm cov kab mob. Txawm li cas los xij, nws tsuas yog tiv thaiv lossis kho cov kab mob ntawm daim tawv nqaij. Yog li ntawd, nws tsis tuaj yeem ua haujlwm tawm tsam lwm hom kab mob, xws li kab mob los ntawm cov kab mob fungi thiab kab mob. Kev siv tsis tsim nyog tuaj yeem ua rau qis dua.
Muaj qee qhov kev mob tshwm sim, xws li lwm hom kab mob ntawm daim tawv nqaij. Txawm li cas los xij, qhov no feem ntau yog ib qho tshuaj tiv thaiv zoo. Qee qhov kev ua xua tuaj yeem tshwm sim, xws li pob liab liab, kub hnyiab, khaus, o, kiv taub hau, thiab lwm yam.
Neomycin ua rau feem ntau ntawm Neosporin. Nws muaj cov tshuaj formula C23H46N6O13thiab nws cov molar mass 614.6 g/mol. Nws muaj hydrogen daim ntawv cog lus pub suav ntawm 13, thiab cov hydrogen daim ntawv lees txais suav yog 19. Lub rotatable bond suav yog 9. Qhov nyuaj ntawm qhov sib xyaw no tuaj yeem txhais tau tias yog 872 degrees. Ntxiv mus, lub atom stereocenter suav suav yog 19. Feem ntau, cov khoom no tshwm sim nyob rau hauv cov kua hauv lub xeev ntawm chav tsev kub, thiab lub melting point yog tsawg heev piv (6 degrees Celsius) /. Nws yog soluble hauv dej thiab ntau lwm cov kuab tshuaj xws li methanol. Tsis tas li ntawd, nws yog hygroscopic tshuaj.
Qhov txawv ntawm Bacitracin thiab Neosporin yog dab tsi?
Bacitracin thiab Neosporin yog ob hom tshuaj pleev ib ce uas siv los kho cov kab mob ntawm daim tawv nqaij. Qhov sib txawv tseem ceeb ntawm bacitracin thiab Neosporin yog tias bacitracin tuaj yeem tiv thaiv kev loj hlob ntawm cov kab mob, thaum Neosporin tuaj yeem nres cov kab mob loj hlob thiab tua cov kab mob uas twb muaj lawm. Ntxiv mus, Neosporin tuaj yeem tawm tsam ntau hom kab mob, thaum bacitracin tsis tuaj yeem tawm tsam ntau yam xws li Neosporin.
Cov duab hauv qab no nthuav tawm qhov sib txawv ntawm bacitracin thiab Neosporin hauv daim ntawv teev npe rau kev sib piv ntawm ib sab.
Summary – Bacitracin vs Neosporin
Bacitracin thiab Neosporin yog cov tshuaj tseem ceeb rau cov kab mob ntawm daim tawv nqaij uas siv los ua cov tshuaj pleev xim. Qhov sib txawv tseem ceeb ntawm bacitracin thiab Neosporin yog tias bacitracin tuaj yeem nres cov kab mob loj hlob, thaum Neosporin tuaj yeem nres cov kab mob loj hlob thiab tua cov kab mob uas twb muaj lawm.
