Qhov sib txawv tseem ceeb ntawm Graves Disease thiab hyperthyroidism yog tias Graves 'tus kab mob yog ib qho mob pathological thaum lub hyperthyroidism yog ib qho kev ua haujlwm tsis zoo uas yog tshwm sim los ntawm cov txheej txheem pathological tsis tu ncua.
Kev nce qib ntawm cov tshuaj thyroxin dawb yog hu ua hyperthyroidism. Hyperthyroidism tuaj yeem yog vim muaj ntau yam ua rau, thiab Graves 'tus kab mob yog ib yam kab mob uas txawv txav nce qib thyroxin hauv lub cev. Graves 'tus kab mob yog txhais tau tias yog ib qho autoimmune thyroid disorder nrog ib qho tsis paub etiology. Nws yog ib qho mob pathological uas ua rau muaj hyperthyroidism uas yog qhov ua haujlwm tsis zoo vim yog cov txheej txheem tsis tu ncua.
Dab tsi yog Graves' Disease ?
Graves 'tus kab mob yog ib qho autoimmune thyroid disorder nrog ib qho tsis paub etiology.
Pathogenesis
Ib autoantibody ntawm IgG hom hu ua "Thyroid Stimulating Immunoglobulin" khi rau TSH receptors hauv cov thyroid caj pas thiab ua raws li kev ua ntawm TSH. Yog li, raws li qhov tshwm sim ntawm qhov kev txhawb zog no, muaj ntau ntau ntawm cov thyroid hormones cuam tshuam nrog hyperplasia ntawm cov thyroid follicular hlwb. Qhov tshwm sim yog qhov nthuav dav ntawm cov thyroid caj pas.
Qhov nce ntxiv los ntawm cov thyroid hormones nthuav qhov ntim ntawm cov ntaub so ntswg retro-orbital. Qhov no nrog edema ntawm cov nqaij ntshiv extraocular, tsub zuj zuj ntawm cov ntaub ntawv extracellular matrix, thiab infiltration ntawm periocular qhov chaw los ntawm lymphocytes thiab cov ntaub so ntswg rog tsis muaj zog cov nqaij ntshiv extraocular, yog li thawb lub qhov muag rau pem hauv ntej.
Morphology
Muaj diffuse o ntawm cov thyroid caj pas. Txiav seem yuav pom liab meaty tsos. Follicular cell hyperplasia uas yog tus cwj pwm los ntawm qhov muaj ntau ntawm cov follicular me me yog cov cim microscopic feature.
Tshuaj Kho Mob
Qhov txawv qhov chaw kho mob ntawm Graves tus kab mob yog,
- Diffuse goiter
- Exophthalmos
- Periorbital myoedema
Ntxiv rau cov tsos mob no, tus neeg mob tuaj yeem muaj cov tsos mob hauv qab no vim tias muaj cov thyroid hormone ntau ntxiv.
- poob phaus thiab nce qab los noj mov
- Zoo plab vim plab zom mov ntau
- Kev mob siab rau lub suab ua rau muaj kev tshee hnyo, pw tsaug zog, ntxhov siab vim thiab cov leeg tsis muaj zog.
- Kev mob plawv: tachycardia, palpitations, thiab arrhythmias.
Kev tshawb nrhiav
- Kev kuaj cov thyroid ua haujlwm kom paub meej tias thyrotoxicosis
- Tshuaj xyuas seb muaj cov thyroid stimulating immunoglobulin hauv cov ntshav.
Daim duab 01: Graves Disease
Kev tswj hwm
kho mob
Kev tswj hwm cov tshuaj tiv thaiv thyroid xws li carbimazole thiab methimazole yog qhov zoo heev. Qhov tshwm sim feem ntau cuam tshuam nrog kev siv cov tshuaj no tas mus li yog agranulocytosis, thiab tag nrho cov neeg mob uas nyob rau hauv cov tshuaj antithyroid yuav tsum tau qhia kom mus nrhiav kev kho mob tam sim ntawd thaum tsis tau piav qhia ua npaws lossis mob caj pas.
