Qhov sib txawv tseem ceeb ntawm Paget's Disease thiab Eczema yog tias Paget's kab mob yog ib qho teeb meem ntawm kev kho pob txha, thiab eczema yog ib qho mob ntawm daim tawv nqaij uas muaj cov kab mob vesicular nrog rau qib sib txawv ntawm exudates thiab scaling.
Paget tus kab mob tshwm sim vim muaj kev hloov pauv hauv qee cov noob xws li cov khoom siv nuclear kappa B, sequestosome p62, thiab osteoprotegerin. Ntawm qhov tod tes, eczema tshwm sim raws li qhov tshwm sim ntawm cov tshuaj tiv thaiv hypersensitivity mounted tawm tsam sib txawv allergens. Qhov txawv ntawm pathogenesis yog qhov sib txawv ntawm ob kab mob.
Paget's Disease yog dab tsi?
Paget's disease yog ib qho teeb meem ntawm kev kho pob txha. Thaum pib, muaj kev nce hauv cov pob txha resorption uas yog ua raws li kev them nyiaj ntxiv rau hauv cov pob txha tshiab. Qhov tshwm sim yog tsim ntawm cov pob txha pob txha txawv txav.
Cov neeg siab dua 40 xyoo yog cov neeg raug mob ib txwm muaj, thiab muaj poj niam ua ntej. Ib qho kev nthuav dav ntau dua tau pom nyob hauv thaj av European. Kev koom tes ntawm ntau cov noob suav nrog cov khoom siv hluav taws xob nuclear kappa B, sequestosome p62, thiab osteoprotegerin tau cuam tshuam rau hauv cov kab mob ntawm Paget's disease.
Tshuaj Kho Mob
- mob pob txha (tsuas yog nyob rau hauv tus txha nraub qaum lossis lub plab)
- mob pob qij txha
- pob txha deformities
- Neurological deficits vim yog compression ntawm cranial qab haus huv mas II, V, VII thiab VIII. Spinal stenosis thiab hydrocephalus tuaj yeem tshwm sim.
- High output cardiac failure
- YPathological fractures
- Qee zaus osteogenic sarcomas tuaj yeem tshwm sim
Daim duab 01: X-ray scan Paget's Disease in Vertebra
Kev tshawb nrhiav
- X-ray - lytic lesions tuaj yeem pom nyob rau hauv thawj theem ua raws li theem sib xyaw thiab nyob rau theem siab tshaj plaws, kev tsim cov pob txha txawv txav tuaj yeem txheeb xyuas.
- Isotope pob txha scan tuaj yeem siv los txheeb xyuas qhov cuam tshuam ntawm pob txha
- Serum alkaline phosphatase nce ntxiv nrog rau qib urinary hydroxyproline
Kev tswj hwm
Bisphosphonates yog cov tshuaj xaiv hauv kev tswj hwm. Cov chav kawm tshuaj yog muab ncua tsis tu ncua nyob ntawm qib alkaline phosphatase thiab qib urinary hydroxyproline. Cov neeg mob asymptomatic uas muaj cov kab mob uas pom nyob rau hauv cov duab hluav taws xob yog tias muaj peev xwm ua rau muaj teeb meem xws li pob txha ntawm qhov hnyav-cov pob txha ntev.
Eczema yog dab tsi?
Eczema yog ib qho mob ntawm daim tawv nqaij uas ua los ntawm cov kab mob vesicular nrog rau qib sib txawv ntawm exudates thiab scaling. Vesicles tsim raws li qhov tshwm sim ntawm edema nyob nruab nrab ntawm cov kab mob epidermal. Muaj ntau hom eczema. Atopic dermatitis yog ib qho ntawm lawv. Lwm hom kab mob eczema suav nrog, Tus kab mob dermatitis yog dermatitis precipitated los ntawm exogenous agents, thiab feem ntau nws yog tshuaj. Nickel rhiab heev yog qhov kev tsis haum rau kev sib cuag, cuam tshuam rau 10% ntawm cov poj niam thiab 1% ntawm cov txiv neej.
Etiopathogenesis
Irritants dua li allergens feem ntau ua rau mob dermatitis. Txawm li cas los xij, cov tsos mob ntawm ob qho tib si zoo li zoo sib xws. Allergic contact dermatitis yog tshwm sim los ntawm immunologically los ntawm hom Ⅳ hypersensitivity tshua. Cov txheej txheem tag nrho uas irritants ua rau dermatitis sib txawv, tab sis qhov ncaj qha tsis zoo rau ntawm daim tawv nqaij txoj kev ua haujlwm yog qhov feem ntau pom mechanism.
