Qhov Tseem Ceeb Qhov txawv - Interferon Beta-1A vs 1B
Nyob rau hauv cov ntsiab lus ntawm cov tshuaj niaj hnub no, ntau hom tshuaj tau tsim los siv cov thev naus laus zis sib txawv txhawm rau txhim kho kev kho mob zoo tiv thaiv kab mob sib txawv. Hauv kev kho mob ntau yam sclerosis uas yog tus kab mob demyelinating, Interferon Beta-1A thiab Interferon Beta-1B tau siv dav. Ob qho kev kho mob tsis yog kev kho mob rau tus kab mob es tsis txhob lawv txo qhov kev mob ntawm tus kab mob. Interferon Beta-1A yog siv thaum lub sijhawm ntxov ntawm tus kab mob kom tau txais txiaj ntsig zoo, thiab Interferon Beta-1B yog siv thaum lub sijhawm thib ob ntawm tus kab mob. Qhov no yog qhov sib txawv tseem ceeb ntawm Interferon Beta-1A thiab Interferon Beta-1B.
Interferon Beta-1A yog dab tsi?
Hauv kev kho mob ntau yam sclerosis, Interferon Beta 1A yog siv. Multiple sclerosis yog ib yam kab mob uas tshwm sim hauv lub paj hlwb. Cov paj hlwb raug insulated los ntawm ib lub npog hu ua Myelin sheath. Lub myelin sheath yog tsim los ntawm Schwann hlwb uas ua rau kom ceev ntawm kev sib kis ntawm paj hlwb impulses. Ntau tus sclerosis yog ib yam kab mob demyelinating uas cuam tshuam cov ntaub so ntswg myelin. Ntau tus kab mob sclerosis ua rau lub cev thiab lub hlwb sib txawv.
Interferon Beta 1A yog ib yam tshuaj uas nyob hauv tsev neeg ntawm interferons. Nws yog ib qho cytokine thiab yog tsim los ntawm mammalian hlwb. Interferon Beta 1A tsis yog ib yam tshuaj uas yuav kho ntau yam kab mob sclerosis. Cov tshuaj yuav ua tau zoo nyob rau hauv thiaj li yuav txo tau qhov kev loj hlob sai ntawm tus kab mob yog hais tias nws yog pom nyob rau hauv thaum ntxov theem. Interferon Beta 1A yog siv rau hauv cov ntawv txhaj tshuaj. Thaum nws tau txhaj tshuaj, thaj tsam ntawm daim tawv nqaij ntawm kev txhaj tshuaj yog qhov cuam tshuam rau kev loj hlob ntawm daim tawv nqaij cov tshuaj tiv thaiv uas suav nrog cutaneous necrosis.
Qhov tshwm sim ntawm cov tawv nqaij tshwm sim ntau dua rau cov poj niam hauv thawj lub hlis ntawm kev kho mob. Yog tias cov tshuaj tiv thaiv ntawm daim tawv nqaij yog mob me, cov tshuaj tau muab txuas ntxiv mus. Tab sis yog hais tias tej yam kev mob xws li cutaneous necrosis tshwm sim, cov txheej txheem kev kho mob yuav tsum txiav. Nrog rau lub sijhawm, vim kev puas tsuaj ntawm cov ntaub so ntswg rog, qhov chaw txhaj tshuaj tuaj yeem raug dented. Qhov no yog qhov tsis tshua muaj tshwm sim thaum kho Interferon Beta 1A. Txhawm rau tiv thaiv qhov tshwm sim ntawm kev kis kab mob ntawm qhov chaw txhaj tshuaj, qhov chaw txhaj tshuaj yog tig rau hauv cov neeg mob thiab siv cov txheej txheem aseptic.
Daim duab 01: Interferon Beta 1A
Cov tshuaj Interferon Beta 1A koom nrog hauv kev sib npaug ntawm cov tshuaj tiv thaiv thiab cov tshuaj tiv thaiv uas muaj nyob hauv lub hlwb. Tsis tas li ntawd, nws ua rau txo cov hlwb inflammatory uas hla cov hlab ntsha-hlwb barrier. Interferon Beta 1A kev kho mob ua rau txo qis kev mob ntawm cov neurons thiab txhim kho cov ciaj sia taus ntawm cov neurons los ntawm kev nce qib ntawm cov paj hlwb loj hlob.
Interferon Beta-1B yog dab tsi?
Interferon Beta-1B yog lwm hom cytokine uas yog tsev neeg, interferons. Qhov no yog synthesized nyob rau hauv hloov kho Escherichia coli. Cov tshuaj no yog siv tau zoo thaum kho mob thib ob ntawm ntau yam sclerosis. Thawj theem ntawm ntau yam sclerosis yog kho nrog Interferon Beta-1A, thiab nws tau pom tias tib cov tshuaj tsis zoo rau theem thib ob ntawm tus kab mob. Yog li, Interferon Beta-1B yog siv los ua kev kho mob rau theem thib ob ntawm ntau yam sclerosis. Cov tshuaj tsis ua raws li kev kho tus kab mob es nws yuav txo tau tus kab mob sai sai.
