Qhov sib txawv tseem ceeb ntawm biotransformation thiab metabolism yog tias biotransformation yog ib feem ntawm cov metabolism hauv uas cov tshuaj biochemical hloov pauv tshwm sim hauv ib qho tshuaj lossis cov khoom sib xyaw thaum cov metabolism yog hais txog txhua qhov kev cuam tshuam biochemical tshwm sim hauv lub cev muaj sia.
Metabolism yog ib lo lus dav, uas tsis suav nrog tag nrho cov tshuaj biochemical uas tshwm sim hauv cov kab mob uas muaj sia nyob tab sis kuj tseem muaj cov metabolism ntawm cov tshuaj thiab. Yog li ntawd, cov metabolism yog ua haujlwm los ntawm kev nkag mus ntawm ib qho kev sib txuas mus rau egestion ntawm lub compound nyob rau hauv cov kab mob. Ntxiv mus, cov metabolism hauv cov tshuaj los yog xenobiotic yog ib qho tseem ceeb ntawm Biochemistry kawm thoob plaws ntiaj teb. Xenobiotic metabolism suav nrog ntau cov txheej txheem. Lub hom phiaj tseem ceeb ntawm xenobiotic metabolism lossis cov tshuaj metabolism hauv cov tshuaj muaj xws li tag nrho cov kev hloov kho biochemical uas tshwm sim hauv cov tshuaj. Biotransformation kuj yog ib feem ntawm xenobiotic metabolism. Yog li ntawd, biotransformation los ntawm ib tug compound mus rau lwm compound yog ib qho tseem ceeb nyob rau hauv thiaj li yuav ntxiv zog xws li solubility rau cov tebchaw, thiab lwm yam.
YYuav ua li cas yog Biotransformation?
Biotransformation yog hais txog kev hloov pauv biochemical uas tshwm sim hauv ib qho chaw tshwj xeeb, tshuaj lossis xenobiotic. Yog li, nws kuj yog ib feem ntawm cov metabolism hauv lub cev. Txawm li cas los xij, biotransformation nruj me ntsis hais txog kev hloov pauv ntawm cov cuab yeej biochemical ntawm ib qho chaw tshwj xeeb hauv kev ua neej nyob. Ib yam li ntawd, cov tshuaj tiv thaiv biotransformation feem ntau tshwm sim hauv cov tshuaj tiv thaiv xenobiotic thaum cov xenobiotics insoluble tau ua rau hauv cov ntaub ntawv soluble thiab sib txuas rau kev thauj mus los. Yog li, cov tshuaj tiv thaiv no poob rau hauv qeb ntawm biotransformation.
Daim duab 01: Biotransformation
Hauv xenobiotic metabolism, biotransformation yog qhov tseem ceeb rau ob lub hom phiaj tseem ceeb. Ua ntej, nws pab kom muaj sia nyob ntawm lub cev los ntawm kev hloov cov khoom noj rau hauv ntau hom. Cov biotransformed as-ham ces yooj yim absorbed los ntawm cov kab mob. Qhov thib ob, biotransformation yog ib qho tseem ceeb rau detoxify cov tshuaj lom, teeb meem tshuaj nkag mus rau hauv lub cev. Yog li ntawd, qhov no ua rau muaj kev vam meej tshem tawm cov teeb meem no los ntawm kev ua neej nyob. Hauv xenobiotic mechanisms, biotransformation muaj ob theem; lawv yog theem I thiab theem II. Txhua theem muaj nws cov haujlwm uas pab txhawb cov txheej txheem xenobiotic.
YMetabolism yog dab tsi?
