Qhov sib txawv tseem ceeb ntawm fibroblast thiab fibrocyte yog tias fibroblast yog ib lub xovtooj ntawm tes koom nrog hauv kev tso tawm ntawm cov cellular matrix, collagen thiab lwm cov cellular molecules ntawm cov ntaub so ntswg sib txuas thaum fibrocyte yog ib daim ntawv tsis muaj zog ntawm me me fibroblast.
Fibroblast thiab fibrocyte yog ob lub xeev sib txawv ntawm tib lub xov tooj ntawm tes, feem ntau cuam tshuam nrog kev tsim tawm ntau hom extracellular matrix Cheebtsam hauv cov ntaub so ntswg sib txuas. Txawm li cas los xij, muaj qhov sib txawv ntawm fibroblast thiab fibrocyte raws li lawv qhov kev ua haujlwm thiab lub luag haujlwm ua haujlwm hauv cov kab mob lom.
YFibroblast yog dab tsi?
Fibroblasts yog cov kab mob tsis zoo-zoo li lub tiaj tus nrog cov txheej txheem feeb protruding tawm ntawm lub cev ntawm tes. Cov hlwb no muaj ellipsoidal, flattened, loj nucleus nrog finely faib chromatin thiab kuj muaj 1-2 nucleoli. Thaum fibroblasts ua haujlwm, cellular organelles zoo li Golgi apparatus thiab ntxhib endoplasmic reticulum ua qhov tseem ceeb. Fibroblasts los ntawm mesenchymal qia hlwb los yog los ntawm fibrocytes (daim ntawv tsis muaj zog ntawm fibroblasts).
Daim duab 01: Fibroblast
Lub luag haujlwm tseem ceeb ntawm fibroblasts yog tsim ntau yam khoom siv ntxiv nrog rau cov proteoglycans, collagens, proteolytic enzymes, kev loj hlob, thiab qee qhov taw qhia molecules zoo li cytokines. Hauv tib neeg lub siab, cov hlwb no pab hauv kev sib cuam tshuam ntawm tes nrog lwm cov fibroblasts, myocytes thiab endothelial hlwb. Tsis tas li ntawd, cov hlwb no ua rau muaj tshuaj lom neeg, khoom siv hluav taws xob thiab hluav taws xob hauv lub plawv.
YFibrocyte yog dab tsi?
Fibrocytes hlwb, tseem hu ua pob txha pob txha-derived mesenchymal progenitor hlwb, yeej ua raws li cov hlwb precursor ntawm fibroblasts. Qhov kev txaus siab ntawm fibrocytes tau nce sai heev nyob rau hauv kaum xyoo dhau los vim lawv lub luag haujlwm tseem ceeb hauv cov kab mob lom. Cov hlwb no feem ntau ua rau kho qhov txhab thiab fibrosis vim lawv lub peev xwm ntawm kev sib txawv rau hauv lawv daim ntawv nquag -fibroblasts.
Daim duab 02: Connective Tissue
Tsis tas li ntawd, fibrocytes tseem ua lub luag haujlwm hauv qee yam kev tiv thaiv kab mob nrog rau kev tso tawm ntawm collagen fibers. Piv nrog rau active fibroblasts, fibrocytes yog cov hlwb me. Lawv muaj ib tug me me elongated nucleus thiab ib tug me me ntawm rER thiab Golgi lub cev. Tsis tas li ntawd, cov hlwb no yog spindle-puab.
Dab tsi zoo sib xws ntawm Fibroblast thiab Fibrocyte?
- Fibrocyte yog ib daim ntawv tsis muaj zog ntawm fibroblast.
- Fibroblast thiab fibrocytes muaj nyob rau hauv cov ntaub so ntswg sib txuas.
- Ntxiv mus, lawv koom nrog kev kho cov ntaub so ntswg thiab kho qhov txhab.
Qhov txawv ntawm Fibroblast thiab Fibrocyte yog dab tsi?
Fibroblast yog ib lub xovtooj ntawm tes uas zais cov cellular matrix, collagen thiab lwm cov macromolecules extracellular ntawm cov ntaub so ntswg sib txuas. Fibrocyte yog ib tug precursor cell ntawm fibroblast. Qhov no yog qhov sib txawv tseem ceeb ntawm fibroblast thiab fibrocyte. Fibroblast yog lub cell loj thaum fibrocyte yog ib lub cell me. Tsis tas li ntawd, lwm qhov sib txawv ntawm fibroblast thiab fibrocyte yog tias fibroblasts feem ntau tsim cov khoom siv ntxiv xws li proteoglycans, collagens, proteolytic enzymes, kev loj hlob thiab qee cov cim qhia txog molecules zoo li cytokines, thaum fibrocytes pab hauv qee yam kev tiv thaiv kab mob, tso tawm ntawm collagen, thiab kho qhov txhab.
Summary – Fibroblast vs Fibrocyte
Fibroblast thiab fibrocyte yog ob hom hlwb uas muaj nyob rau hauv cov ntaub so ntswg sib txuas. Hauv kev hais txog qhov sib txawv ntawm fibroblast thiab fibrocyte, fibroblasts yog cov hlwb uas nquag nquag siv thaum fibrocytes yog cov hlwb tsis ua haujlwm. Qhov tseeb, fibrocytes yog ib daim ntawv tsis muaj zog ntawm fibroblasts. Fibroblasts loj dua fibrocytes. Ntxiv mus, lawv muaj lub ovoid nucleus loj thaum fibrocyte muaj ib tug me me elongated nucleus.