- xov tooj cua kho nrog xov tooj cua iodine
- Kev phais ntawm cov thyroid caj pas. Qhov no yog qhov kev xaiv zaum kawg uas tsuas yog siv thaum kev kho mob tsis ua tiav qhov kev xav tau.
YHyperthyroidism yog dab tsi?
Lub xeev ntawm nce qib ntawm cov tshuaj thyroxin dawb yog hu ua hyperthyroidism.
Caus
- Graves' disease
- Toxic multinodular goiter
- Follicular adenoma
- YPituitary qog
- Neonatal hyperthyroidism vim niam txiv Graves disease.
Daim duab 02: Hyperthyroidism
Tshuaj Kho Mob
- Kev nce siab hauv kev ua siab ntev thiab osmolarity yog qhov laj thawj tseem ceeb
- nce basal metabolic tus nqi ua rau txo qis hauv lub cev hnyav nrog tus yam ntxwv nce hauv qab los noj mov.
- Tshem
- Hyperactivity
- Insomnia
- kev ntxhov siab
- Cov leeg tsis muaj zog thiab txo cov leeg nqaij - thyroid myopathy
- Npaj siab mob plab ua rau raws plab
- Tachycardia, palpitations, thiab Kev ua haujlwm ntau ntxiv ntawm cov leeg plawv tuaj yeem ua rau lub plawv tsis ua haujlwm ua rau lub plawv tsis ua haujlwm.
- Osteoporosis vim muaj pob txha resorption
x
Kev tshawb nrhiav
1. Thyroid function test
- Kom paub meej thyrotoxicosis
- Free T4 theem
- Tsis tshua muaj thyrotoxicosis yog vim TSH secreting pituitary qog TSH tuaj yeem nce
2. Radioiodine uptake test
- Diffusely nce uptake nyob rau hauv tag nrho cov qog nyob rau hauv Grave tus kab mob
- Focally nce uptake hauv tshuaj lom adenomas
3. Kev sim rau cov thyroid stimulating immunoglobulins los kuaj mob Graves
Dab tsi yog qhov zoo sib xws ntawm Graves' Kab Mob thiab Hyperthyroidism?
Graves ' kab mob yog ib qho ua rau hyperthyroidism. Yog li, muaj kev nce qib ntawm thyroxin hauv cov ntshav
Qhov txawv ntawm Grave's Disease thiab Hyperthyroidism yog dab tsi?
Graves 'tus kab mob yog ib qho mob pathological thaum hyperthyroidism yog qhov ua haujlwm tsis zoo uas yog tshwm sim los ntawm cov txheej txheem tsis tu ncua. Qhov no yog qhov txawv ntawm Graves kab mob thiab hyperthyroidism. Tsis tas li ntawd, los ntawm kev txhais, Graves kab mob yog ib qho autoimmune thyroid disorder nrog ib qho tsis paub etiology. Ntawm qhov tod tes, Hyperthyroidism yog lub xeev ntawm kev nce qib ntawm cov tshuaj thyroxin dawb hu ua hyperthyroidism. Cov infographic hauv qab no nthuav tawm ntau qhov sib txawv ntawm Graves tus kab mob thiab hyperthyroidism nyob rau hauv daim ntawv tabular raws li lawv cov laj thawj, cov yam ntxwv kho mob, thiab kev tshawb nrhiav.
Summary – Graves Disease vs Hyperthyroidism
Kab mob Graves yog ib yam mob uas tau txhais tias yog ib qho kev mob autoimmune thyroid uas tsis paub txog etiology. Hyperthyroidism yog lub xeev ntawm kev nce qib ntawm cov tshuaj thyroxin dawb uas tuaj yeem yog vim muaj ntau yam ua rau suav nrog tus kab mob Graves. Qhov no yog qhov txawv ntawm Graves kab mob thiab hyperthyroidism.
