Qhov Tseem Ceeb Qhov txawv - Platelets vs Clotting Factors
ntshav coagulation yog ib qho txheej txheem tseem ceeb. Thaum cov hlab ntsha raug mob lossis raug txiav, nws yuav tsum tiv thaiv kom tsis txhob muaj ntshav ntau dhau los ntawm cov hlab ntshav ua ntej ua rau poob siab lossis tuag. Nws yog ua los ntawm kev hloov cov ntsiab lus tshwj xeeb hauv cov ntshav mus rau hauv cov khoom siv tsis zoo gel zoo li ntawm qhov chaw raug mob. Qhov no yog hu ua ntshav txhaws lossis ntshav coagulation. Vim tias cov txheej txheem no, cov ntshav tsis tu ncua los ntawm cov hlab ntsha raug mob, cov ntaub so ntswg thiab cov khoom nruab nrog cev, raug tso tseg, thiab vim li ntawd, cov teeb meem tuaj yeem raug tiv thaiv sai li sai tau. Ntshav coagulation yog ua tiav los ntawm kev ua cov ntshav txhaws. Cov ntshav txhaws muaj ib lub ntsaws ntawm platelets thiab lub network ntawm insoluble fibrin molecules. Ntshav coagulation feem ntau yog ua los ntawm kev tsim cov fibrin clot. Fibrin yog ib qho insoluble, fibrous thiab non-globular protein uas cuam tshuam cov ntshav txhaws. Nws yog lub hauv paus ntaub polymer ntawm cov ntshav txhaws. Fibrin tsim tshwm sim nyob rau hauv teb rau kev raug mob nyob rau hauv ib feem ntawm lub vascular system los yog lub circulatory system. Thaum muaj kev raug mob, protease enzyme hu ua thrombin ua rau fibrinogen thiab ua rau nws ua polymerize rau hauv fibrin, uas yog ib qho insoluble gel zoo li protein. Tom qab ntawd fibrin ua ke nrog platelets tsim cov ntshav txhaws ntawm qhov chaw mob kom tsis txhob los ntshav ntxiv. Platelets yog ib hom ntawm cov qe ntshav, uas yuav tsum tau muaj nyob rau hauv cov txheej txheem ntawm cov ntshav txhaws. Clotting yam yog cov khoom nyob rau hauv cov ntshav uas ua sequentially tsim thiab ntxiv dag zog rau cov ntshav txhaws kom txhob los ntshav. Qhov no yog qhov sib txawv tseem ceeb ntawm platelets thiab clotting yam.
Platelets yog dab tsi?
Platelets yog cov hlwb me me uas pom nyob hauv cov ntshav ntau. Platelets tseem hu ua thrombocytes. Lawv tsis muaj nucleus. Platelets suav txog ze li 20% ntawm tag nrho cov qe ntshav suav. Txoj kab uas hla ntawm platelet nyob nruab nrab ntawm 3 mus rau 4 μm. Ib tug neeg noj qab nyob zoo muaj platelet suav ntawm 150,000 txog 450,000 ib µl ntawm cov ntshav. Los ntawm kev suav tag nrho cov ntshav, platelet suav tuaj yeem kwv yees hauv cov ntshav. Lub neej ntawm platelet yog 8 mus rau 10 hnub. Platelets yog tsim los ntawm cov pob txha pob txha ntawm peb lub cev. Lub luag haujlwm tseem ceeb ntawm platelets yog los pab txhawb cov txheej txheem ntawm cov ntshav txhaws los ntawm kev tsim cov platelet ntsaws rau thawj theem ntawm cov ntshav txhaws.
Platelets kuj tsim cov platelet yam 3 uas tseem ceeb hauv cov txheej txheem tshuaj tiv thaiv ntawm coagulation. Thaum qhov kev ncaj ncees ntawm cov hlab ntsha raug cuam tshuam los ntawm kev raug mob, circulating platelets thiab lwm yam ua ke nyob ze ntawm qhov chaw raug mob. Prostaglandins xws li thromboxane pab cov txheej txheem ntawm platelet aggregation thiab qhov no yog ua raws li los ntawm kev tsim cov fibrin network ntawm qhov chaw ntawm kev raug mob los tiv thaiv kev poob ntshav ntxiv.
Cov kab mob platelets tuaj yeem ua rau ntau qhov tsis sib xws hauv lub cev. Qee cov tshuaj noj qab haus huv xws li tshuaj aspirin (cov tshuaj uas tsis yog tshuaj steroidal anti-inflammatory) yog siv los tiv thaiv cov ntshav txhaws los ntawm kev cuam tshuam cov kauj ruam tshwj xeeb ntawm platelet aggregation.
