Qhov sib txawv tseem ceeb ntawm neural stem cells thiab neural progenitor cells yog cov neural stem cells yog cov hlwb uas tsis muaj kev cog lus uas muaj peev xwm tsim tau tag nrho cov neural lineages, thaum neural progenitor cells yog cov hlwb cog lus kom nce mus rau ib pawg ntawm neural Cheebtsam..
Neural stem cells thiab neural progenitor cells yog ob hom hlwb hauv nruab nrab paj hlwb. Neural qia hlwb yog cov hlwb rov ua dua tshiab uas muaj peev xwm tsim tau tag nrho cov kab mob neural. Lawv tuaj yeem ua rau cov neurons, astrocytes, thiab oligodendrocytes. Neural progenitor cells tau cog lus tias yuav muab nce rau ib pawg ntawm neural Cheebtsam. Lawv sib txawv rau hauv cheeb tsam thiab thaj tsam sib txawv neurons thiab glial hlwb.
Neural Stem Cells yog dab tsi?
Neural qia hlwb yog cov tsis muaj zog ntau lub hlwb uas muaj peev xwm tsim tau tag nrho cov kab mob neural. Yog li, lawv ua rau cov neurons, astrocytes, thiab oligodendrocytes hauv CNS. Neural qia hlwb tuaj yeem rov ua nws tus kheej. Lawv tsim cov cell loj ntawm cov tsiaj nyeg CNS. Cov hlwb no yog cov hlwb tsis paub tab lossis tsis paub tshwj xeeb.
Daim duab 01: Neural Stem Cells
Neural qia hlwb muaj nyob rau hauv ob lub embryo thiab cov neeg laus lub hlwb. Nyob rau hauv cov neeg laus lub hlwb, neural qia hlwb yog nplua nuj nyob rau hauv subventricular cheeb tsam ntawm lub lateral ventricle. Neural qia hlwb muaj peev xwm kho tau. Lawv ua raws li qhov muaj txiaj ntsig zoo rau kev kho mob txha caj qaum. Tsis tas li ntawd, lawv tau siv los kho mob qog noj ntshav hauv hlwb.
Neural Progenitor Cells yog dab tsi?
Neural progenitor cells yog cov hlwb progenitor ntawm CNS uas tau dhau los ua ib hom kab mob, cog lus tias yuav ua rau tsuas yog ib pawg ntawm neural Cheebtsam. Neural progenitor hlwb sib txawv tsuas yog nyob rau hauv lub regional thiab spatial txawv neurons thiab glial hlwb. Lawv tsis tsim cov hlwb uas tsis yog neural hauv CNS. Neural progenitor cells raug pom nyob rau hauv ob qho tib si tsim embryo thiab cov neeg laus lub hlwb mammalian.
Daim duab 02: Neurogenic Niches hauv lub hlwb
Thaum piv rau neural qia hlwb, neural progenitor cells tsis muaj peev xwm rov ua dua nws tus kheej. Lawv tsuas tuaj yeem dhau los ntawm qhov tsawg kawg ntawm kev rov ua dua. Zoo ib yam li neural stem cells, neural progenitor cells kuj muaj ob lub cim zoo niches hauv cov neeg laus lub hlwb. Lawv yog "subgranular zone (SGZ)" ntawm dentate gyrus thiab "tus neeg laus SVZ" nyob ib puag ncig lub ventricles ntawm lub hlwb cerebral cortex.
Dab tsi zoo sib xws ntawm Neural Stem Cells thiab Neural Progenitor Cells?
- Ob leeg neural stem cells thiab neural progenitor cells yog cov hlwb ntawm CNS.
- Lawv pom nyob rau hauv lub embryo thiab nyob rau hauv cov neeg laus lub hlwb.
- Cov noob qes qes los ntawm cov qia hlwb.
- Ob lub stem cells thiab progenitor cells muaj tus nqi kho mob.
Qhov txawv ntawm Neural Stem Cells thiab Neural Progenitor Cells yog dab tsi?
Neural qia hlwb yog cov cell uas tsis muaj zog tshwj xeeb hauv lub hauv nruab nrab paj hlwb uas tuaj yeem ua rau txhua hom cell ntawm lub hlwb, thaum cov hlwb neural progenitor yog cov cell progenitor hauv nruab nrab paj hlwb, uas tuaj yeem ua rau cov neurons nkaus xwb. thiab glial cells. Neural qia hlwb muaj peev xwm rov ua dua nws tus kheej, thaum cov hlwb neural progenitor tsis tuaj yeem rov ua nws tus kheej. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm neural stem cells thiab neural progenitor cells. Ntxiv mus, neural stem cells tuaj yeem loj hlob yam tsis muaj kev txwv, thaum cov hlwb neural progenitor muaj peev xwm nthuav dav.
Cov hauv qab no infographic teev qhov sib txawv ntawm neural stem cells thiab neural progenitor cells nyob rau hauv daim ntawv tabular rau ib sab sib piv.
Summary – Neural Stem Cells vs Neural Progenitor Cells
Neural qia hlwb yog cov hlwb tsis muaj peev xwm tshwj xeeb hauv lub hauv paus paj hlwb uas tuaj yeem ua rau cov neurons, astrocytes, lossis oligodendrocytes. Neural progenitor cells yog cov hlwb progenitor nyob rau hauv lub hauv nruab nrab lub paj hlwb uas tuaj yeem ua rau thaj tsam thiab thaj tsam sib txawv ntawm cov neurons thiab glial hlwb. Neural qia hlwb yog tus kheej-renewable, thaum neural progenitor hlwb tuaj yeem ua rau muaj tsawg tus lej ntawm kev rov ua dua. Lub niche ntawm neural qia hlwb nyob rau hauv cov neeg laus lub hlwb yog subventricular cheeb tsam ntawm lub lateral ventricle whereas ob niches ntawm neural progenitor hlwb nyob rau hauv cov neeg laus lub hlwb yog lub subgranular cheeb tsam (SGZ) ntawm lub dentate gyrus thiab cov neeg laus subventricular cheeb tsam (SVZ) nyob ib ncig ntawm lub lateral ventricles ntawm cov laus cerebral cortex. Yog li, qhov no yog cov ntsiab lus ntawm qhov sib txawv ntawm neural stem cells thiab neural progenitor cells.
