Qhov sib txawv tseem ceeb ntawm CLL thiab SLL yog tias CLL yog hom Non-Hodgkin's lymphoma qhov twg B hlwb txawv txav feem ntau hauv cov ntshav thiab cov pob txha, thaum SLL yog hom Non-Hodgkin's lymphoma qhov twg B hlwb txawv txav. feem ntau hauv cov qog ntshav qog ntshav.
Lymphoma yog mob qog noj ntshav uas pib los ntawm kev kis cov lymphocytes, sib ntaus sib tua ntawm lub cev tiv thaiv kab mob hu ua. Cov hlwb no nyob hauv cov qog nqaij hlav, spleen, thymus, pob txha pob txha, thiab lwm qhov ntawm lub cev. Feem ntau, hauv lymphoma, cov lymphocytes hloov pauv thiab loj hlob tawm ntawm kev tswj hwm. Muaj ob hom lymphomas: Non-Hodgkin thiab Hodgkin. CLL thiab SLL yog ob hom Non-Hodgkin hom lymphomas.
CLL (Chronic Lymphocytic Leukemia) yog dab tsi?
Chronic lymphocytic leukemia (CLL) yog mob qog noj ntshav thiab pob txha pob txha. Hauv CLL, cov hlwb B txawv txav feem ntau hauv cov ntshav thiab cov pob txha. Lub sij hawm mob nyob rau hauv mob lymphocytic leukemia los ntawm qhov tseeb tias tus kab mob no feem ntau mus qeeb dua. Lub sij hawm lymphocytic qhia txog hom hlwb feem ntau cuam tshuam (ib pawg ntawm cov qe ntshav dawb hu ua lymphocytes). CLL feem ntau cuam tshuam rau cov neeg laus, thiab nws yog hom Non-Hodgkin lymphoma.
Ntau tus neeg uas kuaj tau CLL tsis muaj tsos mob thaum xub thawj. Cov tsos mob thiab cov tsos mob ntawm CLL tej zaum yuav muaj xws li cov qog nqaij hlav loj thiab tsis mob, qaug zog, ua npaws, mob nyob rau sab laug sab laug ntawm lub plab (vim qhov loj spleen), hmo ntuj tawm hws, poob phaus, los ntshav thiab bruising yooj yim dua, kub siab, anemia, ua tsis taus pa luv, tawv nqaij daj, thiab nquag kis.
Daim duab 01: CLL
Feem ntau, qhov tseeb ntawm CLL tsis paub. Tab sis feem ntau tej zaum, nws yog vim muaj kev hloov pauv ntawm DNA ntawm cov hlwb tsim cov ntshav. Nws muaj feem yuav ua raws li cov kev pheej hmoo xws li tsev neeg keeb kwm ntawm CLL, cov hnub nyoog nruab nrab lossis laus dua, cov txiv neej dawb, thiab cov txheeb ze uas yog cov neeg Yudais sab hnub tuaj lossis Lavxias teb sab.
Ntxiv mus, CLL tuaj yeem kuaj tau los ntawm kev kuaj ntshav, kuaj cov duab xws li CT scans thiab PET scans, pob txha pob txha biopsies, lymph nodes biopsies, thiab kuaj caj ces. Tsis tas li ntawd, cov kev kho mob rau CLL muaj xws li kev kho mob (fludarabine, rituximab), radiotherapy, stem cells lossis pob txha pob txha hloov, kev phais kom tshem tawm cov poov xab o, tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tiv thaiv kab mob kom txo tau cov kab mob, hloov ntshav, immunoglobulin hloov kho, thiab txhaj tshuaj. hu ua granulocyte stimulating factor (G-CSF) los pab txhawb cov qe ntshav dawb.
SLL (Small Lymphocytic Lymphoma) yog dab tsi?