Cov tshuaj tiv thaiv tseem ceeb tshaj plaws cuam tshuam nrog kev sib cuag dermatitis yog;
- Abrasives ex: frictional irritancy
- Dej thiab lwm yam kua dej
- Tshuaj ex: acids thiab alkalis
Cov txiaj ntsig ntawm feem ntau ntawm cov khaus khaus yog mob ntev, tab sis muaj zog khaus ua rau necrosis ntawm cov kab mob epidermal tuaj yeem tsim cov tshuaj tiv thaiv tsis pub dhau ob peb teev. Cov kab mob dermatitis tuaj yeem tshwm sim los ntawm kev rov ua dua thiab sib xyaw ua ke rau cov dej abrasives thiab tshuaj lom neeg ntau lub hlis lossis xyoo. Qhov no feem ntau tshwm sim hauv tes. Kev cuam tshuam ntawm cov neeg uas muaj keeb kwm ntawm atopic eczema rau irritants, kom muaj kev sib cuag dermatitis yog siab.
Kev nthuav qhia kho mob
Cov kab mob dermatitis tuaj yeem cuam tshuam rau txhua qhov ntawm lub cev. Thaum dermatitis tshwm sim ntawm ib qhov chaw, qhov ntawd qhia tau tias muaj kev sib cuag nrog qee yam khoom. Thaum tus neeg mob muaj keeb kwm ntawm Nickel allergy tshwm sim nrog eczema ntawm lub dab teg, nws qhia txog kev tsis haum rau lub watch pluaj buckle. Nws yog ib qho yooj yim los sau qhov ua tau los ntawm kev paub tus neeg mob txoj haujlwm, kev nyiam ua, yav dhau los keeb kwm thiab kev siv tshuaj pleev ib ce lossis tshuaj. Qhov chaw ib puag ncig ntawm qee cov tshuaj tsis haum yog muab hauv qab no.
Los ntawm theem nrab 'auto sensitization' kis, kev tsis haum tshuaj tiv thaiv kab mob tuaj yeem qee zaum ua dav dav. Cov tshuaj tiv thaiv yees duab yog tshwm sim los ntawm kev ua kom cov tshuaj pleev ib ce lossis kev tswj hwm tus neeg saib xyuas los ntawm ultraviolet hluav taws xob.
Daim duab 02: Eczema ntiv tes
Kev tswj hwm
Kev tswj kev tiv thaiv kab mob dermatitis tsis yog ib txwm yooj yim. Qhov no yog vim muaj ntau yam sib tshooj. Lub hom phiaj tseem ceeb tshaj plaws yog kev txheeb xyuas qhov ua rau muaj kev ua xua lossis ua rau khaus. Kev ntsuam xyuas thaj ua rau muaj txiaj ntsig zoo hauv dermatitis ntawm lub ntsej muag, tes, thiab ko taw vim nws pab txheeb xyuas cov tshuaj tsis haum. Kev cais tawm ntawm qhov ua txhaum cai los ntawm ib puag ncig yog xav kom tshem tawm dermatitis.
Tab sis qee qhov ua xua xws li Nickel lossis colophony nyuaj rau tshem tawm. Ntxiv mus, nws yog tsis yooj yim sua kom tshem tawm irritants. Kev sib cuag ntawm irritants thaum lub sij hawm tej hauj lwm yog inevitable. Cov khaub ncaws tiv thaiv yuav tsum tau hnav, kev ntxhua khaub ncaws kom txaus thiab ziab yuav tsum tau muab txhawm rau txhawm rau txo qis kev sib cuag nrog cov khaus khaus. Thib ob los tiv thaiv kev ntsuas, cov neeg mob tuaj yeem siv cov tshuaj steroids hauv kev sib cuag dermatitis.
czema herpeticum
Cov menyuam yaus uas muaj kab mob atopic dermatitis muaj kev pheej hmoo siab dua ntawm kev kis kab mob herpes. Qhov no yuav ua rau muaj kev phom sij rau lub neej,
Nummular eczema
npib zoo li qhov txhab tshwm sim ntawm lub cev thiab ob txhais ceg
Page's disease of the mis
kab mob qog noj ntshav nyob ib puag ncig lub txiv mis thiab cov poj niam areola, uas feem ntau yog vim muaj kab mob hauv qab
Lichen simplex
Qhov no yog tus yam ntxwv los ntawm kev tsim ntawm thaj chaw thaj tsam ntawm lichens vim yog rubbing
Neurodermatitis
-
YAsteatotic dermatitis
Ua rau cov neeg laus tshwj xeeb ntawm ob txhais ceg
Stasis eczema
Cov no tshwm sim hauv thaj chaw ntawm venous congestion
Qhov Zoo sib xws ntawm Paget's Disease thiab Eczema yog dab tsi?
ob leeg yog kab mob ntawm cov leeg nqaij
Qhov txawv ntawm Paget's Disease thiab Eczema yog dab tsi?
