Qhov sib txawv tseem ceeb ntawm filgrastim thiab pegfilgrastim yog tias filgrastim yog cov tshuaj siv los kho neutropenia, uas yog ib qho mob uas tsis tshua muaj neutrophil suav hauv cov ntshav, thaum pegfilgrastim yog ib daim ntawv pegylated ntawm tib neeg cov colony-stimulating yam uas yog. neeg tsim
Filgrastim thiab pegfilgrastim yog ob hom tshuaj. Filgrastim yog ib qho tshuaj hluavtaws uas zoo ib yam li cov khoom tsim tawm los ntawm kev ua kom muaj zog. Nws tuaj raws li kev txhaj tshuaj los kho cov neeg mob uas muaj neutropenia, uas yog ib qho mob ntawm cov qe ntshav dawb. Tsis tas li ntawd, filgrastim txhawb kev tsim cov qe ntshav dawb tshiab nyob rau hauv cov pob txha pob txha, txo txoj kev kis kab mob hauv cov neeg mob qog noj ntshav thiab tau txais kev kho mob. Pegfilgrastim yog ib qho analog ntawm filgrastim uas yog hu ua PEGylated daim ntawv ntawm recombinant human granulocyte colony-stimulating factor. Nws kuj yog siv los kho cov ntshav dawb tsawg hauv cov ntshav.
Filgrastim yog dab tsi?
Filgrastim yog cov tshuaj siv los kho cov tshuaj neutrophil qis. Nws yog ib hom biologic teb modifier tsim siv recombinant DNA technology. Nws yog cov protein uas muaj qhov hnyav molecular ntawm 18,800 d altons. Tsis tas li ntawd, nws yog ib hom kab mob-stimulating yam thiab ib tug hematopoietic neeg sawv cev. Muaj ntau lub npe lag luam siv los xa mus rau cov tshuaj no. Lawv yog Neupogen, Granix, Zarxio thiab Granulocyte - colony-stimulating factor. Qhov tseeb, filgrastim yog cov tshuaj txhawb nqa uas txhawb kev tsim cov granulocytes hauv cov neeg mob uas muaj cov qe ntshav dawb tsawg. Filgrastim tsis tsuas yog pab tsim cov neutrophils, tab sis nws kuj pab kom loj hlob thiab qhib neutrophils. Tsis tas li ntawd, nws txhawb kev tso tawm ntawm neutrophils los ntawm cov pob txha pob txha. Tshwj xeeb tshaj yog nyob rau hauv cov neeg mob tau txais kev kho mob, filgrastim accelerates tus rov qab ntawm neutrophils los ntawm kev txo cov theem ntawm neutropenic.
Daim duab 01: Filgrastim
Filgrastim tuaj yeem txhaj lossis nkag mus rau hauv cov leeg. Feem ntau, cov tshuaj no yuav tsum tau khaws cia hauv lub tub yees thiab yuav tsum tau muab tshem tawm ntawm nws 30 feeb ua ntej txhaj tshuaj. Qhov tseem ceeb tshaj plaws, nws yuav tsum tsis txhob shaken thiab khaws cia nyob rau hauv tshav ntuj. Tus nqi ntawm cov tshuaj filgrastim txawv ntawm cov tib neeg raws li qhov siab, qhov hnyav, kev noj qab haus huv lossis lwm yam teeb meem kev noj qab haus huv, hom mob qog noj ntshav lossis mob tau kho.
Pegfilgrastim yog dab tsi?
Pegfilgrastim yog PEGylated lossis pegylated daim ntawv ntawm tib neeg granulocyte colony-stimulating yam. Nws yog ib qho analog ntawm filgrastim. Lub npe lag luam ntawm pegfilgrastim yog Neulasta. Zoo ib yam li filgrastim, pegfilgrastim kuj yog ib qho tshuaj uas tib neeg tsim siv los kho neutropenia lossis qhov mob qis thaum cov qe ntshav hauv cov ntshav. Pegfilgrastim txhawb kev tsim cov neutrophils hauv cov neeg mob uas tau txais kev kho mob. Los ntawm kev ua kom cov qe ntshav dawb ntau lawm, pegfilgrastim txo txoj kev kis kab mob. Qhov tseem ceeb tshaj plaws, pegfilgrastim txhawb nqa cov pob txha pob txha los tsim cov qe ntshav dawb ntau dua los tiv thaiv kab mob. Zoo ib yam li filgrastim, pegfilgrastim kuj tau txhaj rau hauv qab ntawm daim tawv nqaij.
Dab tsi yog qhov zoo sib xws ntawm Filgrastim thiab Pegfilgrastim?
- Filgrastim thiab pegfilgrastim yog ob yam tshuaj uas yog cov proteins.
- Pegfilgrastim yog ib qho analog ntawm filgrastim.
- Qhov tseeb, nws yog daim ntawv ua yeeb yam ntev dua.
- Ob lub tshuaj yog siv los kho neutropenia.
- Ob yam tshuaj yog tshuaj hluavtaws.
- Lawv ua haujlwm raws li kev hloov pauv biologic.
- Ob yam tshuaj no tsuas yog txhawb kev tsim cov qe ntshav dawb thiab txo qis kev kis kab mob hauv cov neeg mob uas tau txais tshuaj kho mob.
- Yog tias koj muaj kev fab tshuaj, koj yuav tsum tsis txhob noj filgrastim lossis pegfilgrastim.
- Ob qho tib si filgrastim thiab pegfilgrastim tau muab ua kev txhaj tshuaj.
Qhov txawv ntawm Filgrastim thiab Pegfilgrastim yog dab tsi?
Filgrastim yog ib qho tshuaj siv los kho tus mob hu ua neutropenia, uas ua rau cov qe ntshav dawb hauv cov ntshav qis vim qee cov qog nqaij hlav thiab tshuaj kho mob. Ntawm qhov tod tes, pegfilgrastim yog ib daim ntawv pegylated ntawm tib neeg cov colony-stimulating yam uas yog tib neeg tsim. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm filgrastim thiab pegfilgrastim. Neupogen, Granix, Zarxio thiab Granulocyte - colony-stimulating factor yog cov npe lag luam ntawm filgrastim, thaum Neulasta yog lub npe lag luam ntawm pegfilgrastim.
Summary – Filgrastim vs Pegfilgrastim
Filgrastim thiab pegfilgrastim yog ob yam tshuaj uas yog cov protein. Lawv yog cov tshuaj hluavtaws (man-made). Ob hom tshuaj yog siv los txhawb kev tsim cov qe ntshav dawb hauv cov neeg mob uas tau txais kev kho mob. Ob qho tshuaj txhawb cov pob txha pob txha los tsim cov qe ntshav dawb ntau dua los tiv thaiv kab mob. Pegfilgrastim yog ib daim ntawv pegylated ntawm tib neeg cov colony-stimulating yam. Nws yog ib hom kev ua yeeb yam ntev ntawm filgrastim. Ob qho tshuaj yog muab raws li kev txhaj tshuaj feem ntau hauv qab ntawm daim tawv nqaij. Yog li, qhov no qhia txog qhov sib txawv ntawm filgrastim thiab pegfilgrastim.
