Qhov sib txawv tseem ceeb ntawm BALT GALT thiab MALT yog tias BALT yog nyob rau hauv lub bronchial submucosa thaum GALT nyob rau hauv lub mucosa, submucosa, thiab lamina propria ntawm txoj hnyuv me, thiab MALT yog nyob rau hauv ntau submucosal membrane qhov chaw ntawm lub cev.
Lymphoid cov ntaub so ntswg yog ib hom ntaub so ntswg uas ua rau cov lymphatic system, uas nyob rau hauv lem txhawb kev tiv thaiv ntawm lub cev. Cov ntaub so ntswg lymphoid feem ntau koom nrog kev tiv thaiv lub cev los ntawm cov kab mob sib txawv uas ua rau cov kab mob nkag mus, nqus cov rog los ntawm txoj hnyuv, tswj cov kua dej sib npaug ntawm lub cev, thiab tshem tawm cov khib nyiab ntawm tes. Nyob ntawm qhov chaw ntawm cov ntaub so ntswg lymphoid, nws muaj ntau hom. BALT, GALT, thiab MALT yog peb hom.
Dab tsi yog BALT (Bronchus Associated Lymphoid Tissue)?
BALT sawv cev rau bronchus txuam nrog lymphoid cov ntaub so ntswg, uas yog tertiary lymphoid qauv. BALT yog ib qho subcategory ntawm mucosa-associated lymphoid cov ntaub so ntswg. BALT muaj nyob rau hauv lub ntsws thiab bronchus thiab muaj cov lymphoid follicles. BALT feem ntau tshwm sim nyob rau hauv lub bifurcation ntawm lub Upper bronchi hauv qab lub epithelium. Nws feem ntau yog nyob nruab nrab ntawm cov hlab ntsha thiab bronchus. Nws yog ib qho chaw zoo priming rau ob qho tib si systemic thiab mucosal tiv thaiv kab mob. Cov qauv ntawm BALT zoo ib yam li ntau hom tsiaj. Tab sis qhov inducibility thiab txij nkawm txawv ntawm kab mob mus rau kab mob. Nyob rau hauv luav thiab npua, BALT yog ib yam khoom nyob rau hauv lub ntsws thiab bronchus. Tab sis nyob rau hauv cov nas thiab tib neeg, BALT tshwm tsuas yog tom qab mob los yog kis kab mob. Li no, nws yog hu ua inducible BALT los yog iBALT.
Daim duab 01: iBALT ntawm nas
Txoj kev ua haujlwm tseeb ntawm BALT hauv tib neeg tseem tsis tau qhia meej meej txij li thaum tsim cov tshuaj tiv thaiv kab mob tsis paub meej. Tab sis qhov kev ua haujlwm dav dav ntawm BALT yog los tiv thaiv lub ntsws thiab bronchus los ntawm cov kab mob nkag mus.
GALT (Gut Associated Lymphoid Tissue) yog dab tsi?
GALT sawv cev rau cov kab mob qog nqaij hlav hauv plab thiab yog lwm yam subcategory ntawm mucosa-sociated lymphoid cov ntaub so ntswg. GALT muaj nyob thoob plaws hauv cov hnyuv. GALT muaj cov neeg coob ntawm cov ntshav plasma thiab ua rau li 70% ntawm lub cev tiv thaiv kab mob los ntawm qhov hnyav. Yog li ntawd, GALT yog ib qho tseem ceeb ntawm lub cev tiv thaiv kab mob los tawm tsam cov kab mob uas tau los ntawm txoj hnyuv. Yog li, GALT cuam tshuam rau lub zog ntawm tag nrho lub cev tiv thaiv kab mob. Hauv txoj hnyuv, GALT tau sib cais los ntawm txoj hnyuv lumen thiab nws cov ntsiab lus los ntawm txoj hnyuv mucosa uas npog los ntawm txheej txheej ntawm cov hlwb epithelial. Hauv cov hnyuv me, GALT suav nrog Peyer thaj ua rau thaj. Nws yog cov ntaub so ntswg sib xyaw lymphoid nkag mus rau lub lumen thiab ua qhov chaw tseem ceeb rau kev pib ntawm kev tiv thaiv kab mob hauv plab.
Dab tsi yog MALT (Mucosa Associated Lymphoid Tissue)?
