Qhov Tseem Ceeb Qhov txawv - Muscular Dystrophy vs Myasthenia Gravis
Lub cev txav tau tshwm sim los ntawm kev sib koom tes ntawm cov leeg nqaij thiab cov txheej txheem neuronal uas tswj lawv. Yog li ntawd, txhua yam tsis ua hauj lwm lossis kev sib tsoo ntawm cov khoom no tuaj yeem cuam tshuam kev txav mus los ntawm tus neeg. Hauv myasthenia gravis thiab cov leeg nqaij dystrophy, muaj cov kev txwv rau lub cev txav mus los. Ib qho kev poob ntawm cov leeg nqaij loj thiab qhov ua rau poob ntawm cov leeg muaj zog yog cov yam ntxwv ntawm cov leeg nqaij dystrophy. Ntawm qhov tod tes, myasthenia gravis yog ib qho kab mob autoimmune uas tshwm sim los ntawm kev tsim cov tshuaj tiv thaiv kab mob uas thaiv kev sib kis ntawm impulses hla cov kab mob neuromuscular. Qhov sib txawv tseem ceeb ntawm ob qhov kev tsis sib haum xeeb yog, hauv myasthenia gravis qhov teeb meem yog nyob rau theem ntawm neuromuscular junctions tab sis nyob rau hauv cov leeg nqaij dystrophy, qhov txhab yog nyob rau hauv cov leeg.
Dab tsi yog Muscular Dystrophy?
Kev poob ntawm cov nqaij pob txha thiab qhov tshwm sim ntawm cov leeg nqaij muaj zog yog cov yam ntxwv ntawm cov leeg nqaij dystrophy. Kev hloov caj ces, tshwj xeeb tshaj yog nyob rau hauv cov noob dystrophin, ntseeg tau tias yog qhov ua rau ntawm qhov teeb meem no. Muaj ntau ntau yam ntawm cov leeg nqaij dystrophy tawm ntawm Duchenne leeg nqaij dystrophy yog qhov ntau tshaj.
Symptoms and Signs
Cov tsos mob thaum ntxov muaj xws li:
- Muscles mob stiffness
- Txoj kev nyuaj siab
- Imbalance
- kawm nyuaj
Kev tshwm sim lig suav nrog:
- Ua pa tsis taus vim tsis muaj zog ntawm cov leeg ua pa
- Kev tsis muaj zog
- Pab mob plawv
- Shortening nqaij thiab tendons
Kev tshawb nrhiav
Feem ntau, cov nqaij ntshiv yog ua tiav rau lub hom phiaj ntawm kev txheeb xyuas cov kab mob sib txawv ntawm cov leeg nqaij dystrophy.
Daim duab 01: Muscular Dystrophy
Kev kho mob
- Tsis muaj kev kho qhov tseeb, tsuas yog tswj cov tsos mob xwb
- Gene kho raws li kev kho mob rau cov leeg nqaij dystrophy yog nce kub
- Tshuaj xws li corticosteroids tau muab los tswj kev mob
- ACE inhibitors thiab beta blockers muaj txiaj ntsig hauv kev tswj cov mob plawv
- Kev kho lub cev tuaj yeem muab tau ua ib qho ntxiv rau cov kws kho mob
Myasthenia Gravis yog dab tsi?
Myasthenia gravis yog ib qho kab mob autoimmune uas tshwm sim los ntawm kev tsim cov tshuaj tiv thaiv kab mob uas thaiv kev sib kis ntawm impulses hla cov kab mob neuromuscular. Cov tshuaj tiv thaiv no khi rau postsynaptic Ach receptors yog li tiv thaiv kev khi ntawm Ach hauv synaptic cleft rau cov receptors. Cov poj niam muaj tsib zaug cuam tshuam los ntawm tus mob no ntau dua li txiv neej. Muaj kev koom tes tseem ceeb nrog rau lwm yam kab mob autoimmune xws li mob caj dab rheumatoid, SLE, thiab autoimmune thyroiditis. Concurrent thymic hyperplasia tau pom.
