Qhov sib txawv tseem ceeb ntawm methotrexate thiab methotrexate sodium yog tias methotrexate yog tus kws kho mob, hos methotrexate sodium yog sodium ntsev ntawm methotrexate.
Methotrexate yog cov tshuaj tiv thaiv kab mob uas muaj cov chaw carbonyl, pawg amine thiab cov nplhaib uas muaj ntxhiab hauv nws cov qauv tshuaj. Cov ntsev ntsev ntawm cov tshuaj no muaj ob lub sodium cations nyob rau hauv qhov chaw ntawm ob lub hydrogen atoms nyob rau hauv ob lub chaw carbonyl ntawm methotrexate compound; Yog li, peb tuaj yeem hu nws ua methotrexate disodium lossis tsuas yog methotrexate sodium.
Methotrexate yog dab tsi?
Methotrexate yog tus kws khomob khomob thiab kev tiv thaiv kabmob tiv thaiv kabmob. Cov tshuaj no tseem hu ua amethopterin. Peb tuaj yeem siv cov tshuaj no los kho mob qog noj ntshav, kab mob autoimmune, cev xeeb tub ectopic, thiab kev rho menyuam tawm. Methotrexate tuaj yeem kho cov qog nqaij hlav xws li mob qog noj ntshav mis, leukemia, mob ntsws cancer, lymphoma, thiab kab mob gestational trophoblastic.
Txawm li cas los xij, tuaj yeem muaj qee yam kev mob tshwm sim los ntawm cov tshuaj no, suav nrog xeev siab, nkees, ua npaws, muaj kev pheej hmoo kis mob, thiab cov qe ntshav dawb tsawg. Qee qhov kev mob tshwm sim loj ntawm kev siv methotrexate muaj xws li kab mob siab, kab mob ntsws, lymphoma, thiab ua pob tawv nqaij hnyav. Tsis tas li ntawd, cov tshuaj no tsis muaj kev nyab xeeb rau kev siv thaum pub niam mis, raws li qee qhov kev tshawb fawb tshawb fawb. Cov tshuaj ua los ntawm kev thaiv lub cev siv cov folic acid.
Daim duab 01: Cov qauv tshuaj ntawm Methotrexate
Thaum xav txog txoj hauv kev ntawm kev tswj hwm rau cov tshuaj methotrexate, nws tuaj yeem muab los ntawm qhov ncauj lossis txhaj tshuaj. Kev txhaj tshuaj peb tuaj yeem siv tau suav nrog intramuscular, intravenous, subcutaneous, lossis intrathecal txhaj. Ntxiv mus, peb yuav tsum noj cov tshuaj no txhua lub lim tiam, tsis yog txhua hnub. Qhov ntawd yog txhawm rau txo cov tshuaj toxicity ntawm cov tshuaj. Yog tias peb noj cov tshuaj methotrexate ntau, nws tuaj yeem ua rau muaj qee yam tsis zoo xws li hepatotoxicity (los yog daim siab puas), ulcerative stomatitis, thiab leukopenia.
Methotrexate Sodium yog dab tsi?
Methotrexate sodium yog sodium ntsev ntawm methotrexate. Nws yog antimetabolite nrog antineoplastic thiab immunomodulating zog. Cov tshuaj no nyiam khi rau cov enzyme dihydrofolate reductase thiab inhibits cov enzymes. Nws ua rau inhibition ntawm purine nucleotide thiab thymidylate synthesis, thiab thaum kawg, nws tuaj yeem inhibit DNA thiab RNA syntheses. Cov tshuaj formula rau cov khoom no yog C20H20N8Na2O5. Cov tshuaj no muaj ob lub sodium cations txuam nrog methotrexate compound. Ob lub sodium cations hloov ob lub hydrogen atoms hauv cov chaw carbonyl ntawm methotrexate compound.
Qhov txawv ntawm Methotrexate thiab Methotrexate Sodium yog dab tsi?
Cov ntsev ntsev ntawm methotrexate compound muaj ob lub sodium cations nyob rau hauv qhov chaw ntawm ob hydrogen atoms nyob rau hauv ob lub chaw carbonyl ntawm cov methotrexate compound; Yog li, peb tuaj yeem hu nws ua methotrexate disodium lossis tsuas yog methotrexate sodium. Qhov sib txawv tseem ceeb ntawm methotrexate thiab methotrexate sodium yog tias methotrexate yog tus neeg sawv cev kho mob, hos methotrexate sodium yog sodium ntsev ntawm methotrexate.
Ntxiv mus, lwm qhov sib txawv ntawm methotrexate thiab methotrexate sodium yog tias methotrexate yog ib qho nruab nrab organic compound thaum methotrexate sodium yog ib qho ionic compound uas muaj ob lub sodium cations. Ntxiv rau qhov sib txawv no, methotrexate ua haujlwm los ntawm kev thaiv lub cev siv cov tshuaj folic acid, thaum methotrexate sodium khi rau enzyme dihydrofolate reductase thiab inhibits cov enzyme.
Hauv qab infographic tabulates qhov sib txawv ntawm methotrexate thiab methotrexate sodium.
Summary – Methotrexate vs Methotrexate Sodium
Methotrexate yog ib yam tshuaj uas peb siv tau los kho mob qog noj ntshav. Qhov sib txawv tseem ceeb ntawm methotrexate thiab methotrexate sodium yog tias methotrexate yog tus kws kho mob, thaum methotrexate sodium yog sodium ntsev ntawm methotrexate. Methotrexate sodium yog antimetabolite nrog antineoplastic thiab immunomodulating zog. Cov tshuaj formula rau cov ntsev disodium no yog C20H20N8Na2O5.
