Qhov Tseem Ceeb - Amenorrhea vs Menopause
Amenorrhea tuaj yeem txhais tau tias tsis muaj kev coj khaub ncaws. Txawm li cas los xij, thaum cev xeeb tub, lactation, thiab menopause, kev coj khaub ncaws tsis tshwm sim thiab qhov tsis muaj kev coj khaub ncaws hauv cov xwm txheej no tsis suav tias yog amenorrhoea. Menopause yog qhov kev txiav tawm ntawm kev coj khaub ncaws kwv yees thaum muaj hnub nyoog 52 xyoos, thiab nws sawv cev rau qhov kawg ntawm tus poj niam lub neej yug menyuam. Yog li, qhov sib txawv tseem ceeb ntawm amenorrhea thiab menopause yog tias menopause yog ib qho txheej txheem physiological, thaum amenorrhea yog ib yam kab mob uas yuav tsum tau kho kom raug.
Amenorrhea yog dab tsi?
Amenorrhea yog qhov tsis muaj kev coj khaub ncaws thiab nws tau muab faib ua ob pawg ua thawj thiab theem nrab amenorrhea.
Yog ib tug ntxhais tsis coj khaub ncaws thaum muaj hnub nyoog 16 xyoo, nws hu ua thawj amenorrhea. Yog hais tias ib tug poj niam ntawm lub hnub nyoog yug me nyuam tsis ua poj niam rau 6 lub hlis sib law liag, nws hu ua Secondary amenorrhea.
Daim duab 01: Lub voj voog ib txwm coj khaub ncaws
Caus
Ua rau amenorrhea tuaj yeem muab faib ua plaub pawg raws li kev mob anatomical, zes qe menyuam, mob pituitary thiab hypothalamic mob.
Kev tsis sib haum xeeb ntawm lub cev
- Qhov chaw mos abnormalities
- Mullerian agenesis
- Asherman's Syndrome
- Transverse vaginal septum formation
- Nyob zoo ib tsoom niam txiv kwv tij neej tsas sawv daws.
Asherman's syndrome yog qhov muaj adhesions nyob rau hauv lub tsev me nyuam vim yog lub tsev menyuam loj heev thiab muaj zog heev. Mullerian agenesis yog ib qho kev tsis sib haum xeeb uas tshwm sim los ntawm qhov tsis zoo ntawm qhov chaw mos thiab tsis muaj lub tsev menyuam.
Ovarian Disorders
- Polycystic ovarian syndrome (PCOS)
- Lub zes qe menyuam ua tsis tiav (POF)
POF yog qhov kev ncua ntawm kev coj khaub ncaws ua ntej plaub caug xyoo.
YPituitary Disorders
Ypituitary necrosis thiab adenomas
Prolactinoma yog qhov tshwm sim ntau tshaj plaws ntawm adenoma pom hauv qog pituitary. Pituitary necrosis tshwm sim nyob rau hauv Sheehan syndrome qhov twg hypovolemia thib ob mus rau tom qab lub hemorrhage txo cov perfusion mus rau pituitary caj pas ua rau ischemia thiab necrosis ntawm caj pas.
Hypothalamic Disorders
Cov no tuaj yeem cuam tshuam ncaj qha lossis tsis ncaj qha cuam tshuam rau gonadotropin secretion ua rau muaj qhov tsis txaus ntawm cov tshuaj hormones uas ua rau amenorrhea.
- Kev ntxhov siab, kev tawm dag zog ntau dhau thiab poob phaus tuaj yeem cuam tshuam qhov kev txhawb nqa hypothalamic ntawm pituitary.
- mob taub hau
- Cov kab mob Hypothalamic zoo li craniopharyngioma thiab glioma.
Lwm Yam Uas
- Tshuaj zoo li progesterone, Hormone replacement therapy, dopamine antagonists
- Cov kab mob xws li sarcoidosis, TB
Kev tshawb nrhiav
Nws yog ib qho tseem ceeb uas yuav tau ua keeb kwm kom raug thiab tshuaj xyuas tus neeg mob kom zoo ua ntej xav txog kev tshawb xyuas.
- Ntshav LH, FSH thiab testosterone qib tuaj yeem kuaj xyuas. Nce LH thiab testosterone qib qhia tias polycystic zes qe menyuam syndrome thaum nce FSH qib qhia tias zes qe menyuam ntxov ntxov.
