Qhov txawv ntawm embryonic thiab somatic qia hlwb yog tias embryonic qia hlwb yog pluripotent undifferentiated hlwb uas muaj embryonic keeb kwm thaum somatic qia hlwb yog multipotent undifferentiated hlwb uas yog cov ntaub so ntswg thiab lub hauv paus chiv keeb.
qia hlwb yog cov hlwb uas tsis muaj qhov sib txawv uas muaj peev xwm loj hlob mus rau hauv cov ntaub so ntswg los yog lub cev. Feem ntau, muaj ob hom kab mob loj xws li embryonic qia hlwb thiab cov neeg laus qia hlwb (somatic qia hlwb). Nyob rau hauv rooj plaub ntawm kev sib txawv, embryonic qia hlwb tuaj yeem sib txawv rau txhua hom hlwb. Nyob rau hauv sib piv, somatic qia hlwb tsuas yog sib txawv rau hauv ob peb cov ntaub so ntswg tshwj xeeb. Yog li ntawd, embryonic qia hlwb yog pluripotent thaum somatic qia hlwb yog multipotent. Hauv cov lus yooj yim, lub peev xwm ntawm kev sib txawv yog siab nyob rau hauv embryonic qia hlwb nyob rau hauv kev sib piv rau cov somatic qia hlwb.
Dab tsi yog embryonic Stem Cells?
Cov qia hlwb yog ib hom ntawm cov hlwb uas tsis muaj qhov sib txawv tam sim no nyob rau theem pib ntawm kev loj hlob ntawm embryonic. Lub cell loj ntawm lub blastocyst yog tsim los ntawm embryonic qia hlwb. Cov embryonic qia hlwb no pluripotent nyob rau hauv qhov. Yog li, lawv tuaj yeem sib txawv rau txhua hom cell. Kev rho tawm ntawm embryonic qia hlwb tuaj yeem ua tiav los ntawm blastocyst theem ntawm kev loj hlob embryonic rau qia cell kab lis kev cai. Tom qab kev tshem tawm, cov hlwb raug kev loj hlob thiab kev faib tawm nyob rau hauv vitro mob. Lub embryonic qia hlwb muaj peev xwm loj hlob nyob rau hauv tshwj xeeb high nutrient media uas lawv sib txawv rau hauv peb txheej kab mob: ectoderm, endoderm, thiab mesoderm.
Daim duab 01: Cov Kabmob Embryonic
Hauv kev kho niaj hnub no, embryonic qia hlwb yog cov cuab yeej tseem ceeb hauv kev kho dua tshiab thiab hloov cov ntaub so ntswg tom qab raug mob lossis kab mob. Cov kab mob uas siv embryonic qia cell kho tam sim no yog ntshav qab zib, neurodegenerative disorders, qaum qaum, thiab cov leeg nqaij raug mob.
Dab tsi yog Somatic Stem Cells?
Somatic qia hlwb yog cov qia hlwb uas muaj nyob rau hauv cov ntaub so ntswg thiab cov kabmob hauv cov laus. Yog li ntawd, 'cov neeg laus qia hlwb' yog ib lub ntsiab lus ntawm somatic qia hlwb. Yog li, cov neeg laus qia hlwb pib los ntawm cov ntaub so ntswg thiab cov kabmob uas paub tab. Lawv yog cov cell multipotent; Qhov no txhais tau tias lawv tuaj yeem sib txawv rau ntau hom hlwb, tab sis tsis pluripotent zoo li embryonic qia hlwb. Muaj ntau hom somatic qia hlwb xws li hematopoietic qia hlwb, plab hnyuv qia hlwb, endothelial qia hlwb, neuronal qia hlwb, thiab mesenchymal qia hlwb.
Daim duab 02: Somatic Stem Cells
Thaum kev faib, somatic qia hlwb raug ob txoj hauv kev. Lawv yog symmetric division thiab asymmetric division. Lub symmetric division tsim cov ntxhais hlwb ntawm cov khoom zoo sib xws whereas asymmetric division tsim ib tug ntxhais zoo sib xws cell thiab ib tug txawv progenitor cell.
