Qhov sib txawv tseem ceeb ntawm Mycobacterium tuberculosis thiab Mycobacterium leprae yog qhov Mycobacterium tuberculosis yog tus kab mob ua rau tuberculosis thaum Mycobacterium leprae yog tus kab mob ua rau Hansen tus kab mob (leprosy).
Tsev neeg Mycobacteriaceae suav nrog ib lub genus hu ua Mycobacterium nrog ntau dua 190 hom. Cov kab mob hauv tsev neeg muaj cov kab mob xws li Mycobacterium tuberculosis, Mycobacterium leprae, thiab Mycobacterium abscessus, nrog rau cov kab mob uas tsis yog kab mob xws li Mycobacterium smegmatis thiab Mycobacterium thermoresistibile. Mycobacterium tuberculosis thiab Mycobacterium leprae yog ob hom kab mob sib kis ntawm Mycobacteriaceae.
Mycobacterium Tuberculosis yog dab tsi?
Mycobacterium tuberculosis yog hom kab mob pathogenic uas nyob hauv tsev neeg Mycobacteriaceae. Hom kab no yog tus kab mob ua rau tuberculosis. Nws tau pom thawj zaug hauv xyoo 1882 los ntawm Robert Koch. M. tuberculosis muaj cov waxy txheej txawv txawv ntawm nws lub xov tooj ntawm tes vim muaj mycolic acid. Cov waxy txheej no ua rau cov hlwb impervious rau Gram staining. Vim li no, M. tuberculosis zoo li tsis muaj zog gram-zoo. Ntxiv mus, acid-ceev stains xws li Ziel-Neelsen los yog fluorescent stains xws li auramine yog nquag siv los txheeb xyuas M. tuberculosis. Lub genome ntawm cov kab mob no tau tshwm sim thawj zaug hauv xyoo 1998 los ntawm kev siv cov kab mob H37Rv. Lub genome ntawm hom no yog 4, 411, 532 lub hauv paus khub (4.4 lab lub hauv paus khub) loj nrog 3993 noob.
Daim duab 01: Mycobacterium tuberculosis
M. tuberculosis yog aerobic heev thiab xav tau cov pa oxygen ntau. Nws yog feem ntau yog ib tug pathogen ntawm mammalian ua pa system. Nws kis rau lub ntsws. M. tuberculosis hom tuaj yeem kuaj tau los ntawm kev kuaj tuberculin daim tawv nqaij, acid-ceev stain, kab lis kev cai, thiab cov tshuaj tiv thaiv polymerase saw. Tsis tas li ntawd, cov tshuaj tiv thaiv BCG uas tau txais los ntawm Mycobacterium bovis muaj txiaj ntsig zoo rau cov menyuam yaus thiab cov kab mob hnyav. Txawm li cas los xij, cov tshuaj tiv thaiv no tau txwv tsis pub muaj kev vam meej hauv kev tiv thaiv kab mob uas muaj ntau tshaj plaws ntawm cov kab mob ntsws, cov neeg laus pulmonary tuberculosis.
YMycobacterium Leprae yog dab tsi?
Mycobacterium leprae yog ib hom kab mob hauv tsev neeg ntawm Mycobacteriaceae, uas yog tus kab mob ua rau Hansen tus kab mob (mob ruas). Nws yog ib hom kab mob sib kis uas ua rau cov hlab ntsha peripheral puas tsuaj, uas ua rau cov tawv nqaij, qhov muag, qhov ntswg, thiab cov leeg. Cov kab mob no tseem hu ua leprosy bacillus lossis Hansen's bacillus. Tus kab mob no tau tshawb pom los ntawm Norwegian tus kws kho mob Gerhard Armauer Hansen hauv xyoo 1873 thaum nws tab tom tshawb nrhiav cov kab mob hauv daim tawv nqaij nodules ntawm cov neeg mob ruas. Leprosy tuaj yeem tshwm sim nyob rau txhua theem, txij thaum yau mus rau cov neeg laus.
Daim duab 02: Mycobacterium leprae
Kev kuaj mob ntawm M. leprae tuaj yeem ua los ntawm kev kuaj lub cev, kuaj tawv nqaij, thiab kab lis kev cai. Cov kev kho mob rau tus kab mob no muaj xws li rifampicin thiab clofazimin. Ntxiv mus, qhov no yog thawj kab mob uas tau txheeb xyuas tias yog tus kab mob ua rau tib neeg. Tsis tas li ntawd, lub genome loj ntawm hom no yog 3, 268 203 lub hauv paus khub nrog 1614 noob.
Dab tsi zoo sib xws ntawm Mycobacterium Tuberculosis thiab Mycobacterium Leprae?
- tuberculosis thiab M. leprae yog ob hom kab mob uas nyob hauv tsev neeg Mycobacteriaceae.
- Lawv yog gram-positive.
- Ob hom yog cov kab mob acid-ceev ceev hauv lub cev.
- Lawv cov genomes tau ua tiav thawj zaug hauv xyoo 1998.
Qhov txawv ntawm Mycobacterium Tuberculosis thiab Mycobacterium Leprae yog dab tsi?
M. Tuberculosis yog tus kab mob ua rau tuberculosis, thaum M. leprae yog tus kab mob ntawm Hansen tus kab mob (mob ruas). Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm Mycobacterium tuberculosis thiab Mycobacterium leprae. Tsis tas li ntawd, genome loj ntawm M. tuberculosis yog 4, 411, 532 puag khub, thaum lub genome loj ntawm M. leprae yog 3, 268, 203 puag khub.
Cov ntawv qhia hauv qab no nthuav tawm qhov sib txawv ntawm Mycobacterium tuberculosis thiab Mycobacterium leprae hauv daim ntawv teev npe rau kev sib piv ntawm ib sab.
Summary – Mycobacterium Tuberculosis vs Mycobacterium Leprae
Mycobacterium tuberculosis thiab Mycobacterium leprae yog ob hom kab mob sib cais raws li genus Mycobacterium, uas yog tsev neeg Mycobacteriaceae. M. tuberculosis ua rau tuberculosis, thaum M. leprae ua rau Hansen tus kab mob (mob ruas). Yog li, qhov no yog cov ntsiab lus ntawm qhov sib txawv ntawm Mycobacterium tuberculosis thiab Mycobacterium leprae.