Qhov sib txawv tseem ceeb ntawm cov receptors sab hauv thiab cov cell nto receptors yog cov receptors sab hauv muaj nyob rau hauv cytoplasm thiab teb rau hydrophobic ligands uas nkag mus rau hauv lub cell hla lub plasma membrane thaum lub cell nto receptors nyob rau hauv cell membrane thiab teb rau. sab nraud ligands uas tsis mus hla lub cell membrane.
Cell signaling yog txheej txheem tseem ceeb hauv ntau cov kab mob. Cells tso tawm cov cim qhia txog lub npe hu ua ligands. Lawv yog cov me me, volatile los yog soluble molecules uas tuaj yeem khi nrog receptors. Receptors mediate lub teeb liab transduction rau cellular teb. Receptors yog cov proteins uas feem ntau nyob ntawm qhov chaw lossis hauv cytoplasm. Ib lub ligand khi tsuas yog nrog ib qho receptor tshwj xeeb. Receptors tuaj yeem yog cell nto receptors lossis cov receptors sab hauv (intracellular receptors).
Dab tsi yog Internal Receptors?
Internal receptors lossis intracellular receptors yog cov receptor proteins pom hauv lub cell hauv cytoplasm. Cov receptors no teb rau cov ligands uas nkag mus rau hauv lub cell los ntawm lub cell membrane. Thaum lub ligand khi nrog cov receptor intracellular, nws hloov pauv hloov pauv. Gene qhia yog ib qho ntawm cov txheej txheem tseem ceeb tshaj plaws uas tshwm sim hauv ib lub cell. Intracellular receptor-ligand complexes taug kev mus rau nucleus thiab xa cov cim tsim nyog rau cov noob qhia thiab nws cov kev cai. Yog li, cov receptors sab hauv tuaj yeem cuam tshuam ncaj qha rau cov noob qhia hauv cov hlwb yam tsis muaj kev koom tes ntawm cov tub txib thib ob.
Daim duab 01: Intracellular Receptors
Ntxiv rau cov saum toj no, cov tshuaj hormones ntawm tes siv cov receptors intracellular. Tsis tas li ntawd, nuclear receptors kuj muaj nyob rau hauv lub cell nucleus. Sib nrug ntawm lawv, endoplasmic reticulum kuj tseem siv cov receptors intracellular.
Cell Surface Receptors yog dab tsi?
Cell nto receptors yog transmembrane proteins anchored nrog cell membrane. Cov receptors khi rau sab nraud ligands uas tsis hla lub cell membrane thiab nkag mus rau hauv lub cell. Tshwj xeeb tshaj yog, cov receptors no hloov cov teeb liab extracellular rau hauv cov teeb liab intracellular. Qhov tseem ceeb tshaj plaws, cell deg receptors yog tshwj xeeb rau ib hom cell.
Daim duab 02: Cell Surface Receptors
Muaj peb hom cell nto receptors li ion channel-txuas receptors, G-protein-linked receptors, thiab enzyme-txuas receptors. Cov receptors no ua rau feem ntau ntawm cov xov tooj ntawm tes taw qhia hauv ntau lub cev.
Dab tsi zoo sib xws ntawm Internal Receptors thiab Cell Surface Receptors?
- Internal receptors thiab cell nto receptors yog ob lub ntsiab ntawm cell receptors.
- Ob leeg muaj peev xwm khi nrog cov cim taw qhia lossis ligands.
- Lawv koom nrog cov teeb liab hloov.
- Qhov tseeb, ob qho tib si sab hauv receptors thiab cell nto receptors koom nrog feem ntau txoj kev taw qhia.
- Ntxiv mus, lawv yog cov proteins.
Qhov txawv ntawm Internal Receptors thiab Cell Surface Receptors yog dab tsi?
Internal receptors yog cov receptors tam sim no hauv cytoplasm. Nyob rau hauv sib piv, cell nto receptors yog cov receptors tam sim no ntawm lub cell membrane. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm cov receptors sab hauv thiab cov cell nto receptors. Ntxiv mus, qhov sib txawv ntxiv ntawm cov receptors sab hauv thiab cov cell nto receptors yog tias cov receptors sab hauv khi nrog cov ligands uas nkag mus rau hauv lub cell thaum lub cell nto receptors khi nrog cov ligands sab nraud.
Cov hauv qab no infographic qhia txog qhov sib txawv ntawm cov receptors sab hauv thiab cov cell nto receptors.
Summary – Internal Receptors vs Cell Surface Receptors
Internal receptors thiab intracellular receptors yog ob lub ntsiab ntawm cov receptors uas kho cov teeb liab hloov hauv cov hlwb. Internal receptors nyob rau hauv lub cytoplasm thiab khi nrog cov hydrophobic ligands uas nkag mus rau hauv lub cell hla lub cell membrane. Nyob rau hauv sib piv, cell nto receptors muaj nyob rau ntawm lub cell membrane, thiab lawv khi nrog rau sab nraud ligands uas yog sab nraum lub cell membrane. Yog li, qhov no yog cov ntsiab lus ntawm qhov sib txawv ntawm cov receptors sab hauv thiab cov cell nto receptors.
