Qhov sib txawv tseem ceeb ntawm MPV txo qis thiab Oppenauer oxidation yog qhov txo qis MPV cuam tshuam nrog kev hloov pauv ntawm ketone lossis aldehyde rau hauv nws cov cawv sib xws, thaum Oppenauer oxidation cuam tshuam nrog kev hloov pauv ntawm cov cawv thib ob rau ketones.
MPV txo yog hais txog Meerwein-Pondorf-Verley txo. Oppenauer oxidation yog hais txog ib hom oxidation cov tshuaj tiv thaiv npe tom qab Rupert Viktor Oppenauer. Nov yog ob qhov kev tawm tsam tawm tsam.
MPV txo yog dab tsi?
MPV txo yog hais txog Meerwein-Pondorf-Verley txo. Nws yog ib hom kev txo qis cov tshuaj tiv thaiv uas cuam tshuam txog kev txo qis ntawm ketones thiab aldehydes los tsim lawv cov cawv sib xws uas siv txhuas alkoxide catalysis nyob rau hauv lub xub ntiag ntawm cov cawv cawv. Qhov kev txo qis no yog qhov zoo vim nws cov chemoselectivity siab. Peb tuaj yeem siv tus nqi pheej yig, ib puag ncig tus phooj ywg hlau catalyst rau qhov kev txo qis no.
Cov tshuaj tiv thaiv txo qis tau muaj npe tom qab Hans Meerwein, Wolfgang Ponndorf, thiab Albert Verley. Peb tuaj yeem categorize nws raws li cov organic redox cov tshuaj tiv thaiv. Nws cov neeg tsim pom tau tias kev sib xyaw ntawm txhuas ethoxide thiab ethanol tuaj yeem txo aldehydes lossis ketones rau cov cawv sib xws.
Daim duab 01: Kev Sib Tham Zej Zog ntawm MPV txo
Lub tshuab ntawm qhov kev tawm tsam no muaj ob peb kauj ruam:
- Kev sib koom ua ke ntawm carbonyl oxygen atom rau aluminium alkoxide kom muab cov tetra sib koom ua ke aluminium intermediate.
- Tsim cov nruab nrab, hloov cov hydride mus rau carbonyl los ntawm alkoxy ligand ntawm pericyclic mechanism.
- Tsim cov cawv los ntawm kev daws los ntawm kev hloov cov carbonyl txo qis tshiab los ntawm kev tsim cov catalyst
Openauer Oxidation yog dab tsi?
Oppenauer oxidation yog ib hom oxidation cov tshuaj tiv thaiv uas muaj kev hloov pauv ntawm cov cawv thib ob rau ketones los ntawm kev xaiv oxidation. Cov tshuaj tiv thaiv oxidation no muaj npe tom qab Rupert Viktor Oppenauer. Nws yog cov txheej txheem maj mam uas muaj kev xaiv oxidation. Peb kuj tuaj yeem piav qhia nws ua hom tshuaj tiv thaiv kab mob organic.
Daim duab 02: Ib qho piv txwv ntawm Oppenauer Oxidation
Qhov no yog qhov cuam tshuam rau MPV txo. Nyob rau hauv cov tshuaj tiv thaiv no, cov cawv raug oxidation nrog txhuas isopropoxide nyob rau hauv lub xub ntiag ntawm ntau tshaj acetone, uas ua rau cov hloov ntawm qhov sib npaug ntawm cov khoom sab.
Openauer oxidation cov tshuaj tiv thaiv yog xaiv ntawm cov cawv thib ob, thiab nws tsis oxidize lwm pab pawg ua haujlwm, suav nrog amines thiab sulfides. Txawm li cas los xij, peb tuaj yeem oxidize thawj cov cawv hauv cov txheej txheem oxidation no. Tab sis nws yog ua tsis tshua muaj vim yog kev sib tw aldol condensation ntawm aldehyde khoom. Oppenauer oxidation cov tshuaj tiv thaiv yog tseem siv rau oxidation ntawm acid-labile substrates. Tsis tas li ntawd, cov txheej txheem no tau hloov pauv loj heev los ntawm txoj kev oxidation nyob ntawm cov chromates lossis dimethyl sulfoxide vim nws siv cov tshuaj nruab nrab thiab tsis muaj tshuaj lom.
Qhov txawv ntawm MPV txo thiab Oppenauer Oxidation yog dab tsi?
MPV txo thiab Oppenauer oxidation yog qhov tseem ceeb ntawm cov tshuaj lom neeg cov tshuaj tiv thaiv. Qhov sib txawv tseem ceeb ntawm MPV txo qis thiab Oppenauer oxidation yog qhov kev txo qis MPV suav nrog kev hloov pauv ntawm ketone lossis aldehyde rau hauv nws cov cawv sib xws, thaum Oppenauer oxidation cuam tshuam nrog kev hloov pauv ntawm cov cawv thib ob rau ketones.
Cov ntawv qhia hauv qab no nthuav tawm qhov sib txawv ntawm MPV txo qis thiab Oppenauer oxidation hauv daim ntawv tabular rau ib sab ntawm kev sib piv.
Summary – MPV Reduction vs Oppenauer Oxidation
MPV txo thiab Oppenauer oxidation yog ob qho kev tawm tsam. Qhov sib txawv tseem ceeb ntawm MPV txo qis thiab Oppenauer oxidation yog qhov txo qis MPV suav nrog kev hloov pauv ntawm ketone lossis aldehyde rau hauv nws cov cawv sib xws, qhov Oppenauer oxidation cuam tshuam nrog kev hloov pauv ntawm cov cawv thib ob rau ketones.
