Qhov sib txawv tseem ceeb ntawm methylcobalamin thiab adenosylcobalamin yog methylcobalamin tsom rau kev tswj hwm qib homocysteine zoo, hos adenosylcobalamin tsom rau kev tsim lub zog thiab metabolization vim nws ua haujlwm feem ntau hauv mitochondria.
Feem ntau, cyanocobalamin yog ib qho kev kawm zoo thiab txhim khu kev qha tab sis pheej yig ntawm vitamin B12. Txawm li cas los xij, nws muaj cov molecule ntawm cyanide. Yog li ntawd, nws yog physiologically inconsequential rau tib neeg. Muaj ntau txoj hauv kev uas tau txhawb nqa los ntawm cov kws kho mob thiab cov tuam txhab ntxiv. Cov no yog coenzyme cov ntaub ntawv ntawm vitamin B12 thiab yog hu ua methylcobalamin thiab adenosylcobalamin. Ntxiv mus, peb tuaj yeem pom plaub yam loj ntawm cov vitamin B12 uas txawv ntawm ib leeg raws li pawg sab. Cov no yog adenosylcobalamin, cyanocobalamin, hydroxocobalamin, thiab methylcobalamin.
Methylcobalamin yog dab tsi?
Methylcobalamin yog ib daim ntawv ntawm cov vitamin B12 uas tsom rau kev tswj cov qib homocysteine zoo. Cov molecule no yuav luag zoo ib yam rau cyanocobalamin, tab sis muaj qhov sib txawv me ntsis ntawm lawv. Nws muaj ib tug cob alt ion uas nyob ib ncig ntawm lub nplhaib corrin. Methylcobalamin tshwj xeeb muaj ib pawg methyl txuas nrog cob alt ion. Ntxiv mus, cov tshuaj no yog ib tug tshwm sim ntawm cov vitamin B12, whereas cyanocobalamin tsis tuaj yeem nrhiav tau lawm thiab yog ib hom hluavtaws ntawm vitamin B12. Tsis tas li ntawd, peb tuaj yeem tau txais methylcobalamin los ntawm cov tshuaj ntxiv nrog rau cov khoom noj xws li ntses, qe, nqaij, thiab mis nyuj.
Daim duab 01: Cov Qauv Tshuaj ntawm Methylcobalamin
Ntxiv mus, cyanocobalamin tuaj yeem hloov mus rau methylcobalamin (lossis qee zaum mus rau hauv adenosylcobalamin) tom qab nkag mus rau hauv lub cev. Methylcobalamin yog qhov tseem ceeb rau ntau cov txheej txheem hauv lub cev. Piv txwv li, nws tuaj yeem koom nrog hauv cov metabolism hauv cov rog thiab cov amino acids. Nws tseem tuaj yeem pab tsim cov myelin, uas tuaj yeem tsim kev tiv thaiv los ntawm cov paj hlwb.
Adenosylcobalamin yog dab tsi?
Adenosylcobalamin yog ib daim ntawv ntawm cov vitamin B12 uas tsom rau kev tsim lub zog thiab metabolization vim nws ua haujlwm feem ntau hauv mitochondria. Technically, cov molecule no hu ua 5'-deoxy-5'-adenosylcobalamin. Txawm li cas los xij, nws tseem hu ua dibencozide, cobamine, thiab cobinamide.
Daim duab 2: Cov Qauv Tshuaj ntawm Adenocylcobalamin
Tsis tas li ntawd, qhov sib xyaw no tuaj yeem koom nrog hauv kev sib kho 1, 2-carbon skeleton rearrangements raws li cofactor. Tsis tas li ntawd, ib qho enzyme uas siv adenosylcobalamin ua cofactor yog methylmalonyl-CoA mutase.
Qhov txawv ntawm Methylcobalamin thiab Adenosylcobalamin yog dab tsi?
Methylcobalamin thiab adenosylcobalamin yog ob hom vitamin B12. Qhov sib txawv tseem ceeb ntawm methylcobalamin thiab adenosylcobalamin yog tias methylcobalamin tsom rau kev tswj hwm qib homocysteine zoo, thaum adenosylcobalamin tsom rau kev tsim lub zog thiab metabolization vim nws ua haujlwm feem ntau hauv mitochondria. Ntxiv mus, cov qauv tshuaj ntawm methylcobalamin thiab adenosylcobalamin muaj kev sib raug zoo rau ib leeg. Qhov tseeb, pawg sab uas txuas nrog cob alt cation hauv methylcobalamin yog ib pawg methyl, thaum adenosylcobalamin muaj cov pab pawg adenosine.
Hauv qab no yog cov ntsiab lus ntawm qhov sib txawv ntawm methylcobalamin thiab adenosylcobalamin hauv daim ntawv tabular rau ib sab sib piv.
Summary – Methylcobalamin vs Adenosylcobalamin
Raws li cov pab pawg sab nraud, muaj plaub yam loj ntawm cov vitamin B12 uas txawv ntawm ib leeg. Cov no yog adenosylcobalamin, cyanocobalamin, hydroxocobalamin, thiab methylcobalamin. Hauv kev xaus, qhov sib txawv tseem ceeb ntawm methylcobalamin thiab adenosylcobalamin yog tias methylcobalamin tsom rau kev tswj hwm qib homocysteine zoo, thaum adenosylcobalamin tsom rau kev tsim lub zog thiab metabolization vim nws ua haujlwm feem ntau hauv mitochondria.
