Qhov sib txawv tseem ceeb ntawm lamellipodia thiab filopodia yog tias lamellipodia yog cytoskeletal actin projections tam sim no nyob rau hauv lub xov tooj ntawm tes ntawm lub hlwb thaum filopodia yog nyias cytoplasmic protrusions uas txuas los ntawm cov thawj ntug ntawm lub cell cell.
Lamellipodia thiab filopodia yog ob lub xovtooj txuas ntxiv uas feem ntau siv hauv xovtooj ntawm tes thiab tsiv teb tsaws. Cov qauv no paub txog cov xwm txheej extracellular thiab locomote feem. Yog li ntawd, lawv yog cov qauv tseem ceeb rau kev txav ntawm tes. Tsis tas li ntawd, microspikes xa mus rau cov lamellipodia thiab filopodia, thiab tsim cov actin filaments. Ob lub qauv muaj nyob rau ntawm ntug ntawm lub cell tsiv teb tsaws.
Lamellipodia yog dab tsi?
Lamellipodia yog cytoskeleton protrusions nyob rau hauv lub tiaj tus ribbon-puab thiab tam sim no nyob rau hauv periphery ntawm ib tug migrating cell. Cov protrusions yog enriched nrog ib tug branched network ntawm bi-dimensional dendric array ntawm actin filaments. Hauv lwm lo lus, lamellipodium muaj ob-seem actin mesh uas txhawb nqa tag nrho cov qauv ntawm tes thoob plaws hauv lub substrate. Yog li ntawd, lawv tseem ceeb heev rau kev tsiv teb tsaws ntawm tes.
Daim duab 01: Lamellipodium thiab Filopodium
Lamellipodia ua haujlwm zoo li lub cev muaj zog thiab rub lub hlwb mus rau pem hauv ntej thaum tsiv ntawm tes. Yog li ntawd, nws yog ib tug yam ntxwv feature tam sim no nyob rau hauv pem hauv ntej ntug ntawm motile cell. Lamellipodia feem ntau muaj nyob rau hauv keratinocytes ntawm cov ntses thiab qav, uas tso cai rau lawv txav mus los ntawm epithelial nto ntawm speeds ntawm 10-20 μm / min. Txawm hais tias lamellipodia cais tawm ntawm lub cell, lawv tseem muaj peev xwm txav mus los ntawm nws tus kheej, ywj pheej.
Filopodia yog dab tsi?
Filopodia yog membranous cytoplasmic protrusions tam sim no nyob rau hauv ib lub xovtooj los soj ntsuam qhov chaw nyob sab nraud. Yog li ntawd, lawv ua raws li antennas. Filopodia yog nyias protrusions feem ntau tam sim no nyob rau hauv dawb kawg ntawm migratory ntaub so ntswg embedded nyob rau hauv los yog ncua ntawm lub lamellipodium. Cov protrusions no feem ntau tshwm sim nyob rau hauv kev loj hlob cones ntawm neurons, protruding kawg ntawm migratory hlwb, nplooj ntawv epithelial thiab nyob rau hauv ib tug neeg lub hlwb xws li fibroblasts.
Daim duab 02: Filopodia
Filopodia muaj actin filaments teem nyob rau hauv parallel bundles nrog ib txoj kab uas hla ntawm 60-200 nm. Yog li, txhua filopodium muaj 10-30 actin filaments. Tsis tas li ntawd, khi cov proteins xws li fascin thiab fimbrin tuav cov actin filaments ua ke. Cov kev taw qhia ntawm cov filaments no tshwm sim kom cov barbed xaus yog coj mus rau lub extending membrane. Lub distal kawg ntawm txhua filopodium muaj cell nto receptors. Cov receptors no ua raws li cov sensors los soj ntsuam qhov chaw sab nraud. Kev sib dhos ntawm filopodia muaj peb theem pib: filament nucleation, sustained barbed kawg elongation, thiab filament bundling.
Dab tsi zoo sib xws ntawm Lamellipodia thiab Filopodia?
- Lamellipodia thiab filopodia yog tsim los ntawm actin filaments.
- Tsis tas li ntawd, ob qho tib si muaj nyob rau ntawm ntug kev ntawm cov hlwb tsiv teb tsaws.
- Ob leeg lamellipodia thiab filopodia paub qhov chaw nyob sab nraud thiab pab hauv kev tsiv teb tsaws ntawm tes.
Qhov txawv ntawm Lamellipodia thiab Filopodia yog dab tsi?
Lamellipodia yog cytoskeletal protein actin projections uas tshwm sim ntawm ntug ntawm cov hlwb tsiv teb tsaws. Txawm li cas los xij, filopodia yog cov cytoplasmic cytoplasmic uas txuas mus dhau ntawm cov ntug ntawm lamellipodia hauv cov hlwb tsiv teb tsaws. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm lamellipodia thiab filopodia. Tsis tas li ntawd, lamellipodia tshwj xeeb heev rau kev tsiv teb tsaws ntawm tes thaum filopodia tshwj xeeb rau kev hnov qhov chaw sab nraud. Li no, peb tuaj yeem xav txog qhov no kuj yog qhov sib txawv ntawm lamellipodia thiab filopodia.
Cov hauv qab no qhia txog qhov sib txawv ntawm lamellipodia thiab filopodia.
Summary – Lamellipodia vs Filopodia
Lamellipodia thiab filopodia yog ob qhov txuas ntxiv tam sim no hauv cov npoo ntawm cov hlwb tsiv teb tsaws. Ob leeg muaj actin filaments. Txawm li cas los xij, lamellipodium yog qhov txuas ntxiv cytoskeletal tab sis, filopodium yog qhov txuas ntxiv cytoplasmic. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm lamellipodia thiab filopodia. Ntxiv mus, txawm tias ob qho tib si txuas ntxiv pab hauv kev tsiv teb tsaws ntawm tes, filopodia tuaj yeem soj ntsuam qhov chaw nyob sab nraud. Txawm li cas los xij, lamellipodia tshwj xeeb heev rau kev tsiv teb tsaws ntawm tes. Hauv cov ntses thiab qav, cov lamellipodia muaj nyob hauv cov keratinocytes. Yog li, qhov no yog cov ntsiab lus ntawm qhov sib txawv ntawm lamellipodia thiab filopodia.
