Qhov sib txawv tseem ceeb ntawm enzyme activator thiab enzyme inhibitor yog tias cov enzyme activator tuaj yeem ua rau muaj kev ua haujlwm ntawm ib qho enzyme thaum lub enzyme inhibitor tuaj yeem txo qhov kev ua ntawm enzyme.
Enzymes yog cov proteins, thiab lawv muaj cov amino acids thiab yog cov khoom siv roj ntsha. Ib qho catalyst yog ib qho kev sib xyaw uas tuaj yeem txo cov tshuaj tiv thaiv ntawm cov tshuaj tiv thaiv. Ob hom kev sib txuas tuaj yeem cuam tshuam rau kev ua haujlwm ntawm enzymes; Lawv yog cov activators thiab inhibitors. Cia peb tham ntxiv txog cov ntsiab lus no.
Enzyme Activator yog dab tsi?
Enzyme activators yog hom tshuaj lom neeg uas tuaj yeem khi nrog cov enzyme kom nce nws cov haujlwm. Yog li, lawv tuaj yeem cuam tshuam ncaj qha rau kev ua haujlwm ntawm enzyme. Lawv ua qhov sib txawv uas cov enzyme inhibitors ua haujlwm. Feem ntau ntawm lub sijhawm, lawv ua los ntawm kev khi rau qee thaj chaw, tsis yog qhov chaw nquag ntawm cov enzyme. Cov no yog qhov peb hu ua "cov chaw allosteric" ntawm cov enzyme.
Qee lub sij hawm, lub substrate los yog lub reactant nws tus kheej ua tus activator thaum no reactant khi nrog ib tug active site ntawm lub enzyme. Yog li ntawd, nws muaj peev xwm nce nyob rau hauv lub enzyme affinity rau substrates thiab activates lwm active sites thiab. Qee qhov piv txwv tseem ceeb ntawm cov molecules muaj xws li hexokinase-I thiab glucokinase.
Enzyme Inhibitor yog dab tsi?
Enzyme inhibitors yog hom tshuaj uas tuaj yeem khi nrog cov enzyme kom txo nws txoj haujlwm. Yog li, lawv tuaj yeem cuam tshuam ncaj qha rau kev ua haujlwm ntawm enzyme. Lawv ua qhov sib txawv uas cov enzyme activators ua haujlwm. Ib yam li ntawd, feem ntau ntawm cov inhibitors thaiv qhov chaw nquag ntawm cov enzyme. Yog li lawv tuaj yeem txo qhov kev ua haujlwm ntawm enzyme.
Daim duab 01: Kev khi ntawm Inhibitors thiab Activators rau hauv Allosteric site ntawm ib qho Enzyme
Qee zaum, lawv khi rau qhov chaw allosteric thiab. Kev khi ntawm cov molecule no tuaj yeem thim rov qab lossis rov qab tsis tau. Nyob rau hauv reversible binding, inhibitors raug tshem tawm los ntawm lub enzyme tom qab thaiv kev khi ntawm lub substrate. Ntawm qhov tsis sib xws, hauv irreversible binding, inhibitors tuaj yeem hloov cov duab ntawm qhov chaw nquag irreversibly. Yog li ntawd, tsis muaj substrates ntxiv yuav khi nrog lub active site ntawm lub enzyme. Qee qhov piv txwv xws li tshuaj, ribonuclease inhibitor, thiab lwm yam.
Qhov txawv ntawm Enzyme Activator thiab Enzyme Inhibitor yog dab tsi?
Enzyme activators yog hom tshuaj lom neeg uas tuaj yeem khi nrog cov enzyme kom nce nws cov haujlwm. Yog li, lawv tuaj yeem cuam tshuam kev ua haujlwm ntawm enzyme. Qee qhov piv txwv ntawm cov enzyme activators suav nrog hexokinase-I thiab glucokinase. Enzyme inhibitors yog hom tshuaj uas tuaj yeem khi nrog cov enzyme kom txo nws txoj haujlwm. Yog li ntawd, lawv tuaj yeem cuam tshuam rau kev ua haujlwm ntawm enzyme hauv kev txo qis. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm enzyme activator thiab enzyme inhibitor. Qee qhov piv txwv ntawm enzyme inhibitors suav nrog tshuaj, ribonuclease inhibitor, thiab lwm yam.
Summary – Enzyme Activator vs Enzyme Inhibitor
Cov activators thiab inhibitors yog ob lub molecules uas tuaj yeem cuam tshuam rau kev ua haujlwm ntawm enzyme. Qhov sib txawv ntawm enzyme activator thiab enzyme inhibitor yog tias cov enzyme activators tuaj yeem ua rau kom muaj kev ua haujlwm ntawm ib qho enzyme thaum cov enzyme inhibitors tuaj yeem txo cov haujlwm ntawm cov enzyme.