- Yog xav tias muaj prolactinoma, qib prolactin yuav tsum ntsuas.
- Polycystic zes qe menyuam tuaj yeem kuaj pom los ntawm ultrasound
- Kev kuaj xyuas magnetic resonance tuaj yeem ua tau yog tias cov tsos mob qhia pom ntawm pituitary adenoma.
- Yog tias Asherman's syndrome lossis lub ncauj tsev menyuam stenosis xav tias, hysteroscopy tuaj yeem ua tiav.
Kev tswj hwm
Kev tswj tus mob amenorrhea txawv raws li tus kab mob hauv qab.
- Kev noj zaub mov muaj lus qhia thiab kev txhawb nqa yog tias tus kab mob amenorrhea yog vim qhov kev loj hlob qeeb.
- Cov kab mob Hypothalamic zoo li glioma tuaj yeem raug kho los ntawm kev phais. Prolactinoma tuaj yeem kho nrog dopamine agonists zoo li cabergoline lossis bromocriptine. Yog tias tus neeg mob tsis teb cov tshuaj no, kev phais yuav tsum tshem tawm prolactinoma.
- Hommon hloov kho lossis Cyclic Oral Contraceptive Pills (COCP) tuaj yeem siv los kho POF.
- Yog tus neeg mob muaj Asherman's syndrome, adhesiolysis, thiab intrauterine ntaus ntawv yog nqa tawm thaum lub sij hawm hysteroscopy.
- Cervical stenosis yog kho los ntawm ncauj tsev menyuam dilatation thiab hysteroscopy.
- COCP thiab Cyclic Oral Progesterone uas tswj kev coj khaub ncaws tuaj yeem raug sau rau tus neeg mob uas muaj mob Polycystic Ovarian Syndrome. Yog tias tus neeg mob muaj hyperinsulinemia thiab cov kab mob plawv, metformin yuav tsum siv es tsis txhob COCP thiab COP.
Menopause yog dab tsi?
Qhov kev txiav txim ntawm kev coj khaub ncaws ntawm tus poj niam kwv yees li ntawm 52 xyoo yog lub npe hu ua menopause. Nws qhia txog qhov kawg ntawm tus poj niam lub neej kev yug me nyuam.
Yuav kom paub meej tias tus neeg mob tau dhau los lawm, yuav tsum muaj amenorrhea ntawm kaum ob lub hlis sib law liag. Kev phais mob menopause tuaj yeem tshwm sim thaum zes qe menyuam raug tshem tawm thaum lub sijhawm hysterectomy rau malignancy lossis endometriosis hnyav. Tshuaj kho mob thiab kho nrog GnRH analogs yog lwm yam iatrogenic ua rau menopause.
Pathophysiology
Tib neeg lub zes qe menyuam muaj ob thaj chaw sib txawv: sab nraud cortex thiab sab hauv medulla. Sab nrauv cortex feem ntau muaj cov follicles hauv ntau theem ntawm kev loj hlob thiab sab hauv medulla muaj cov hlab ntsha. Muaj cov stromal hlwb tawg thoob plaws hauv lub zes qe menyuam ua peb txoj haujlwm tseem ceeb. Cov haujlwm no ntawm stromal hlwb,
- Txhawb nqa cov ntaub so ntswg zes qe menyuam
- Tsim cov tshuaj steroids
- Mature rau hauv cov hlwb uas nyob ib puag ncig cov hauv paus hniav.
Ovaries tsim plaub yam tshuaj hormones - estradiol, progesterone, testosterone thiab androstenedione.
Nyob hauv utero, muaj txog 1.5 lab primordial follicles hauv zes qe menyuam. Tab sis feem ntau ntawm cov follicles degenerate yam tsis ncav cuag qhov loj hlob thiab tsuas yog txog plaub puas follicles ovulate nyob rau hauv lub cev xeeb tub ntawm ib tug poj niam. Thaum tus naj npawb ntawm cov follicles hauv zes qe menyuam poob qis dua ib theem, estrogen ntau lawm irreversibly poob. Thaum qhov no tshwm sim, tsis muaj qhov tsim nyog hormonal stimulation los txhim kho endometrial proliferation thiab, menopause teem nyob rau hauv.