Muaj ntau qhov kev siv ntawm somatic qia hlwb hauv kev tshawb fawb. Lawv muaj txiaj ntsig zoo hauv ntau cov txheej txheem kuaj tshuaj los kuaj xyuas cov teebmeem ntawm cov tshuaj tshwj xeeb lossis cov metabolites. Ntxiv mus, somatic qia hlwb muaj txiaj ntsig los txiav txim siab tus cwj pwm ntawm tes ntawm cov kab mob tshwj xeeb thiab lawv txoj hauv kev taw qhia. Tsis tas li ntawd, cov kws tshawb fawb siv cov hlwb somatic raws li kev kho mob vim lawv muaj peev xwm rov tsim cov hlwb thaum muaj xwm txheej zoo.
Dab tsi zoo sib xws ntawm Embryonic thiab Somatic Stem Cells?
- Embryonic thiab somatic qia hlwb yog cov hlwb tsis muaj qhov sib txawv uas muaj lub zog sib txawv rau ntau hom cell.
- Ob leeg yog rov tsim dua.
- Ntxiv mus, lawv tuaj yeem nthuav dav hauv vitro
- Cov hlwb no xav tau cov khoom noj muaj txiaj ntsig zoo rau kev loj hlob zoo.
- tseem ceeb tshaj, cov kws tshawb fawb siv ob hom hlwb hauv kev kho thiab kev tshawb fawb.
Qhov txawv ntawm Embryonic thiab Somatic Stem Cells yog dab tsi?
Qhov sib txawv tseem ceeb ntawm embryonic thiab somatic qia hlwb yog lawv qhov chaw ntawm kev rho tawm. Blastocyst theem ntawm lub embryonic txoj kev loj hlob yog qhov chaw ntawm extraction ntawm embryonic qia hlwb thaum cov ntaub so ntswg tshwj xeeb yog qhov chaw ntawm extraction ntawm somatic qia cell. Tshwj xeeb tshaj yog, embryonic qia hlwb tuaj yeem sib txawv rau txhua hom hlwb. Nyob rau hauv sib piv, somatic qia hlwb tsis tuaj yeem sib txawv rau txhua hom hlwb thiab tsuas tuaj yeem sib txawv rau qee hom hlwb raws li lawv lub hauv paus chiv keeb. Yog li, qhov no kuj yog qhov sib txawv loj ntawm embryonic thiab somatic qia hlwb.
Lwm qhov sib txawv ntawm embryonic thiab somatic qia hlwb yog lawv cov txheej txheem ntawm tes. Cell culturing ntawm somatic qia hlwb muaj zog ntau dua nyob rau hauv kev sib piv rau embryonic qia cell kab lis kev cai.
Cov hauv qab no nthuav tawm cov ntaub ntawv ntxiv txog qhov sib txawv ntawm embryonic thiab somatic qia hlwb.
Summary – Embryonic vs Somatic Stem Cells
Stem cells yog cov hlwb tsis txawv. Muaj ob chav kawm dav ntawm qia hlwb li embryonic qia hlwb thiab somatic qia hlwb. Hauv kev xaus qhov sib txawv ntawm embryonic thiab somatic qia hlwb, embryonic qia hlwb tuaj yeem sib txawv rau txhua hom hlwb; yog li ntawd, lawv yog pluripotent. Nyob rau hauv sib piv, somatic qia hlwb los yog cov laus qia hlwb muaj peev xwm sib txawv tsuas yog rau hauv tej yam hlwb; yog li ntawd, lawv yog multipotent. Qhov tseem ceeb tshaj, qhov sib txawv tseem ceeb ntawm embryonic thiab somatic qia hlwb yog qhov chaw ntawm qhov muab los ntawm cov cell hom. Cov embryonic qia hlwb tau muab los ntawm blastocyst thaum cov kab mob somatic tau muab los ntawm cov kabmob tshwj xeeb raws li qhov yuav tsum tau ua.
