Qhov Tseem Ceeb - CML vs CLL
Leukemia tuaj yeem piav qhia hauv cov ntsiab lus raws li cov ntshav tsis zoo. Txawm li cas los xij, qhov tseeb, lub hauv paus chiv keeb ntawm leukemia tshwm sim hauv cov pob txha pob txha uas cov kab mob precursor uas tsim ntau cov qe ntshav. CML (Chronic Myeloid Leukemia) thiab CLL (Chronic Lymphocytic Leukemia) yog ob hom kab mob leukemia uas tshwm sim vim qhov txawv txav ntawm cov qia hlwb hauv cov pob txha pob txha. CML yog ib tug tswv cuab ntawm tsev neeg ntawm myeloproliferative neoplasms whereas CLL yog hom kab mob leukemia uas nws lub hauv paus pathological yog clonal expansion ntawm B hlwb. Hauv CML, cov hlwb malignant yog granulocytes lossis myelocytes thaum nyob hauv CLL, lymphocytes yog cov qe ntshav uas muaj cov yam ntxwv tsis zoo. Qhov no yog qhov txawv ntawm CML thiab CLL.
CML yog dab tsi?
CML (Chronic Myeloid Leukemia) yog ib tus tswv cuab ntawm tsev neeg ntawm myeloproliferative neoplasms uas tshwm sim tshwj xeeb rau cov neeg laus. Nws yog txhais los ntawm lub xub ntiag ntawm Philadelphia chromosome thiab muaj kev kawm qeeb qeeb dua li mob qog noj ntshav.
Tshuaj Kho Mob
- Symptomatic anemia
- mob plab tsis xis nyob
- poob qis
- Headache
- YLymphadenopathy
Daim duab 01: Tsim Philadelphia Chromosome
Kev tshawb nrhiav
- ntshav suav - Hemoglobin qis lossis ib txwm muaj. Platelets yog qis, zoo li qub lossis tsa. WBC suav tau nce.
- Kev muaj tus paub tab myeloid precursors hauv ntshav zaj duab xis
- Kev nce cellularity nrog nce myeloid precursors hauv pob txha pob txha aspirate.
Kev tswj hwm
Thawj kab tshuaj hauv kev kho mob ntawm CML yog Imatinib (Glivec), uas yog tyrosine kinase inhibitor. Cov kab mob thib ob suav nrog kev siv tshuaj khomob nrog hydroxyurea, alpha interferon, thiab kev hloov pauv ntawm cov qia hlwb allogeneic.
CLL yog dab tsi?
CLL (Chronic Lymphocytic Leukemia) yog hom kab mob leukemia ntau tshaj plaws, thiab feem ntau tshwm sim rau cov neeg laus. Lub clonal expansion ntawm me B lymphocytes yog lub hauv paus pathological ntawm tus mob no.
Tshuaj Kho Mob
- Asymptomatic lymphocytosis
- YLymphadenopathy
- Marrow tsis ua haujlwm
- YHepatosplenomegaly
- B-symptoms
Kev tshawb nrhiav
- Cov qe ntshav dawb siab heev tuaj yeem pom hauv cov ntshav suav
- Smudge cells tuaj yeem pom hauv cov ntshav zaj duab xis
Daim duab 02: Chronic Lymphocytic Leukemia (CLL)
Kev tswj hwm
Kev kho yog muab rau cov teeb meem organomegaly, ntu hemolytic, thiab pob txha pob txha. Rituximab ua ke nrog Fludarabine thiab cyclophosphamide qhia cov lus teb zoo heev.
CML thiab CLL yog dab tsi?
Ob CML thiab CLL yog qhov phem nrog tus nqi sib kis qeeb
Qhov txawv ntawm CML thiab CLL yog dab tsi?
CML vs CLL |
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| CML yog ib tug tswv cuab ntawm tsev neeg ntawm myeloproliferative neoplasms uas tsuas yog tshwm sim rau cov neeg laus. Nws yog txhais los ntawm lub xub ntiag ntawm Philadelphia chromosome. | CLL yog hom kab mob leukemia, thiab nws tshwm sim hauv cov neeg laus feem ntau. Lub clonal expansion ntawm me B lymphocytes yog lub hauv paus pathological ntawm tus mob no. |
| Cancerous Cells | |
| Granulocytes yog cov qog nqaij hlav cancer. | Lymphocytes yog cov qog nqaij hlav cancer. |
| Tshuaj kho mob | |
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Cov yam ntxwv ntawm CML yog, · Symptomatic anemia · plab tsis xis nyob · poob ceeb thawj · mob taub hau · Bruising thiab los ntshav · Lymphadenopathy |
Cov yam ntxwv ntawm CLL yog, · Asymptomatic lymphocytosis · Lymphadenopathy · mob plab tsis ua hauj lwm · Hepatosplenomegaly · B-symptoms |
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· hemoglobin qis lossis ib txwm muaj. · Platelets qis, ib txwm lossis loj. WBC suav tau nce. · mature myeloid precursors muaj nyob rau hauv cov ntshav films. · nce cellularity nrog nce myeloid precursors nyob rau hauv cov pob txha pob txha aspirate. |
Cov qe ntshav dawb siab heev tuaj yeem pom hauv cov ntshav suav. Smudge cells tuaj yeem pom hauv cov yeeb yaj kiab. |
| Kev tswj hwm | |
| Kev kho yog muab rau cov teeb meem organomegaly, ntu hemolytic, thiab pob txha pob txha. Rituximab ua ke nrog Fludarabine thiab cyclophosphamide qhia cov lus teb zoo heev. | Thawj kab tshuaj hauv kev kho mob ntawm CML yog Imatinib (Glivec), uas yog tyrosine kinase inhibitor. Cov kab mob thib ob suav nrog kev siv tshuaj khomob nrog hydroxyurea, alpha interferon, thiab kev hloov pauv ntawm cov qia hlwb allogeneic. |
Summary – CML vs CLL
CML lossis Chronic Myeloid Leukemia yog ib hom kab mob leukemia uas feem ntau pom ntawm cov neeg laus. Ntawm qhov tod tes, Chronic Lymphocytic Leukemia (CLL) yog lwm hom kab mob leukemia uas nws lub hauv paus pathological yog qhov txawv txav hauv kev nthuav dav ntawm B lymphocytes. Qhov sib txawv tseem ceeb ntawm CML thiab CLL yog nyob rau hauv CML, granulocytes yog cov hlwb malignant tab sis lymphocytes yog cov hlwb malignant hauv CLL.
Download PDF Version of CML vs CLL
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li daim ntawv ceeb toom. Thov download PDF version ntawm no Qhov txawv Ntawm CML thiab CLL
