Qhov sib txawv tseem ceeb ntawm Pluripotent thiab Induced Pluripotent Stem Cells yog tias cov pluripotent hlwb yog cov niam cov hlwb tsis txawv (los ntawm embryos, thiab lwm yam), uas muaj lub peev xwm los sib txawv rau hauv ntau hom cell whereas lub induced pluripotent qia hlwb yog Cov neeg laus somatic hlwb uas tau raug tshuaj genetic reprogrammed los qhia cov yam ntxwv zoo ib yam li ntuj pluripotent qia hlwb.
Ib lub qia cell yog ib lub xovtooj tsis sib xws uas muaj lub peev xwm tshwj xeeb los txhim kho rau hauv cov hlwb sib txawv lossis tshwj xeeb. Tsis tas li ntawd, cov qia hlwb muaj peb hom xws li unipotent, pluripotent thiab multipotent. Yog tias qia cell tuaj yeem sib txawv rau hauv ib qho, ntau yam, thiab rau txhua hom cell, nws yog hu ua unipotent, multipotent, lossis pluripotent qia cell feem. Ntawm peb hom saum toj no, pluripotent qia hlwb tseem ceeb vim tias lawv tuaj yeem sib txawv rau txhua hom cell. Pluripotent embryonic qia cell tuaj yeem txhim kho rau hauv tib neeg.
Pluripotent Stem Cells yog dab tsi?
Pluripotent qia hlwb yog cov hlwb tsis txawv txav uas muaj peev xwm sib txawv rau hauv thawj peb txheej kab mob. Lawv muaj peev xwm ntawm tus kheej rov ua dua tshiab thiab sib txawv rau txhua hom hlwb hauv lub cev. 'Embryonic qia hlwb' yog cov ntsiab lus dav siv los xa mus rau pluripotent qia hlwb. Ib lub cell uas los ntawm lub embryo tuaj yeem tsim yuav luag txhua hom cell hauv peb lub cev. Txawm li cas los xij, tom qab qee theem, cov hlwb no poob lawv cov pluripotency. Thaum lawv poob nws, lawv dhau los ua ib yam lossis ib hom cell uas tsis tuaj yeem sib txawv ntxiv. Thaum pluripotent qia cell yog kab lis kev cai hauv chav kuaj, lawv hu ua 'pluripotent qia cell kab'.
Daim duab 01: Pluripotent Stem Cell
Muaj ntau hom pluripotent qia hlwb. Ntawm lawv, embryonic qia hlwb yog qhov tseem ceeb tshaj plaws. Ntxiv mus, cov hlwb no tseem ceeb heev hauv kev kho kab mob vim lawv tuaj yeem siv los tsim cov cell noj qab haus huv lossis cov ntaub so ntswg los hloov cov ntaub so ntswg (hloov).
Dab tsi yog Induced Pluripotent Stem Cells?
Induced pluripotent qia hlwb yog hom thib ob ntawm pluripotent qia hlwb. Lawv yog cov reprogrammed hlwb. Lawv tuaj ntawm cov neeg laus somatic hlwb. Lawv cov noob yog reprogrammed los hloov lawv mus rau hauv lub ntuj pluripotent qia hlwb thiab ua raws li txoj kev sib txawv. Induced pluripotent qia hlwb muaj peev xwm kho tau zoo. Thiab lawv kuj pab kawm seb cov kab mob sib txawv li cas thiab yuav kho lawv li cas. Tsis tas li ntawd, lawv tshem tawm cov ntaub so ntswg sib txuam thiab tsis lees txais cov teeb meem thaum hloov pauv.
Daim duab 02: Induced Pluripotent Stem Cells
Kev tsim cov kab mob pluripotent qia hlwb yuav tsum ua tib zoo ua hauv chav kuaj. Ntxiv mus, lawv feem ntau muab tau los ntawm cov hlwb somatic xws li cov hlwb ntawm daim tawv nqaij lossis lwm cov hlwb hauv lub cev. Ntau cov noob tau koom nrog hauv cov txheej txheem tsim khoom, thiab cov kab mob thiab cov kab mob tsis yog siv los qhia cov noob no rau hauv cov hlwb somatic.
Dab tsi yog qhov zoo sib xws ntawm Pluripotent thiab Induced Pluripotent Stem Cells?
- Ob leeg Pluripotent thiab Induced Pluripotent Stem Cells yog cov hlwb tsis sib xws.
- Lawv tuaj yeem hloov kho tus kheej tsis tu ncua hauv kab lis kev cai.
- Ob leeg pluripotent thiab Induced Pluripotent Stem Cells tuaj yeem sib txawv rau txhua hom cell hauv lub cev.
Qhov txawv ntawm Pluripotent thiab Induced Pluripotent Stem Cells yog dab tsi?
Ob leeg pluripotent thiab Induced Pluripotent Stem Cells yog cov hlwb tsis muaj qhov sib txawv uas tuaj yeem sib txawv rau txhua hom cell. Yog li ntawd, qhov sib txawv tseem ceeb ntawm pluripotent thiab induced pluripotent qia hlwb yog tias pluripotent qia hlwb yog ntuj embryonic hlwb thaum induced pluripotent qia hlwb yog reprogrammed somatic hlwb.
Summary – Pluripotent vs Induced Pluripotent Stem Cells
Cov qia hlwb thiab induced pluripotent qia hlwb yog ob hom pluripotent qia hlwb. Ob leeg muaj peev xwm sib txawv rau txhua hom cell. Induced pluripotent qia hlwb yog reprogrammed los yog genetic hloov somatic hlwb. Lawv qhia txog qhov sib txawv ntawm qhov sib txawv xws li embryonic hlwb. Ob lub hlwb muaj txiaj ntsig zoo rau kev kho mob. Qhov no yog qhov txawv ntawm pluripotent qia hlwb thiab induced pluripotent qia hlwb.