Txoj Kev Menopause
Qhov cuam tshuam ntawm kev noj zaub mov txawv ntawm ib tus neeg rau ib tus neeg. Qee tus poj niam yuav tsis muaj tsos mob thaum lwm tus tuaj yeem muaj cov tsos mob tsis zoo uas cuam tshuam rau lawv lub neej niaj hnub.
Cov tsos mob tau pom thaum thawj tsib xyoos ntawm kev ua tsis tiav
- Vasomotor cov tsos mob xws li kub hnyiab, hmo ntuj tawm hws
- Cov tsos mob ntawm lub hlwb xws li lub siab lub ntsws, kev ntxhov siab, kua muag, poob siab, nco tsis zoo, thiab poob libido.
- Hair change
- Daim tawv nqaij hloov
- mob pob qij txha
Cov tsos mob tau pom nyob nruab nrab ntawm 3 txog 10 xyoo ntawm lub cev tsis muaj zog, teeb meem Urogenital xws li
- vaginal dryness,
- mob,
- dyspareunia,
- sensory ceev,
- Recurrent UTI,
- YUrogenital prolapse,
- vaginal atrophy
Menopause kuj tuaj yeem cuam tshuam mus ntev xws li pob txha pob txha, kab mob plawv, thiab dementia.
Daim duab 02: Cov tsos mob thiab cov tsos mob ntawm Menopause
Kev tswj hwm
Raws li menopause yog ib qho kev tshwm sim ntawm kev kho mob tsis yog feem ntau yuav tsum tau. Tab sis kev paub txog cov teeb meem mus sij hawm ntev xws li osteoporosis thiab kab mob plawv yuav tsum tau txhim kho.
Hormone replacement therapy (HRT) yog qhov kev kho mob tseem ceeb rau kev cuam tshuam rau kev mob menopausal. Nws hloov cov tshuaj hormones uas ib txwm ua rau tib neeg nyob rau theem physiological. Estrogen yog cov tshuaj hormones tseem ceeb uas tau ntxiv los ntawm HRT. Nws tuaj yeem muab ib leeg lossis ua ke nrog progesterone. Cov tsos mob ntawm vasomotor, cov tsos mob ntawm urogenital, thiab kev sib deev tsis zoo tuaj yeem txo tau los ntawm kev kho mob txuas ntxiv nrog HRT. Tab sis qhov teeb meem loj ntawm kev hloov tshuaj hormone yog tias nws ua rau muaj kev pheej hmoo ntawm thromboembolism thiab mob qog noj ntshav mis.
Dab tsi zoo sib xws ntawm Amenorrhea thiab Menopause?
- Menopause thiab amenorrhea tshwm sim vim qhov kev tso tawm ntawm ovulation.
- HRT tuaj yeem siv los kho ob qho tib si menopause thiab amenorrhea.
- Nyob rau ob lub sijhawm, muaj cov tshuaj hormonal tsis txaus.
Qhov txawv ntawm Amenorrhea thiab Menopause yog dab tsi?
Amenorrhea vs Menopause |
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Amenorrhea yog qhov tsis muaj kev coj khaub ncaws. | Menopause is the end of the menstruation of poj niam. |
Amenorrhea yog ib qho mob pathological | Menopause is a physiological condition |
Kev tswj hwm | |
Kev tswj hwm kev hloov pauv raws li qhov hauv paus ntsiab lus. | Qhov no feem ntau yog tswj hwm nrog HRT. |
Summary – Amenorrhea vs Menopause
Menopause thiab amenorrhea yog ob yam mob ntsig txog kev coj khaub ncaws. Amenorrhea yog qhov tsis muaj poj niam thaum cev xeeb tub yog qhov kawg ntawm kev coj khaub ncaws, cim qhov kawg ntawm lub hnub nyoog ntawm tus poj niam. Ob qho xwm txheej no tshwm sim vim kev txiav tawm ntawm ovulation. Txawm li cas los xij, qhov sib txawv ntawm amenorrhea thiab menopause yog tias menopause yog ib qho txheej txheem physiological, whereas amenorrhea yog ib qho mob pathological.
Download PDF Version of Amenorrhea vs Menopause
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li cov ntawv sau tseg. Thov download PDF version ntawm no Qhov txawv Ntawm Amenorrhea thiab Menopause.