Tshuaj Kho Mob
- Muaj qhov tsis muaj zog ntawm cov leeg nqaij limb, cov leeg sab nraud, thiab cov leeg pob txha
- muaj zog thiab hloov pauv ntawm cov leeg tsis muaj zog
- Tsis mob leeg
- Lub plawv tsis cuam tshuam tab sis cov leeg ua pa tuaj yeem cuam tshuam
- Reflexes kuj fatigable
- Diplopia, ptosis, thiab dysphagia
Kev tshawb nrhiav
- Anti ACh receptor antibodies hauv cov ntshav
- Tensilon kuaj qhov twg koob tshuaj edrophonium raug tswj hwm uas ua rau muaj kev txhim kho ib ntus ntawm cov tsos mob uas kav ntev li 5 feeb
- Kev Tshawb Fawb
- ESR and CRP
Daim duab 02: Ptosis hauv Myasthenia Gravis
Kev tswj hwm
- Kev tswj hwm ntawm anticholinesterases xws li pyridostigmine
- Immunosuppressants xws li corticosteroids tuaj yeem muab rau cov neeg mob uas tsis teb rau anticholinesterases
- YThymectomy
- Plasmapheresis
- YIntravenous immunoglobulins
Dab tsi yog qhov zoo sib xws ntawm Cov Muscular Dystrophy thiab Myasthenia Gravis?
Ob leeg tuaj yeem cuam tshuam kev txav mus los ntawm tus neeg mob hnyav
Dab tsi yog qhov txawv ntawm Muscular Dystrophy thiab Myasthenia Gravis?
Muscular Dystrophy vs Myasthenia Gravis |
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Kev poob ntawm cov nqaij pob txha thiab qhov tshwm sim ntawm cov leeg nqaij muaj zog yog cov yam ntxwv ntawm cov leeg nqaij dystrophy. | Myasthenia gravis yog ib qho mob autoimmune yam ntxwv los ntawm kev tsim cov tshuaj tiv thaiv kab mob uas thaiv kev sib kis ntawm impulses hla cov hlab ntsha neuromuscular. |
Defect | |
Kev tsis haum yog nyob rau hauv cov leeg | Tsis raug yog ntawm cov kab mob neuromuscular junctions |
Tshuaj kho mob | |
Cov tsos mob thaum ntxov muaj xws li:
Kev tshwm sim lig suav nrog:
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kho mob nta yog, · Muaj cov leeg tsis muaj zog ntawm cov leeg leeg, cov leeg sab nraud, thiab cov leeg pob txha · Muaj qaug zog thiab hloov pauv ntawm cov leeg tsis muaj zog · Tsis mob leeg · Lub plawv tsis cuam tshuam tab sis cov leeg ua pa tuaj yeem cuam tshuam · Reflexes kuj fatigable · Diplopia, ptosis, thiab dysphagia |
Tshawb nrhiav | |
Feem ntau, cov nqaij ntshiv yog ua tiav rau lub hom phiaj ntawm kev txheeb xyuas cov kab mob sib txawv ntawm cov leeg nqaij dystrophy. |
Kev tshawb nrhiav tau ua tiav thaum xav tias myasthenia gravis. · Anti ACh receptor antibodies hauv cov ntshav · Tensilon test qhov twg txhaj koob tshuaj edrophonium uas ua rau muaj kev txhim kho ib ntus ntawm cov tsos mob uas kav ntev li 5 feeb · Kev tshawb fawb txog duab · ESR thiab CRP |
Kev tswj hwm | |
· Tsis muaj kev kho kom meej, tsuas yog tswj cov tsos mob xwb · Gene kho raws li kev kho mob rau cov leeg nqaij dystrophy tau txais cua sov · Cov tshuaj xws li corticosteroids raug muab los tswj kev mob · ACE inhibitors thiab beta blockers muaj txiaj ntsig zoo hauv kev tswj cov mob plawv · Kev kho lub cev tuaj yeem muab tau ua ib qho ntxiv rau cov kws kho mob |
· Kev tswj hwm ntawm anticholinesterases xws li pyridostigmine · Cov tshuaj tiv thaiv kab mob xws li corticosteroids tuaj yeem muab rau cov neeg mob uas tsis teb rau anticholinesterases · Thymectomy · Plasmapheresis · Intravenous immunoglobulins |
Summary – Muscular Dystrophy vs Myasthenia Gravis
Ib qho kev poob ntawm cov nqaij pob txha thiab qhov ua rau poob ntawm cov leeg lub zog yog cov yam ntxwv ntawm cov leeg nqaij dystrophy whereas myasthenia gravis yog ib qho kab mob autoimmune uas tshwm sim los ntawm kev tsim cov tshuaj tiv thaiv uas thaiv kev sib kis ntawm impulses hla cov hlab ntsha neuromuscular. Nyob rau hauv cov leeg nqaij dystrophy, qhov tsis xws luag yog nyob rau hauv cov leeg, tab sis nyob rau hauv myasthenia gravis, qhov tsis xws luag yog nyob rau hauv lub neuromuscular hlws ris. Qhov no yog qhov sib txawv ntawm ob qhov teeb meem.
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Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li daim ntawv ceeb toom. Thov rub tawm PDF version ntawm no: Qhov txawv Ntawm Cov Muscular Dystrophy thiab Myasthenia Gravis