Qhov sib txawv tseem ceeb ntawm lub hauv nruab nrab thiab cov kab mob hauv nruab nrog cev yog cov hauv nruab nrog cev lymphoid ua qhov chaw rau kev tsim thiab loj hlob ntawm lymphocytes, thaum peripheral lymphoid kab mob tswj cov laus naïve lymphocytes thiab pib hloov lub cev tiv thaiv kab mob.
Cov kab mob lymphatic muaj cov kab mob hauv nruab nrog cev uas ua lub luag haujlwm tseem ceeb hauv kev tiv thaiv kab mob thiab kev ua haujlwm ntawm cov kab mob vertebrates. Nws suav nrog lub network ntawm cov hlab ntsha lymphatic, cov qog nqaij hlav hauv nruab nrog cev, thiab cov ntaub so ntswg lymphoid. Cov hlab ntsha no nqa cov kua dej ntshiab hu ua lymph rau lub plawv rau kev ncig. Lymph feem ntau nqa cov lymphocytes. Cov kab mob Lymphoid ua lub luag haujlwm tseem ceeb hauv kev tsim thiab ua kom cov lymphocytes. Cov kab mob no muaj xws li cov qog nqaij hlav, spleen, tonsils, thymus, thiab cov pob txha pob txha. Lub luag haujlwm tseem ceeb ntawm cov kab mob lymphatic suav nrog muab txoj hauv kev rov qab mus rau cov ntshav kom muaj ntau tshaj peb litres thiab tiv thaiv kab mob.
Central Lymphoid Organs yog dab tsi?
Central lymphoid organ tsim cov lymphocytes los ntawm cov hlwb tsis paub tab. Lawv kuj tseem hu ua thawj cov kab mob lymphoid thiab tsim cov pob txha pob txha thiab thymus. Cov kabmob no koom nrog hauv kev tsim khoom thiab kev xaiv clonal ntawm cov ntaub so ntswg lymphocyte.
Daim duab 01: Lymphoid Organs thiab Lymphatic System
pob txha pob txha cuam tshuam rau kev tsim T cell precursors thiab tsim thiab loj hlob ntawm b hlwb. Cov no yog cov hlwb tseem ceeb hauv lub cev tiv thaiv kab mob. B hlwb nkag mus rau hauv lub circulatory system thiab mus rau lub peripheral lymphoid organ nyob rau hauv kev tshawb nrhiav cov kab mob. T hlwb taug kev los ntawm cov pob txha mus rau thymus, qhov chaw uas lawv loj hlob ntxiv. Mature T hlwb koom nrog B hlwb los rhuav tshem cov kab mob. Cov T hlwb ntxiv mus dhau ntawm apoptosis thiab programmed cell tuag. Thymus loj tuaj thaum yug los. Qhov no yog vim muaj cov tshuaj antigen tom qab yug me nyuam. Nws yog nquag siv thaum lub sij hawm neonatal thiab ua ntej tub ntxhais hluas. Lub thymus feem ntau muaj lobules muab faib los ntawm ib lub septum. Kev poob lossis tsis muaj thymus ua rau muaj kev tiv thaiv kab mob hnyav. T hlwb loj hlob los ntawm thymocytes. Txoj kev loj hlob thiab kev xaiv tau tshwm sim hauv thymic cortex ua ntej nkag mus rau medulla.
Peripheral Lymphoid Organs yog dab tsi?
Peripheral lymphoid kab mob tswj cov kab mob loj hlob tsis zoo lymphocytes thiab pib hloov lub cev tiv thaiv kab mob. Lawv kuj tseem hu ua cov kab mob lymphoid thib ob thiab suav nrog cov qog ntshav qab zib thiab tus po. Tus spleen synthesizes cov tshuaj tiv thaiv thiab tshem tawm cov kab mob thiab cov qe ntshav uas muaj cov tshuaj tiv thaiv kab mob los ntawm cov ntshav thiab cov qog ntshav ncig. Lub cev no yog qhov chaw ntawm kev ua haujlwm ntawm mononuclear phagocyte system. Monocytes nyob rau hauv tus po tsiv mus rau cov ntaub so ntswg raug mob, tig mus rau hauv dendritic hlwb thiab macrophages los txhawb cov ntaub so ntswg kho. Qhov tsis muaj tus po ua rau ua ntej tso rau qee yam kab mob.