Daim duab 01: Platelets
Cov qib platelets txawv txav hauv cov ntshav ua rau qee yam mob hauv lub cev. Thrombocytopenia yog ib yam mob uas tshwm sim los ntawm qhov qis qis ntawm platelets hauv cov ntshav. Thrombocytopenia kuj tseem tuaj yeem tshwm sim los ntawm qee yam kab mob xws li Dengue, qhov twg tus kab mob no muaj peev xwm ua kom cov platelets puas tsuaj ua rau cov ntshav platelet txo qis sai.
Dab tsi yog Clotting Factors?
Clotting factors yog cov khoom hauv cov ntshav uas ua haujlwm ua ntu zus los tsim cov ntshav txhaws thiab tso tseg los ntshav. Lawv kuj tseem hu ua coagulation yam. Muaj ntau hom kev sib txawv ntawm cov khoom sib txawv xws li soluble plasma yam. Ntawm lawv, qee qhov yog cov plasma proteins thaum qee qhov tsis muaj ions kuj pom.
Daim duab 02: Txheej Txheem Coagulation
Qee qhov tseem ceeb ntawm cov ntshav txhaws tau teev tseg hauv qab no nrog lawv lub luag haujlwm thaum lub sijhawm tsim cov ntshav txhaws.
- Fibrinogen yog cov plasma protein uas tsim los ntawm lub siab thiab hloov mus ua fibrin.
- Prothrombin yog lwm cov plasma protein uas ua ke los ntawm lub siab thiab hloov fibrinogen rau hauv fibrin.
- Cov ntaub so ntswg yog cov plasma membrane glycoprotein uas ua rau txoj hauv kev ntawm cov ntshav txhaws.
- Calcium ions kuj xav tau rau tag nrho cov txheej txheem ntawm coagulation.
- Proaccelerin, uas yog cov plasma protein, yog qhov tseem ceeb rau txoj hauv kev ntawm coagulation.
- Antihemophilic yam yog ib qho plasma protein uas yuav tsum tau rau txoj hauv kev sab hauv.
- Plasma thromboplastin tivthaiv kuj yog cov plasma protein uas yog qhov tseem ceeb rau txoj hauv kev.
- Stuart yam cuam tshuam nrog txoj hauv kev.
- Plasma thromboplastin antecedent yog ib qho tseem ceeb ntawm txoj hauv kev.
- Hageman yam yog qhov tseem ceeb ntawm txoj hauv kev uas ua rau plasmin.
- Fibrin stabilizing yam yog ib qho plasma protein uas tsim nyog rau kev tsim cov kab sib txuas ntawm fibrin los tsim kom muaj zog, ruaj khov.
- Fletcher yam yog plasma protein uas ua rau Hageman factor.
Dab tsi yog qhov zoo sib xws ntawm Platelets thiab Clotting Factors?
- Platelets thiab cocotting yam muaj nyob hauv cov ntshav.
- Ob leeg Platelets thiab Clotting Factors yog cov khoom cuam tshuam hauv cov ntshav coagulation.
- Ob leeg Platelets thiab Clotting Factors muaj qhov tseem ceeb tshaj plaws hauv kev tso ntshav.
Qhov txawv ntawm Platelets thiab Clotting Factors yog dab tsi?
Platelets vs Clotting Factors |
|
| Platelets yog cov qe ntshav me me uas tsim nyog los tsim cov ntshav txhaws kom tsis txhob los ntshav. | Clotting Factors yog cov tshuaj ntawm cov ntshav uas koom nrog cov txheej txheem ntshav coagulation. |
| hom | |
| Platelets yog anucleated me me disk zoo li hlwb. | Cov khoom ua kom ntshav yog cov plasma proteins, inorganic ions lossis plasma membrane glycoproteins. |
Summary – Platelets vs Clotting Factors
ntshav txhaws yog ib qho tseem ceeb ntawm cov txheej txheem uas tshwm sim sai tom qab cov hlab ntsha raug mob. Nws tiv thaiv cov ntshav ntau dhau thiab cov ntshav poob uas tuaj yeem ua rau tuag taus. Ntau yam ntawm cov ntshav tau koom nrog hauv cov ntshav coagulation. Ntawm lawv, platelets thiab coagulation yam tseem ceeb los yog cov ntshav txhaws yog ob yam tseem ceeb. Platelets yog cov hlwb me me ntawm cov ntshav uas tsim cov platelet ntsaws los thaiv qhov chaw raug mob thiab tiv thaiv los ntshav. Clotting yam yog cov tshuaj ntawm cov ntshav uas ua raws li qhov ua tau thiab tsim kom muaj kev ruaj khov thiab muaj zog fibrin ntshav txhaws ntawm qhov chaw raug mob. Qhov no yog qhov txawv ntawm cov platelets thiab cov ntshav txhaws.
