Qhov sib txawv tseem ceeb ntawm keratolimbal allograft thiab autologous graft yog keratolimbal allograft siv cadaveric limbal qia hlwb thaum autologous graft siv limbal qia hlwb los ntawm lub qhov muag noj qab haus huv ntawm tus neeg raug phais.
Pob ntseg limbus tsim ciam teb ntawm pob tshab pob tshab thiab opaque sclera. Limbus yog tsim los ntawm pob txha pob txha epithelial qia hlwb, uas yog qhov kawg ntawm pob tshab pob txha epithelium. Yog li ntawd, limbal epithelial qia hlwb tswj kev noj qab haus huv corneal epithelium.
Limbal Stem Cell Deficiency yog dab tsi?
Limbal qia cell deficiency yog kab mob tshwm sim vim kev puas tsuaj ntawm limbal epithelial qia hlwb. Nws tuaj yeem tshwm sim los ntawm kev raug mob los yog kev puas tsuaj ntawm txoj kev loj hlob. Limbal qia cell deficiency yog lub luag haujlwm rau qhov tsis pom kev, qhov mob thiab ua rau lub neej tsis zoo. Limbal qia cell transplantation yog kev kho mob tseem ceeb rau limbal qia cell deficiency. Muaj ntau cov txheej txheem limbal qia cell transplantation. Keratolimbal allograft thiab autologous graft yog ob txoj kev yog ob ntawm lawv.
YKeratolimbal Allograft yog dab tsi?
Keratolimbal allograft yog cov txheej txheem uas siv cadaveric limbal qia hlwb los kho tus neeg mob uas tsis muaj peev xwm qia cell. Qhov kev phais no yog ua tiav thaum tsis muaj lossis txaus siab rau cov txheeb ze pub rau limbal qia hlwb rau kev hloov cov qia cell. Yog li, qhov txheej txheem no siv cov ntaub so ntswg allogenic rau kev hloov pauv. Keratolimbal allograft yog ib qho kev phais mob rau ob sab lossis tag nrho cov qia cell tsis muaj peev xwm. Nws cov lus tshaj tawm txog kev vam meej yog nyob ib puag ncig 73%.
Daim duab 01: Limbal Stem Cell Deficiency
Tom qab keratolimbal allograft, xav tau kev tswj xyuas tom qab tus neeg mob vim nws muaj kev pheej hmoo siab dua ntawm kev tsis lees paub. Qhov no yog vim hais tias cheeb tsam limbal yog heev vascularized, thiab yog yooj yim dua rau lub cev tiv thaiv kab mob. Tau txais cov ntaub so ntswg tsim nyog yog qhov tseem ceeb rau kev ua tiav ntawm cov txheej txheem. Txawm li cas los xij, ntxiv nrog rau kev tsis lees paub txog kev tiv thaiv kab mob, tuaj yeem muaj teeb meem cuam tshuam txog kev cuam tshuam thiab kev cuam tshuam ntawm lub ntsej muag ntev.
Autologous Graft yog dab tsi?
Autologous graft yog lwm txoj kev hloov ntawm qia cell. Autologous limbal qia cell transplantation tshwj xeeb tshaj yog siv limbal qia hlwb los ntawm tus neeg mob lub qhov muag noj qab haus huv. Yog li ntawd, nws yog ib qho tsim nyog yuav tau sau cov qia hlwb los ntawm tus neeg mob nws tus kheej. Tom qab sau qoob, cov cell yog cultured thiab transplanted. Yog li ntawd, nws yog ib hom autologous ex-vivo cultivated limbal epithelial transplantation.
Vim tias autologous graft siv ib tus neeg tus kheej libal qia hlwb, cov txheej txheem no qhia tau hais tias epithelialization sai dua thiab mob tsawg dua. Lwm qhov zoo dua yog tias nws xav tau cov ntaub so ntswg tsawg dua piv rau kev hloov pauv allogeneic. Ntxiv mus, qhov kev vam meej ntawm autologous graft yog siab dua li ntawm allogeneic graft. Autologous graft yog tsim nyog rau unilateral limbal qia cell deficiency.
Dab tsi yog qhov zoo sib xws ntawm Keratolimbal Allograft thiab Autologous Graft?
- Keratolimbal allograft thiab autologous graft yog ob txoj hauv kev ntawm limbal qia cell transplantation.
- Ob txoj kev tuaj yeem rov qab kho qhov muag tsis pom kev.
Qhov txawv ntawm Keratolimbal Allograft thiab Autologous Graft yog dab tsi?
Keratolimbal allograft yog cov txheej txheem limbal stem cell transplantation uas siv cadaveric limbal qia hlwb rau kev tsim kho ntawm lub qhov muag thaum lub autologous graft yog qia cell transplantation txheej txheem uas siv limbal qia hlwb los ntawm lub qhov muag noj qab haus huv ntawm ib tug neeg. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm keratolimbal allograft thiab autologous graft. Immunogenic tsis kam yog tsawg hauv autologous graft dua li hauv keratolimbal allograft. Lwm qhov sib txawv ntawm keratolimbal allograft thiab autologous graft yog qhov ua tiav ntawm autologous graft yog siab dua hauv keratolimbal allograft.
Cov hauv qab no qhia txog qhov sib txawv ntawm keratolimbal allograft thiab autologous graft.
Summary – Keratolimbal Allograft vs Autologous Graft
Keratolimbal allograft thiab autologous graft yog ob txoj kev phais ntawm limbal qia cell transplantation. Keratolimbal allograft siv cadaveric limbal qia hlwb los yog cov ntaub so ntswg allogenic los ntawm tus pub thaum autologous graft siv tus neeg tus kheej limbal qia hlwb. Qhov no yog qhov sib txawv tseem ceeb ntawm keratolimbal allograft thiab autologous graft. Autologous graft yog ua rau unilateral limbal qia cell deficiency thaum keratolimbal allograft yog ua rau ob sab lossis tag nrho limbal qia cell deficiency. Qhov kev vam meej ntawm autologous graft yog siab dua nyob rau hauv kev sib piv rau keratolimbal allograft.
