Qhov sib txawv tseem ceeb ntawm nicotinamide adenine dinucleotide thiab nicotinamide riboside yog nicotinamide adenine dinucleotide (NAD) yog coenzyme hauv nruab nrab rau cov metabolism uas pom nyob hauv txhua lub hlwb, thaum nicotinamide riboside (niagen) yog lwm hom vitamin B3. uas yog ua haujlwm raws li qhov ua ntej rau nicotinamide adenine dinucleotide.
Metabolism yog txheej txheem uas lub cev hloov khoom noj rau lub zog. Thaum lub sijhawm ua haujlwm no, calories hauv zaub mov thiab dej haus tau ua ke nrog oxygen los tsim lub zog uas lub cev xav tau ua haujlwm. Yog li ntawd, cov metabolism yog txhais raws li tus naj npawb ntawm cov tshuaj lom neeg muaj sia nyob uas tshwm sim hauv cov cell nyob. Nicotinamide adenine dinucleotide thiab nicotinamide riboside yog ob lub tebchaw uas tseem ceeb heev rau cov metabolism.
Nicotinamide Adenine Dinucleotide yog dab tsi?
Nicotinamide adenine dinucleotide (NAD) yog coenzyme hauv nruab nrab rau cov metabolism uas pom muaj nyob hauv txhua lub hlwb. Cov coenzyme no tau tshawb pom los ntawm British biochemists Arthur Harden thiab William John Young hauv xyoo 1906. Qhov hnyav ntawm qhov sib xyaw no yog 663.43g / mol. Nws yog ib tug dinucleotide uas muaj ob nucleotides koom los ntawm ib pawg phosphate. Ib qho nucleotide muaj adenine nucleobase. Lwm tus muaj nicotinamide. Nws feem ntau muaj nyob rau hauv ob hom: oxidized (NAD+) thiab txo (NADH) cov ntaub ntawv. Hauv cov metabolism, nicotinamide adenine dinucleotide koom nrog hauv cov tshuaj tiv thaiv redox. Nws nqa electrons los ntawm ib qho tshuaj tiv thaiv mus rau lwm qhov. Cov kev hloov pauv hluav taws xob no yog lub luag haujlwm tseem ceeb ntawm nicotinamide adenine dinucleotide.
Daim duab 01: Nicotinamide Adenine Dinucleotide
Nws tseem koom nrog lwm cov txheej txheem ntawm tes xws li kho DNA puas, hloov pauv hloov pauv tom qab (substrate ntawm enzymes), tiv thaiv cov cell tiv thaiv kab mob, teeb tsa lub circadian atherosclerosis, thiab lwm yam hauv cov kab mob, NAD tuaj yeem tsim los ntawm cov amino yooj yim. acids xws li tryptophan los yog aspartic acids (denovo txoj kev). Xwb, nws tuaj yeem raug tsim los ntawm cov khoom noj khoom haus xws li niacin (txoj kev cawm seej). Ntxiv mus, qee qhov NAD hloov mus rau lwm qhov tseem ceeb coenzyme hu ua nicotinamide adenine dinucleotide phosphate (NADP). Cov enzymes uas tsim thiab siv NAD + thiab NADH yog qhov tseem ceeb hauv kev tshuaj. NAD+yog lub hom phiaj ncaj qha thaum kho cov kab mob xws li mob qog noj ntshav, Alzheimer's, Parkinson's disease, tuberculosis, thiab lwm yam.
Nicotinamide Riboside yog dab tsi?
Nicotinamide riboside (niagen) yog lwm hom vitamin B3. Nws ua haujlwm ua tus thawj coj rau nicotinamide adenine dinucleotide. Nicotinamide riboside yog pyridine nucleoside zoo ib yam li vitamin B3. Qhov hnyav molecular ntawm cov tshuaj no yog 255.25 g / mol.
Daim duab 02: Nicotinamide Riboside – NMN vs NR
Nicotinamide riboside tau tshawb pom hauv xyoo 1944 los ntawm Asmeskas cov kws tshawb fawb Wendell Gingrich thiab Fritz Schlenk ua qhov loj hlob rau Haemophilus influenza. Nws yog thawj zaug hu ua yam V. Cov kab mob no nyob thiab nyob ntawm cov ntshav. Thaum tus yam ntxwv V huv huv los ntawm ib tug neeg tau kis tus kab mob Haemophilus influenza, nws muaj nyob rau hauv peb hom: NAD +, NMN, thiab Nicotinamide riboside (NR). NR yog qhov sib xyaw ua ke uas ua rau muaj kev loj hlob sai tshaj plaws ntawm cov kab mob no. Niagen (NR) yooj yim lub hom phiaj kom thim rov qab cov cim ntawm kev laus hauv lub cev los ntawm kev hloov tau yooj yim rau NAD+ Yog li, ChromaDex tuam txhab tau ntawv tso cai patents hauv 2012 los tsim cov txheej txheem coj NR mus rau kev ua lag luam. Tab sis lub tuam txhab ChromaDex tau muaj kev tsis sib haum xeeb nrog Elysium He alth txog txoj cai los tsim cov tshuaj nicotinamide riboside.
Dab tsi zoo sib xws ntawm Nicotinamide Adenine Dinucleotide thiab Nicotinamide Riboside?
- Cov tshuaj no muaj nicotinamide.
- Ob leeg tseem ceeb heev rau cov metabolism.
- Lawv yuav tsum khaws cia hauv qhov txias kom tsis txhob degradation.
- Ob leeg tseem ceeb heev los tiv thaiv tib neeg cov kab mob.
Qhov txawv ntawm Nicotinamide Adenine Dinucleotide thiab Nicotinamide Riboside yog dab tsi?
Nicotinamide adenine dinucleotide yog coenzyme hauv nruab nrab rau cov metabolism uas pom muaj nyob hauv txhua lub hlwb. Ntawm qhov tod tes, nicotinamide riboside yog lwm hom vitamin B3 uas ua haujlwm ua ntej rau nicotinamide adenine dinucleotide. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm nicotinamide adenine dinucleotide thiab nicotinamide riboside. Ntxiv mus, nicotinamide adenine dinucleotide yog qhov sib xyaw loj dua, thaum nicotinamide riboside yog ib qho me me.
Cov hauv qab no infographic tabulates qhov sib txawv ntawm nicotinamide adenine dinucleotide thiab nicotinamide riboside rau ib sab sib piv.
Summary – Nicotinamide Adenine Dinucleotide vs Nicotinamide Riboside
Metabolism tau piav qhia tias yog tag nrho cov tshuaj lom neeg tseem ceeb koom nrog hauv kev tswj hwm lub xeev ntawm cov hlwb hauv cov kab mob. Nicotinamide adenine dinucleotide thiab nicotinamide riboside yog ob lub tebchaw uas tseem ceeb heev rau cov metabolism. Nicotinamide adenine dinucleotide yog coenzyme hauv nruab nrab rau cov metabolism. Ntawm qhov tod tes, nicotinamide riboside yog qhov ua ntej rau nicotinamide adenine dinucleotide. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm nicotinamide adenine dinucleotide thiab nicotinamide riboside.