Small lymphocytic lymphoma (SLL) yog ib hom Non-Hodgkin's lymphoma qhov twg B hlwb txawv txav feem ntau hauv cov qog ntshav. Nws kuj yog mob qog noj ntshav qeeb. Tus mob no cuam tshuam rau txiv neej ntau dua li poj niam. SLL feem ntau pom hauv cov neeg laus (qhov nruab nrab hnub nyoog kuaj pom yog 65). Cov tsos mob ntawm SLL yuav muaj xws li tsis mob o ntawm caj dab, caj dab, thiab puab tais, qaug zog, poob phaus, ua npaws, hmo ntuj tawm hws, o, mob plab, hnov zoo tag nrho, ua tsis taus pa, yooj yim bruising, thiab daim tawv nqaij mob.
Qhov laj thawj ntawm SLL tsis paub. Nws tuaj yeem yog vim DNA hloov pauv ntawm cov qe ntshav tsim. Cov xwm txheej txaus ntshai rau SLL suav nrog cov hnub nyoog laus dua, tsev neeg keeb kwm, lub cev tsis muaj zog tiv thaiv kab mob (HIV), kev siv tshuaj kho mob yav dhau los, raug rau cov tshuaj tua kab ntev ntev, thiab raug radon hauv tsev.
Daim duab 02: SLL
Ntxiv mus, SLL tuaj yeem kuaj tau los ntawm kev kuaj lub cev, qog nqaij hlav qog nqaij hlav, thiab kuaj pob txha pob txha xws li (pob txha pob txha aspiration thiab biopsy). Tsis tas li ntawd, SLL tuaj yeem kho nrog kev kho mob, kev kho mob monoclonal antibody (alemtuzumab, brentuximab, ibritumomab tiuxetan, obinutuzumab), kev kho hluav taws xob, kev kho tshuaj tsom (acalabrutinib, ibrutinib, duvelisib, idelalisib), thiab qia cell.
Dab tsi yog qhov zoo sib xws ntawm CLL thiab SLL?
- CLL thiab SLL yog ob hom qog ntshav ntshav.
- Lawv yog hom tsis-Hodgkin lymphomas.
- Hauv ob hom mob qog noj ntshav, B hlwb raug cuam tshuam.
- Ob leeg mob qog noj ntshav feem ntau yog vim muaj kev hloov pauv hauv DNA ntawm cov hlwb tsim cov ntshav.
- Lawv qeeb qeeb.
- Ob leeg mob qog noj ntshav feem ntau cuam tshuam rau cov neeg laus.
- Lawv kho tau los ntawm kev siv tshuaj khomob, hluav taws xob, thiab kev kho qia cell.
Qhov txawv ntawm CLL thiab SLL yog dab tsi?
CLL yog ib hom Non-Hodgkin's lymphoma uas txawv txav B hlwb feem ntau nyob rau hauv cov ntshav thiab cov pob txha pob txha, thaum SLL yog hom Non-Hodgkin's lymphoma qhov twg B hlwb txawv txav feem ntau hauv cov qog ntshav. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm CLL thiab SLL. Tsis tas li ntawd, tus neeg uas muaj CLL yuav muaj ntau dua 5000 monoclonal lymphocytes ib cubic millimeter (mm3). Ntawm qhov tod tes, tus neeg uas muaj SLL yuav muaj tsawg dua 5000 monoclonal lymphocytes ib cubic millimeter (mm3).
Cov lus hauv qab no qhia txog qhov sib txawv ntawm CLL thiab SLL.
Summary – CLL vs SLL
CLL thiab SLL yog ob hom Non-Hodgkin hom lymphomas. Hauv CLL, cov hlwb B txawv txav feem ntau nyob hauv cov ntshav thiab cov pob txha pob txha, thaum nyob hauv SLL, cov hlwb B txawv txav feem ntau nyob hauv cov qog ntshav. Yog li, qhov no yog cov ntsiab lus ntawm qhov sib txawv ntawm CLL thiab SLL.