Paget's disease yog ib qho teeb meem ntawm kev kho pob txha. Eczema yog ib qho mob ntawm daim tawv nqaij uas tshwm sim los ntawm cov pab pawg ntawm cov kab mob vesicular nrog rau qib sib txawv ntawm exudates thiab scaling. Kev hloov pauv caj ces ntseeg tau tias yog qhov ua rau Paget tus kab mob thaum Eczema yog vim muaj qhov tsis txaus ntseeg.
Tshuaj Kho Mob
Cov yam ntxwv ntawm Paget muaj xws li mob pob txha (tsuas yog nyob rau hauv tus txha nqaj qaum lossis lub plab), mob pob txha, pob txha deformities, Neurological deficits vim yog compression ntawm cranial hlab ntsha feem ntau II, V, VII thiab VIII. Spinal stenosis thiab hydrocephalus tuaj yeem tshwm sim, Cov zis siab tsis ua haujlwm, Pathological puas, thiab qee zaum osteogenic sarcomas tuaj yeem tshwm sim.
kab mob eczema tuaj yeem cuam tshuam rau txhua qhov ntawm lub cev. Thaum dermatitis tshwm sim ntawm ib qhov chaw, qhov ntawd qhia tau tias muaj kev sib cuag nrog qee yam khoom. Thaum tus neeg mob muaj keeb kwm ntawm Nickel allergy tshwm sim nrog eczema ntawm lub dab teg nws qhia tias muaj kev tsis haum rau lub watch pluaj buckle. Yog li ntawd, nws yog ib qho yooj yim los sau qhov ua tau los ntawm kev paub tus neeg mob txoj haujlwm, kev nyiam ua, keeb kwm yav dhau los thiab kev siv tshuaj pleev ib ce lossis tshuaj.
Kev tshawb nrhiav
Hais txog paget tus kab mob; X-ray - lytic lesions tuaj yeem pom nyob rau hauv thawj theem ua raws li theem sib xyaw thiab nyob rau theem siab tshaj plaws, kev tsim cov pob txha txawv txav tuaj yeem raug txheeb xyuas, Isotope pob txha scan tuaj yeem siv los txheeb xyuas qhov cuam tshuam ntawm pob txha, thiab Serum alkaline phosphatase. qib nce ntxiv nrog rau qib urinary hydroxyproline. Rau Eczema, Kev kuaj tawv nqaij tuaj yeem siv los txheeb xyuas qhov muaj peev xwm ua xua.
Kev Kho thiab Tswj
Rau paget tus kab mob, Bisphosphonates yog cov tshuaj xaiv hauv kev tswj hwm. Cov chav kawm tshuaj yog muab ncua tsis tu ncua nyob ntawm qib alkaline phosphatase thiab qib urinary hydroxyproline. Thiab kev tswj ntawm eczema tsis yog ib txwm yooj yim vim muaj ntau thiab feem ntau sib tshooj uas tuaj yeem koom nrog hauv ib rooj plaub. Patch test yog tshwj xeeb tshaj yog muaj txiaj ntsig zoo rau cov kab mob dermatitis ntawm lub ntsej muag, tes, thiab ko taw. Nws pab txheeb xyuas cov allergens koom nrog. Tsis tas li ntawd, kev cais tawm ntawm qhov ua txhaum cai ntawm ib puag ncig yog qhov tsim nyog rau kev tshem tawm cov kab mob dermatitis.
Summary – Paget's Disease vs Eczema
Paget's kab mob yog ib qho teeb meem ntawm kev kho pob txha thaum eczema yog ib qho mob ntawm daim tawv nqaij uas tshwm sim los ntawm pab pawg ntawm cov kab mob vesicular nrog rau qib sib txawv ntawm exudates thiab scaling. Kev hloov pauv hauv qee cov noob yog qhov ua rau Paget tus kab mob. Eczema, ntawm qhov tod tes, tshwm sim vim muaj kev tsis haum tshuaj tiv thaiv kab mob tiv thaiv ntau yam tsis haum. Qhov no yog qhov txawv ntawm Paget's Disease thiab Eczema.