Tsis zoo li Interferon Beta-1A, cov teebmeem ntawm Interferon Beta-1B tseem tab tom tshawb nrhiav. Cov tshuaj yog siv raws li kev txhaj tshuaj subcutaneous. Cov tshuaj tsuas yog muaj nyob rau hauv daim ntawv ntawm kev txhaj tshuaj. Txij li thaum nws tau muab rau subcutaneous txheej ntawm daim tawv nqaij, qhov chaw ntawm kev txhaj tshuaj yog qhov cuam tshuam rau qhov tshwm sim ntawm cov kab mob. Qhov no tshwm sim nyob rau hauv cov poj niam ntau dua li txiv neej. Qhov tshwm sim ntawm cov kab mob ntawm daim tawv nqaij ncaj qha cuam tshuam rau cov txheej txheem kho. Yog hais tias tus kab mob yog mob me me, cov tshuaj yog siv tas li. Tab sis yog hais tias tej yam kev mob xws li cutaneous necrosis tshwm sim, kev muab tshuaj yog txiav. Qhov tshwm sim ntawm kev kis kab mob tuaj yeem txo qis nrog kev xyaum ua aseptic.
Zoo ib yam li Interferon Beta-1A, Interferon Beta-1B koom nrog hauv kev sib npaug ntawm cov tshuaj tiv thaiv kab mob thiab cov tshuaj tiv thaiv uas muaj nyob hauv lub hlwb. Kev kho mob cuam tshuam txog kev txo qis ntawm neuron o thiab tiv thaiv kev hloov pauv ntawm cov kab mob inflammatory hla cov ntshav-hlwb teeb meem. Kev muaj sia nyob neuronal yog txhawb nqa los ntawm Interferon Beta-1B los ntawm kev tsim cov paj hlwb.
Dab tsi yog qhov zoo sib xws ntawm Interferon Beta-1A thiab 1B?
- Interferon Beta-1A thiab 1B qhia tib yam kev mob tshwm sim xws li kab mob ntawm daim tawv nqaij uas tuaj yeem ua rau cov nqaij hlav necrosis.
- Txhua yam tshuaj tsis ua raws li kev kho tab sis txo qis kev kis tus kabmob mus rau qee qhov.
- Ob cov tshuaj sib npaug ntawm cov tshuaj tiv thaiv kab mob thiab cov tshuaj tiv thaiv kab mob hauv lub hlwb.
- Ob cov tshuaj tiv thaiv kev hloov pauv ntau dhau ntawm cov hlwb inflammatory hla cov ntshav-hlwb
- Ob cov tshuaj nce tus nqi ntawm cov neeg muaj sia nyob los ntawm kev tsim cov paj hlwb.
Qhov txawv ntawm Interferon Beta-1A thiab 1B yog dab tsi?
Interferon Beta-1A vs Interferon Beta-1B |
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| Interferon Beta - 1A yog ib yam tshuaj uas siv thaum lub sijhawm pib ntawm tus kab mob kom tau txais txiaj ntsig zoo. | Interferon Beta – 1B yog lwm hom cytokine uas yog tsev neeg, interferons. |
| Cov xwm txheej zoo | |
| Interferon Beta - 1A yog siv los ua cov tshuaj kho tau zoo thaum lub sijhawm thawj theem ntawm ntau yam sclerosis. | Interferon Beta - 1B yog siv tau zoo rau kev kho mob thib ob ntawm tus kab mob. |
| Synthesis | |
| Nyob rau hauv mammalian cells. | In hloov kho Escherichia coli. |
Summary – Interferon Beta-1A vs 1B
Interferon Beta-1A thiab Interferon Beta-1B yog ob hom kev kho mob uas siv thaum kho ntau yam. Ob qho tshuaj tsis ua raws li kev kho mob rau tus kab mob tab sis txo qis kev loj hlob ntawm tus kab mob. Interferon Beta-1A yog muab rau thaum pib ntawm tus kab mob thaum lub sij hawm Interferon Beta-1B yog muab nyob rau hauv lub thib ob theem. Ob qho kev kho mob muaj cov kev mob tshwm sim zoo sib xws uas yog kab mob ntawm daim tawv nqaij. Cov kab mob tuaj yeem ua rau tuag taus xws li cutaneous necrosis. Ob qho tshuaj tiv thaiv kev hloov pauv ntau dhau ntawm cov kab mob inflammatory thoob plaws hauv cov ntshav-hlwb teeb meem thiab nce tus nqi ntawm neuronal ciaj sia los ntawm kev tsim cov paj hlwb. Qhov no tuaj yeem txheeb xyuas qhov txawv ntawm Interferon Beta-1A thiab Interferon Beta-1B.
Download PDF Version ntawm Interferon Beta-1A vs 1B
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li daim ntawv ceeb toom. Thov download PDF version ntawm no Qhov txawv Ntawm Interferon Beta-1A thiab 1B
