Agglutination vs Coagulation
Agglutination thiab coagulation yog ob lub ntsiab lus uas tsis tshua muaj tshwm sim tshwj tsis yog koj tsis yog kws kho mob. Ob lo lus no hais txog ob qhov xwm txheej sib txawv; Txawm li cas los xij, agglutination tsuas yog ib feem me me hauv coagulation cascade.
Kev sib haum xeeb
Agglutination yog txheej txheem ntawm clumping ntawm cov khoom. Muaj ntau yam piv txwv ntawm agglutination. Hemagglutination yog los ua ke ntawm cov qe ntshav liab. Leukoagglutination yog qhov sib txuam ntawm cov qe ntshav dawb. Cov kab mob antigens agglutinate nrog cov tshuaj tiv thaiv ua rau kev kuaj mob yooj yim dua. Cov ntshav pab pawg yog lwm qhov piv txwv uas siv agglutination los kuaj mob. Muaj cov txheej txheem nyuaj tom qab cov khoom no los ua ke thiab tsim ib pawg.
Cells muaj receptors ntawm lawv qhov chaw. Cov receptors khi nrog kev xaiv cov molecules sab nraum lub hlwb. Cov ntshav pab pawg yog ib qho piv txwv zoo uas siv tau los piav qhia qhov yooj yim no. Muaj plaub hom ntshav loj. Lawv yog A, B, AB thiab O. A, B thiab AB hais txog qhov muaj cov tshuaj tiv thaiv tshwj xeeb (A antigen, B antigen) ntawm cov cell liab. O txhais tau hais tias tsis muaj A lossis B antigen ntawm cov cell liab. Yog tias A antigen muaj nyob rau ntawm cov cell liab, anti-A antibody tsis nyob rau hauv plasma. Cov ntshav B muaj cov tshuaj tiv thaiv-A hauv plasma. AB cov ntshav tsis muaj ib yam. O cov ntshav muaj ob hom kab mob A thiab B. Ib qho antigen khi nrog A-antibody. Thaum cov ntshav B sib xyaw nrog cov ntshav A, vim muaj cov tshuaj tiv thaiv A hauv plasma, cov hlwb liab khi nrog cov tshuaj tiv thaiv no. Ntau tshaj ib lub xov tooj liab khi nrog ib qho tshuaj tiv thaiv, yog li muaj kev sib txuas; qhov no yog lub hauv paus ntawm cov hlwb liab los ua ke. Nov yog lub hauv paus ntawm clumping.
Coagulation yog txheej txheem ntawm cov ntshav txhaws. Clotting muaj peb kauj ruam loj. Lawv yog platelet plug tsim, intrinsic los yog extrinsic pathways, thiab txoj kev uas muaj. Kev raug mob rau cov platelets thiab cov hlwb endothelial hauv cov hlab ntsha tso tawm cov tshuaj, uas ua rau thiab ua kom cov platelets sib sau. Kev raug mob rau cov hlwb tso tawm histamine ua ntej. Tom qab ntawd lwm cov tshuaj kho mob xws li serotonin, cov proteins tseem ceeb, prostaglandin, prostacyclin, leukotrienes, thiab platelet ua yeeb yam tuaj rau hauv kev ua si. Vim cov tshuaj no, muaj ib qho agglutination ntawm platelets. Qhov kawg tshwm sim yog tsim ntawm platelet plug.
Kev nthuav tawm ntawm cov khoom siv hluav taws xob ntxiv ntawm cov cellular matrix ua rau ob txoj kev sib txuas, uas yog txoj hauv kev sab hauv thiab sab hauv. Ob txoj hauv kev no xaus los ntawm kev ua kom muaj txiaj ntsig X. Factor X ua kom yog thawj kauj ruam ntawm txoj hauv kev. Txoj hauv kev zoo tshaj plaws ua rau kev tsim cov fibrin mesh, uas cov qe ntshav tau raug daig, thiab cov ntshav txhaws tau tsim.
Qee yam kab mob cuam tshuam rau coagulation. Hemophilia yog ib qho mob uas tsis muaj coagulation yam ua rau cov ntshav txhaws tsis zoo thiab los ntshav ntau dhau. Cov ntshav txhaws tsis zoo thiab tsis tsim nyog ua rau muaj kev puas tsuaj loj xws li mob stroke thiab myocardial infarction.
Qhov txawv ntawm Agglutination thiab Coagulation yog dab tsi?
• Agglutination txhais tau hais tias sib sau ua ke ntawm cov khoom thaum coagulation txhais tau tias tsim cov ntshav txhaws.
• Ntau cov khoom tuaj yeem ua rau cov ntshav tsuas yog coagulate.
• Agglutination yog vim muaj cov tshuaj tiv thaiv antigen-antibody thaum coagulation yog vim ua kom muaj ntau yam plasma yam.