Cov qog ntshav qab zib muaj cov ntaub so ntswg lymphoid. Lawv nyob hauv lub lymphatic system ntawm lub sijhawm tshwj xeeb. Feem ntau, afferent lymph hlab ntsha coj hauv cov qog ntshav thiab ntws tawm los ntawm cov hlab ntsha lymphatic. Lymph nodes yog tam sim no nyob rau hauv lub zeem muag kawg ntawm caj npab xws li armpits, puab tais, lub caj dab cheeb tsam, hauv siab, thiab plab mog xws li cov hlab ntsha ntawm txoj hnyuv, thaj chaw inguinal, thiab pelvis. Lymph nodes muaj cov lymphoid follicles nyob rau hauv lub cortex. Lawv yog ib tug tuab sau ntawm lymphocytes. Feem ntau T hlwb tsis paub tab nyob hauv lub cortex. Lub cheeb tsam hu ua paracortex ncig lub medulla, thiab nws muaj cov tsis paub tab thiab paub tab. Lymphocytes feem ntau nkag mus rau cov qog ntshav los ntawm qhov siab endothelial venules hauv paracortex. Lymph nodes pab hauv kev xaiv B hlwb, thiab qhov no tshwm sim hauv cov kab mob hauv nruab nrab ntawm cov qog ntshav.
Dab tsi zoo sib xws ntawm Central thiab Peripheral Lymphoid Organs?
- Central thiab peripheral lymphoid organ muaj nyob rau hauv lub lymphatic system.
- Lawv ua lub luag haujlwm tseem ceeb hauv kev tiv thaiv kab mob.
- Ob hom kab mob hauv nruab nrog pab hauv kev loj hlob ntawm lymphocytes.
- Ntxiv mus, ob qho tib si ua lub luag haujlwm tseem ceeb hauv kev ua haujlwm ntawm lub cev tiv thaiv kab mob.
Qhov txawv ntawm Central thiab Peripheral Lymphoid Organs yog dab tsi?
Cov kab mob hauv nruab nrab hauv nruab nrab ua lub luag haujlwm rau kev tsim thiab kev loj hlob ntawm lymphocytes, thaum cov kab mob hauv nruab nrog cev tuav cov lymphocytes paub tab thiab pib hloov lub cev tiv thaiv kab mob. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm cov kab mob hauv nruab nrab thiab peripheral lymphoid. Tsis tas li ntawd, cov kab mob hauv nruab nrab yog hu ua cov kab mob hauv lub cev lymphoid, thaum cov kab mob qog nqaij hlav peripheral hu ua cov kab mob lymphoid thib ob. Ntxiv mus, cov pob txha thiab thymus yog cov kab mob hauv nruab nrab hauv nruab nrab, thaum cov qog ntshav qab zib thiab tus po yog cov piv txwv ntawm peripheral lymphoid organ.
Cov lus hauv qab no qhia txog qhov sib txawv ntawm nruab nrab thiab cov kab mob hauv nruab nrog cev.
Summary – Central vs Peripheral Lymphoid Organs
Cov kab mob lymphatic muaj cov kab mob hauv nruab nrog cev uas ua lub luag haujlwm tseem ceeb hauv kev tiv thaiv kab mob. Central thiab peripheral lymphoid kab mob ua lub luag haujlwm tseem ceeb hauv cov kab ke no. Qhov sib txawv tseem ceeb ntawm cov kab mob hauv nruab nrab thiab cov kab mob peripheral lymphoid yog cov kab mob hauv nruab nrab ntawm cov lymphoid ua lub luag haujlwm rau kev tsim thiab loj hlob ntawm lymphocytes, thaum cov kab mob peripheral lymphoid tswj cov kab mob loj heev naïve lymphocytes thiab pib hloov lub cev tiv thaiv kab mob. Tsis tas li ntawd, cov kab mob hauv nruab nrab lymphoid yog qhov chaw uas cov ntshav thiab lub cev tiv thaiv kab mob tsim tawm thiab T-lymphocyte maturation tshwm sim. Cov kab mob no muaj xws li cov pob txha pob txha thiab thymus. Cov kab mob peripheral lymphoid yog qhov chaw uas qhov sib txawv thiab antigen nyob ntawm kev loj hlob ntawm lymphocytes tshwm sim. Cov kab mob no suav nrog cov qog ntshav qab zib thiab tus po. Yog li, qhov no yog lwm qhov sib txawv ntawm nruab nrab thiab peripheral lymphoid kab mob.