Metabolism yog hais txog tag nrho cov tshuaj biochemical uas tshwm sim hauv cov kabmob muaj sia. Kev noj qab haus huv metabolism hauv lub cev pab kev loj hlob thiab muaj sia nyob ntawm lub cev. Cov txheej txheem metabolic yog qhov tseem ceeb los tswj kev loj hlob thiab kev loj hlob, tsim lub zog thiab kev txhawb nqa ntawm tag nrho cov khoom ua haujlwm ntawm lub cev. Metabolism nyob rau hauv lub neej yog muab faib ua ob yam tseem ceeb. Lawv yog cov anabolism thiab catabolism. Anabolism yog hais txog cov txheej txheem hluavtaws metabolic uas siv lub zog rau cov txheej txheem synthesis. Yog li, cov txheej txheem metabolic xws li photosynthesis, glycogen synthesis, lipid synthesis yog pawg ntawm cov txheej txheem anabolic. Hauv qhov sib piv, catabolism hais txog cov txheej txheem tawg. Cellular respiration yog txheej txheem catabolic uas tsim lub zog.
Metabolism yog qhov tseem ceeb heev. Cov txheej txheem metabolic txawv ntawm hom rau hom. Cov metabolism hauv lub cev yog nyob ntawm qhov nyuaj ntawm lub cev, ib puag ncig uas lawv nyob hauv, lawv cov caj ces tsim - thiab lawv tus cwj pwm coj. Cov txheej txheem metabolic kuj nyob ntawm seb muaj biocatalysts thiab muaj cov khoom siv raw rau txoj kev metabolic tshwj xeeb. Yog li, qee txoj hauv kev metabolic tsuas muaj nyob hauv qee hom kab mob nyob.
Daim duab 02: Metabolism
Metabolism nyob rau hauv ib lub cev yuav tsum muaj kev sib npaug kom ntseeg tau tias kev noj qab haus huv ntawm lub cev. Yog li, cov kev taw qhia lub cev, cov tshuaj hormones, enzyme regulators thiab yam xws li kub, pH kuj pab tswj cov kev pom zoo metabolic hauv cov kab mob nyob.
Dab tsi yog qhov zoo sib xws ntawm Biotransformation thiab Metabolism?
- Ob txheej txheem tshwm sim hauv cov kab mob muaj sia.
- Lawv ob leeg koom nrog cov tshuaj tiv thaiv biochemical.
- Tsis tas li, ob txoj kev tseem ceeb heev rau kev ciaj sia, kev loj hlob thiab kev loj hlob.
- Ntxiv mus, ob txheej txheem no tseem ceeb hauv xenobiotic metabolism thiab tshuaj metabolism.
- Ntxiv mus, cov txheej txheem no yog enzyme-catalyzed.
- Thiab, ob qho tib si txheej txheem yuav tsum muaj kev taw qhia txoj hauv kev rau kev tswj hwm
Qhov txawv ntawm Biotransformation thiab Metabolism yog dab tsi?
Biotransformation yog hais txog kev hloov pauv biochemical uas tshwm sim hauv ib qho chaw tshwj xeeb, tshuaj lossis xenobiotic. Ntawm qhov tod tes, Metabolism yog hais txog tag nrho cov tshuaj biochemical uas tshwm sim hauv cov kab mob uas muaj sia nyob. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm biotransformation thiab metabolism. Ntxiv mus, lub hom phiaj ntawm txhua tus txheej txheem pab txhawb rau lwm qhov sib txawv ntawm biotransformation thiab metabolism. Qhov ntawd yog; Tsuas yog ib qho kev sib xyaw tshwj xeeb yog tsom rau hauv biotransformation thaum tag nrho cov kab mob koom nrog hauv cov txheej txheem metabolic.
Summary – Biotransformation vs Metabolism
Muaj kab nyias nyias ntawm cov ntsiab lus biotransformation thiab metabolism. Ob leeg muaj xws li biochemical kev tshwm sim tshwm sim ntawm cov molecules nyob rau hauv ib tug nyob system. Txawm li cas los xij, cov metabolism npog ntau qhov loj dua. Nws suav nrog tag nrho cov kev hloov biochemical uas tshwm sim hauv lub cev. Hauv qhov sib piv, biotransformation tsuas yog lub hom phiaj ntawm ib qho molecule lossis tshuaj. Yog li ntawd, biotransformation pab txhawb kev hloov pauv lub cev hauv qhov sib xyaw ua ke uas ua rau muaj kev hloov pauv hauv cov ntsiab lus tshwj xeeb. Li no, qhov no qhia txog qhov sib txawv ntawm biotransformation thiab metabolism.
