Qhov sib txawv tseem ceeb ntawm serine thiab threonine yog tias serine yog ib qho tsis tseem ceeb amino acid uas muaj α amino pawg, pawg carboxyl, thiab ib sab saw uas muaj pawg hydroxymethyl, thaum threonine yog ib qho tseem ceeb amino acid. uas muaj ib pawg α amino, pawg carboxyl, thiab ib sab saw uas muaj cov pab pawg hydroxyl.
Amino acids yog cov ua ntej ua cov protein ntau. Lawv yog cov organic tebchaw uas muaj cov amino (NH3+) carboxyl (COO–) pawg ua haujlwm. Muaj plaub lub ntsiab amino acids chav kawm raws li polarity. Lawv yog cov amino acids uas tsis yog-polar side chains (tryptophan), amino acids nrog uncharged polar side chains (serine, threonine), amino acids nrog polar negatively them sab chains (aspartic acid), thiab amino acids nrog polar positive charged side chains (lysine). Serine thiab threonine yog ob qho amino acids uas tsis tau them tus polar side chains.
Serine yog dab tsi?
Serine yog ib qho amino acid uas muaj α-amino pawg, pawg carboxyl, thiab ib sab saw uas muaj pawg hydroxymethyl. Nws yog ib qho amino acid uas tsis muaj kev sib txuas ntawm cov kab nruab nrab sab qaum teb. Yog li ntawd, nws yog cais raws li ib tug polar amino acid. Nws tuaj yeem ua ke nyob rau hauv tib neeg lub cev nyob rau hauv ib txwm physiological mob. Qhov no ua rau nws tsis tseem ceeb amino acid. Nws feem ntau yog encoded los ntawm codons UCU, UCC, UCA, UCG, AGU, thiab AGC nyob rau hauv genetic code. Cov organic compound no yog ib qho ntawm cov proteinogenic amino acids tshwm sim. Nws yog thawj zaug tau los ntawm silk protein nyob rau hauv 1865 los ntawm Emil Cramer. Cov khoom noj uas nplua nuj nyob hauv L stereoisomer ntawm serine yog qe, yaj, daim siab, edamame, taum paj, nqaij npuas sardines, seaweed, thiab lwm yam. Industrially, serine tuaj yeem tsim los ntawm glycine thiab methanol catalyzed los ntawm enzyme hydroxymethyltransferase.
Daim duab 01: Serine
Serine muaj ntau yam haujlwm lom neeg. Nws koom nrog hauv biosynthesis ntawm purines thiab pyrimidines. Serine kuj tseem ua lub luag haujlwm tseem ceeb hauv kev ua haujlwm catalytic ntawm ntau cov enzymes xws li chymotrypsin thiab trypsin. Tsis tas li ntawd, D-serine yog lub teeb liab molecule hauv lub hlwb. Serine deficiency ua rau muaj kev cuam tshuam xws li cov tsos mob ntawm lub paj hlwb loj xws li congenital microcephaly, psychomotor retardation hnyav. Tsis muaj serine tuaj yeem ua rau qaug dab peg.
Threonine yog dab tsi?
Threonine yog ib qho amino acid uas muaj α-amino pawg, pawg carboxyl, thiab ib sab saw uas muaj pawg hydroxyl. Nws kuj yog ib qho amino acid nrog ib qho kev tsis sib haum xeeb ntawm cov saw hlau. Nws yog ib qho tseem ceeb amino acid rau tib neeg txij li thaum nws tsis tuaj yeem tsim nyob rau hauv tib neeg lub cev nyob rau hauv ib txwm physiological tej yam kev mob. Nws yuav tsum tau muab los ntawm kev noj haus. Threonine yog tsim los ntawm aspartate hauv cov kab mob E.coli. Nws yog encoded los ntawm codons ACU, ACC, ACA, thiab ACG nyob rau hauv cov caj ces code. Cov amino acid no tau pom thawj zaug los ntawm William Cumming Rose thiab Curtis Mayer hauv xyoo 1936. Cov neeg laus xav tau threonine txog 20 mg / kg lub cev hnyav ib hnub. Cov khoom noj uas muaj threonine muaj xws li tsev cheese, nqaij qaib, ntses, nqaij, lentils, dub vaub kib taum, thiab noob hnav.
Daim duab 02: Threonine
Threonine ua tiav cov haujlwm lom neeg sib txawv. Nws yog ib qho tseem ceeb ntawm lub plab hnyuv mucin. Threonine kuj yog ib qho khoom noj khoom haus modulator ntawm txoj hnyuv tiv thaiv kab mob los ntawm kev sib txuas lus sib txuas. Tsis tas li ntawd, threonine dehydratase deficiency tuaj yeem ua rau tsis yog-ketotic hyperglycinaemia. Threonine tsis muaj peev xwm kuj tuaj yeem ua rau kev ua haujlwm ntawm lub paj hlwb thiab lameness.
Dab tsi zoo sib xws ntawm Serine thiab Threonine?
- Serine thiab threonine yog ob lub amino acids uas tsis tau them tus ncej qaum teb.
- ob leeg yog proteinogenic amino acids.
- Lawv tsim cov qauv me me xws li ST tig, ST motif, thiab ST staples los ntawm kev sib tham.
- Kev tsis txaus ntawm ob qho tib si ua rau mob hlwb.
Qhov txawv ntawm Serine thiab Threonine yog dab tsi?
Serine yog ib qho tsis tseem ceeb amino acid tsim los ntawm ib pawg α-amino, pawg carboxyl thiab ib sab saw uas muaj cov pab pawg hydroxymethyl, thaum threonine yog ib qho tseem ceeb amino acid tsim los ntawm α-amino pawg, a pawg carboxyl thiab ib sab saw muaj xws li hydroxyl pawg. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm serine thiab threonine. Tsis tas li ntawd, serine yog encoded los ntawm codons UCU, UCC, UCA, UCG, AGU thiab AGC nyob rau hauv cov noob caj noob ces, thaum threonine yog encoded los ntawm ACU, ACC, ACA thiab ACG nyob rau hauv cov noob caj noob ces code.
Cov hauv qab no infographic teev qhov sib txawv ntawm serine thiab threonine hauv daim ntawv tabular rau ib sab ntawm kev sib piv.
Summary – Serine vs Threonine
Serine thiab threonine yog ob qho proteinogenic amino acids. Lawv kuj yog ob cov amino acids uas tsis muaj cov kab hluav taws xob sab qaum teb. Serine yog ib qho tsis tseem ceeb amino acid uas tsim los ntawm ib pawg α-amino, pawg carboxyl thiab ib sab saw uas muaj cov pab pawg hydroxymethyl, thaum threonine yog ib qho tseem ceeb amino acid tsim los ntawm ib pawg α-amino, pawg carboxyl thiab ib sab saw. muaj ib pawg hydroxyl. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm serine thiab threonine.