MALT sawv cev rau mucosa txuam nrog lymphoid cov ntaub so ntswg, uas yog ib tug diffuse system ntawm lymphoid cov ntaub so ntswg nyob rau hauv txawv submucosal membrane qhov chaw ntawm lub cev. Cov chaw no muaj xws li kab mob plab, nasopharynx, ntsws, thyroid, qog qaub ncaug, qhov muag, thiab tawv nqaij. Lymphocytes xws li T hlwb, B hlwb, macrophages, thiab plasma hlwb muaj ntau nyob rau hauv MALT. Tag nrho cov lymphocytes ntes cov antigens uas dhau los ntawm cov mucosal epithelium los tsim cov tshuaj tiv thaiv kab mob uas tsim nyog. 50% ntawm cov ntaub so ntswg lymphoid hauv tib neeg lub cev yog suav nrog MALT.
Daim duab 02: MALT Lymphoid Tissue
Kev faib tawm ntawm MALT suav nrog cov kab mob qog nqaij hlav hauv plab (GALT), bronchus-associated lymphoid cov ntaub so ntswg (BALT), nasal-associated lymphoid cov ntaub so ntswg (NALT), conjunctival-associated lymphoid cov ntaub so ntswg (CALT), larynx txuam nrog lymphoid cov ntaub so ntswg (LALT), daim tawv nqaij sib txuas nrog lymphoid cov ntaub so ntswg (SALT), thiab lwm yam. Lub luag haujlwm ntawm MALT yog tswj hwm mucosal tiv thaiv kab mob.
Dab tsi yog qhov zoo sib xws ntawm BALT GALT thiab MALT?
- BALT, GALT, thiab MALT yog cov ntaub so ntswg lymphatic.
- Lawv belongs rau lymphatic system.
- Ntxiv mus, tag nrho cov ntaub so ntswg cuam tshuam nrog kev tsim cov tshuaj tiv thaiv kab mob.
- BALT, GALT, thiab MALT ntxiv dag zog rau kev tiv thaiv kab mob.
- Tag nrho peb yog tam sim no nyob rau hauv cov kab rau cov chaw tshwj xeeb nyob ib ncig ntawm lub cev.
Qhov txawv ntawm BALT GALT thiab MALT yog dab tsi?
BALT yog cov qauv lymphoid tertiary uas yog ib pawg ntawm cov ntaub so ntswg mucosa-koom nrog cov qog nqaij hlav nyob hauv bronchial submucosa, thaum GALT yog ib pawg ntawm cov ntaub so ntswg mucosa-associated lymphoid uas muaj nyob thoob plaws hauv cov hnyuv, thiab MALT. yog ib qho kab mob sib kis ntawm cov ntaub so ntswg lymphoid tam sim no nyob rau hauv ntau qhov submucosal membrane ntawm lub cev. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm BALT GALT thiab MALT. Lub luag haujlwm ntawm BALT yog los tiv thaiv lub ntsws thiab cov hlab ntsws los ntawm cov kab mob nkag mus, thaum lub luag haujlwm ntawm GALT yog los tiv thaiv lub cev los ntawm cov kab mob hauv plab. Hauv qhov sib piv, txoj haujlwm ntawm MALT yog los tswj kev tiv thaiv mucosal.
Cov hauv qab no qhia txog qhov sib txawv ntawm BALT GALT thiab MALT hauv daim ntawv teev npe rau ib sab ntawm kev sib piv.
Summary – BALT vs GALT vs MALT
Lymphoid cov ntaub so ntswg txhawb kev tiv thaiv kab mob hauv lub cev. BALT, GALT, thiab MALT yog peb cov ntaub so ntswg lymphoid. BALT muaj nyob rau hauv lub ntsws thiab bronchus thiab muaj cov lymphoid follicles. Nws yog ib qho chaw zoo priming rau ob qho tib si systemic thiab mucosal tiv thaiv kab mob. GALT muaj nyob thoob plaws hauv cov hnyuv. GALT muaj cov neeg coob ntawm cov ntshav plasma thiab ua rau li 70% ntawm lub cev tiv thaiv kab mob los ntawm qhov hnyav. MALT yog ib qho kab mob sib kis ntawm cov ntaub so ntswg lymphoid tam sim no nyob rau hauv qhov sib txawv submucosal membrane ntawm lub cev. Lub luag haujlwm ntawm MALT yog los tswj kev tiv thaiv mucosal. Yog li, qhov no qhia txog qhov sib txawv ntawm BALT GALT thiab MALT.
