Qhov sib txawv tseem ceeb ntawm ionotropic thiab metabotropic receptors yog tias ionotropic receptors tso cai rau kev khi ntawm ionic ligands rau lawv uas qhib rau ion channel. Lub caij no, metabotropic receptors tso cai rau kev khi ntawm cov tshuaj ligands rau cov receptors, pib ua ib qho kev cuam tshuam ntawm kev sib txuas nrog G protein.
Kev xa tawm thiab xa cov membrane yog cov txheej txheem tseem ceeb hauv biology. Ob leeg ua lub luag haujlwm tseem ceeb hauv kev tswj cov metabolism hauv lub cev. Feem ntau ntawm txoj kev metabolic thiab kev thauj mus los ntawm daim nyias nyias yog los ntawm cov receptors uas khi nrog ligands, uas tuaj yeem yog ionic ligands lossis tshuaj ligands.
Ionotropic Receptors yog dab tsi?
Ionotropic receptors, tseem hu ua ion channels, yog cov channel proteins uas pab txhawb kev thauj cov ions. Channel proteins qhib thaum ions khi rau cov receptors. Hauv lwm lo lus, kev khi ntawm ions rau cov receptors ua rau qhib cov ion channel.
Daim duab 01: Ionotropic Receptors
Ion channels tsis nyob hauv lub xeev kaw lossis qhib txhua lub sijhawm. Tab sis, lawv feem ntau nyob hauv lub xeev kaw. Kev khi ntawm cov ions mus rau ionotropic receptors tsis ua rau kev ua kom muaj cov khoom siv thib ob. Yog li ntawd, cov nyhuv ntawm ionotropic receptor tsis kav ntev. Cov tshuaj tiv thaiv thaum ua kom cov ionotropic receptors tsis ua rau lub cascading transduction mechanism. Tsis tas li ntawd, ionotropic receptors ua lub luag haujlwm tseem ceeb hauv kev xa cov paj hlwb. Tsis tas li ntawd, cov no yog cov ntsiab lus tseem ceeb hauv cov txheej txheem thauj khoom xws li sodium-hydrogen transporter thiab potassium transporter.
Dab tsi yog Metabotropic Receptors?
Metabotropic receptor yog ib hom receptor koom nrog hauv cov teeb liab hloov pauv ntawm cov tub txib thib ob khi cov receptor. Cov metabotropic receptor yog pom nyob rau saum npoo ntawm cov hlwb. Feem ntau hom receptor rau cov metabotropic receptor yog G protein-coupled receptors. Yog li, metabotropic receptors muaj cov receptors zoo li glutamate receptors, muscarinic acetylcholine receptors thiab serotonin receptors. Feem ntau cov metabotropic receptors yog neurotransmitter ligands.
Daim duab 02: Metabotropic Receptors
Lub tshuab ntawm kev ua ntawm metabotropic receptors nyob ntawm ligand binding. Raws li kev khi ntawm G protein-coupled receptor rau ib lub ligand, ib qho kev cuam tshuam ntawm kev tshwm sim yog pib los ntawm kev ua kom muaj ntau yam molecules thib ob. Qhov qhib ntawm metabotropic receptors yuav siv sij hawm ntev dua vim nws cuam tshuam rau kev ua kom muaj ntau lub molecules. Li no, kev ruaj ntseg ntawm cov nyhuv ntawm metabotropic receptors kuj siab thiab ntau dua.
Muaj ntau yam haujlwm hauv metabotropic receptors. Lawv tuaj yeem qhib lossis kaw ib qho channel lossis koom nrog hauv kev sib txuas lus paj hlwb tshwj xeeb.
Dab tsi yog qhov zoo sib xws ntawm Ionotropic thiab Metabotropic Receptors?
- Ionotropic thiab metabotropic receptors yog ob hom membrane receptors.
- Ob leeg yog qhov tseem ceeb hauv kev sib txuas lus neurotransmission.
- Cov receptors khi rau lawv cov ligands tshwj xeeb
- Vim li no, lawv qhov tshwj xeeb thiab rhiab heev thaum lub sij hawm khi nrog cov ligands.
Qhov txawv ntawm Ionotropic thiab Metabotropic Receptors yog dab tsi?
Qhov sib txawv tseem ceeb ntawm ionotropic thiab metabotropic receptors yog hom ligand uas khi rau txhua tus receptor. Ionic ligands khi rau ionotropic receptors thaum uas tsis yog-ionic ligands khi rau metabotropic receptors. Thaum khi, metabotropic receptors pib ua cov tshuaj tiv thaiv cascading lossis lub teeb liab hloov pauv. Tab sis, ionotropic receptors yuav qhib ib qho ion gated channel. Yog li, qhov no yog lwm qhov sib txawv ntawm ionotropic thiab metabotropic receptors. Vim yog cov teebmeem no, kev ruaj khov thiab kev tiv thaiv ntawm cov nyhuv kuj txawv ntawm cov ionotropic thiab metabotropic receptors.
Cov hauv qab no infographic qhia txog qhov sib txawv ntawm ionotropic thiab metabotropic receptors.
Summary – Ionotropic vs Metabotropic Receptors
Ionotropic thiab metabotropic receptors yog ob hom receptors uas ua haujlwm hauv kev thauj mus los ntawm cov membrane thiab cov teeb liab hloov. Ionotropic receptors khi rau ionic ligands xws li K+, Na+, Cl–, thiab Ca 2+ Metabotropic receptors khi nrog cov tsis-ionic ligands xws li tshuaj receptors lossis G protein-coupled receptors. Thaum khi, cov receptors pib muaj cov tshuaj tiv thaiv cascading xws li cov teeb liab hloov pauv. Ob qho tib si ntawm cov txheej txheem no ua lub luag haujlwm tseem ceeb hauv neurotransmission. Txawm li cas los xij, ionotropic receptors ua haujlwm raws li cov channel qhib thiab kaw thaum metabotropic receptors tsis yog cov channel. Yog li, qhov no qhia txog qhov sib txawv ntawm ionotropic thiab metabotropic receptors.
