Qhov txawv ntawm Bohr Effect thiab Haldane Effect yog dab tsi

2024 Tus sau: Alex Aldridge | [email protected]. Kawg hloov kho: 2023-12-17 13:40

Qhov sib txawv tseem ceeb ntawm Bohr effect thiab Haldane nyhuv yog qhov Bohr nyhuv yog qhov txo qis ntawm hemoglobin cov pa khi rau hauv lub peev xwm, ua rau muaj kev nce hauv cov pa roj carbon dioxide concentration lossis txo pH, thaum cov nyhuv Haldane yog qhov txo qis ntawm hemoglobin. carbon dioxide binding muaj peev xwm, ua rau kom muaj oxygen concentration.

Hemoglobin yog tsim los ntawm plaub subunits. Nws tuaj yeem khi txog li plaub lub molecules oxygen ib zaug. Cov pa roj carbon dioxide qib, pH ntawm cov ntshav, qhov kub thiab txias ntawm cov ntshav, ib puag ncig, thiab cov kab mob tuaj yeem cuam tshuam rau nws cov hemoglobin lub peev xwm nqa oxygen thiab xa khoom. Tsis tas li ntawd, cov nyhuv Bohr thiab Haldane nyhuv yog ob qhov tshwm sim cuam tshuam rau hemoglobon lub peev xwm nqa oxygen.

Bohr Effect yog dab tsi?

Cov nyhuv Bohr yog qhov tshwm sim thawj zaug tau piav qhia los ntawm Danish physiologist Christian Bohr hauv xyoo 1904. Raws li qhov tshwm sim no, hemoglobin cov pa binding affinity yog inversely cuam tshuam rau ob qho tib si acidity thiab concentration ntawm carbon dioxide. Cov nyhuv Bohr yog qhov txo qis ntawm hemoglobin lub peev xwm oxygen binding nrog kev nce hauv carbon dioxide concentration lossis txo pH. Yog li ntawd, cov nyhuv Bohr hais txog kev hloov pauv ntawm cov pa oxygen dissociation nkhaus los ntawm kev hloov pauv hauv cov concentration ntawm CO_{2lossis pH ntawm ib puag ncig.}

Vim CO₂ reacts nrog dej thiab tsim carbonic acid, nce hauv CO_{2 ua rau cov ntshav pH poob qis. Thaum kawg, qhov no tshwm sim hauv qhov txo qis ntawm hemoglobin cov pa oxygen khi lub peev xwm vim hemoglobin proteins tso lawv cov pa oxygen. Piv txwv li, thaum muaj qhov txo qis hauv carbon dioxide, nws provokes qhov nce hauv pH, uas ua rau muaj qhov nce ntawm hemoglobin lub peev xwm ntawm cov pa oxygen vim hemoglobin khaws cov pa ntau dua. Tsis tas li ntawd, cov nyhuv Bohr tseem ceeb heev vim tias nws txhim kho cov pa oxygen rau cov leeg thiab cov ntaub so ntswg qhov twg cov metabolism tshwm sim. Qhov no yog qhov tseem ceeb heev vim tias cov nyhuv Bohr pab xa cov pa oxygen mus rau thaj chaw uas nws xav tau tshaj plaws.}

Haldane Effect yog dab tsi?

Cov nyhuv Haldane yog qhov txo qis ntawm hemoglobin cov pa roj carbon dioxide binding muaj peev xwm nrog kev nce hauv cov pa oxygen. Cov nyhuv Haldane yog cov cuab yeej ntawm hemoglobin. Qhov tshwm sim no tau piav qhia thawj zaug los ntawm John Scott Haldane hauv xyoo 1914. John Scott Haldane yog ib tus kws kho mob Scottish thiab kws kho mob lub cev nto moo rau ntau yam ntawm nws qhov tseem ceeb nrhiav pom txog tib neeg lub cev thiab qhov xwm txheej ntawm cov pa roj.

Cov pa oxygenation ntawm cov ntshav hauv lub ntsws hloov CO ₂ los ntawm hemoglobin, nce kev tshem tawm CO _2. Kev sib raug zoo rau CO₂ hauv cov ntshav oxygenated tsawg. Yog li ntawd, cov nyhuv Haldane piav qhia txog lub peev xwm ntawm hemoglobin kom nqa tau ntau dua CO ₂hauv lub xeev deoxygenated uas tsis yog lub xeev oxygenated. Ntxiv mus, qhov siab ntawm CO₂ pab txhawb kev sib cais ntawm oxyhemoglobin. Qhov tshwm sim no piav qhia tias yog vim li cas cov neeg mob uas muaj kab mob ntsws tsis tuaj yeem ua rau muaj qhov ua pa alveolar nyob rau hauv lub ntsej muag ntawm CO₂

Dab tsi zoo sib xws ntawm Bohr Effect thiab Haldane Effect?

• Bohr effect thiab Haldane effect yog ob qhov tshwm sim uas cuam tshuam rau hemoglobon lub peev xwm nqa oxygen.
• Ob qhov teebmeem yog cov khoom ntawm hemoglobin.
• Lawv muaj qhov tseem ceeb hauv kev kho mob.
• Ob qhov teebmeem tau pom thaum pib ntawm 19^th.

Qhov txawv ntawm Bohr Effect thiab Haldane Effect yog dab tsi?

Bohr nyhuv yog qhov txo qis ntawm hemoglobin lub peev xwm oxygen khi nrog kev nce hauv cov pa roj carbon dioxide los yog txo qis hauv pH, thaum cov nyhuv Haldane yog qhov txo qis ntawm hemoglobin cov pa roj carbon dioxide binding peev nrog kev nce hauv cov pa oxygen. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm Bohr Effect thiab Haldane Effect.

Cov lus hauv qab no qhia txog qhov sib txawv ntawm Bohr Effect thiab Haldane Effect.

Summary – Bohr Effect vs Haldane Effect

Bohr nyhuv thiab Haldane nyhuv yog ob qhov tshwm sim ntsig txog hemoglobon lub peev xwm nqa oxygen. Cov nyhuv Bohr yog qhov txo qis hauv hemoglobin lub peev xwm oxygen nrog rau kev nce hauv cov pa roj carbon dioxide concentration lossis txo pH. Lub caij no, cov nyhuv Haldane yog qhov txo qis hauv hemoglobin cov pa roj carbon dioxide khi lub peev xwm nrog kev nce hauv cov pa oxygen. Yog li, qhov no qhia txog qhov sib txawv ntawm Bohr effect thiab Haldane effect.