Qhov Tseem Ceeb Qhov txawv - General vs Specific Transcription Factors
Cov ntsiab lus hloov pauv yog xav tau los ntawm RNA polymerase los ua rau DNA qauv strand hauv kev sib txuas mRNA. Muaj ntau hom kev hloov pauv ntau yam. Cov kev hloov pauv no tsim ib qho nyuaj nrog DNA strand. Lawv hloov qhov kev lees paub ntawm cov qauv strand los yog ua kom muaj kev sib raug zoo ntawm RNA polymerase enzyme ntawm mRNA synthesis nyob rau hauv tus txheej txheem ntawm hu ua transcription. Muaj ob hom kev hloov pauv tseem ceeb. Lawv yog General lossis Basal transcription yam thiab cov yam ntxwv tshwj xeeb Transcription. General transcription yam yog cov yam uas siv los tsim lub pre-initiation complex thaum tus txheej txheem ntawm transcription. Lawv muaj nyob rau hauv yuav luag tag nrho cov eukaryotes, thiab nyob rau hauv prokaryotes, lawv tsim ib tug complex complex. Cov kev hloov pauv tshwj xeeb yog cov kev txhawb nqa lossis kev tawm tsam, uas yog cov txheej txheem DNA tshwj xeeb uas qhib lossis ua rau cov txheej txheem kev hloov pauv dav dav. Qee qhov kev hloov pauv tshwj xeeb tuaj yeem hloov DNA ntu nws tus kheej. Qhov sib txawv tseem ceeb ntawm cov txheej txheem kev hloov pauv dav dav thiab cov ntsiab lus tshwj xeeb yog nyob ntawm kev ua haujlwm. Cov txheej txheem kev hloov pauv dav dav yog koom nrog hauv kev tsim cov txheej txheem ua ntej pib ua ntej ntawm cov txheej txheem kev hloov pauv, qhov tshwj xeeb cov ntaub ntawv hloov pauv tau koom nrog hauv kev ua kom lossis ua rau cov txheej txheem hloov pauv.
Dab tsi yog cov ntsiab lus tseem ceeb?
General lossis Basal transcription yam tseem ceeb yog qhov tseem ceeb uas koom nrog hauv kev tsim cov kev pib ua haujlwm thaum lub sijhawm sau ntawv. Lawv yog cov tseem ceeb rau cov txheej txheem transcription li no, lawv ua lub luag haujlwm tseem ceeb hauv kev ua tiav cov ntawv sau. Muaj rau lub ntsiab lus tseem ceeb ntawm kev sau ntawv. Lawv yog; TFIID, TFIIB, TFIIH, TFIIE, TFIIF, and TFIIA. Lawv ua lub luag haujlwm sib txawv thaum tsim cov kev pib ua haujlwm.
- TFIID - Qhov kev hloov pauv no (TF) tau koom nrog hauv kev lees paub cov txheej txheem txhawb nqa (TATA lub thawv).
- TFIIB - Tus txhawb nqa / TFIID complex tau lees paub los ntawm TFIIB. Qhov no muab lub teeb liab rau kev khi ntawm lub ntsiab catalyzing enzyme RNA polymerase.
- TFIIF - Qhov kev hloov pauv no yog khi rau RNA polymerase. TFIIF yog li koom nrog hauv cov txheej txheem los ntawm kev nrhiav RNA polymerase rau qhov chaw raug.
- TFIIE thiab TFIIH - Kev khi ntawm cov kev hloov pauv no cim qhov kawg ntawm kev tsim ua ntej pib Kev khi ntawm cov no ua rau muaj txiaj ntsig ntawm kev tsim cov txheej txheem ua ntej pib.
- TFIIA txhawb nqa kev khi ntawm TFIID rau lub thawv TATA.
Daim duab 01: Cov Ntsiab Lus Tshaj Tawm dav dav
Cov lus hais saum toj no yog qhov tshwj xeeb rau RNA polymerase II, uas yog hom RNA polymerase uas elongates mRNA strand. Muaj cov kev hloov pauv dav dav cuam tshuam nrog RNA polymerase I thiab III. Cov kev hloov pauv dav dav kuj tseem yuav txawv raws li hom cell uas nws ua rau.
Dab tsi yog qhov tshwj xeeb tshaj tawm?
Tshwj xeeb Transcription Factors yog thaj chaw uas nyob hauv DNA ib ntus thiab. Lawv feem ntau yog cov txhawb nqa lossis cov neeg tawm tsam. Cov kev hloov pauv tshwj xeeb yog cov cis-ua yeeb yam tshwj xeeb hauv cov qauv DNA strand uas tau txais kev hloov pauv. Kev ua kom cov kev txhim kho tshwj xeeb thiab cov neeg tawm tsam koom nrog hauv kev ua kom muaj kev sib raug zoo ntawm cov enzyme los ntawm kev hloov cov kev taw qhia ntawm DNA molecule los yog los ntawm kev ua raws li cov cheeb tsam qhia. Cov kev hloov pauv tshwj xeeb kuj tau siv los txhawb kev hloov kho rau DNA template strand. Cov kev hloov kho no feem ntau yog kev hloov kho covalent xws li methylation. Yog li ntawd, thaj chaw methylated DNA ua haujlwm tshwj xeeb los yog cov neeg tawm tsam ntawm cov txheej txheem sau ntawv.
Daim duab 02: Cov Ntsiab Lus Qhia tshwj xeeb
Cov kev hloov pauv tshwj xeeb yog nyob ntawm hom hom thiab tsis pom muaj nyob hauv txhua tus eukaryotes. Cov kev hloov pauv no tau qhib los ntawm cov txheej txheem metabolic sib txawv ntawm txoj kev teeb liab transduction. Thaum ua kom tiav, lawv tswj cov kev qhia ntawm cov noob nyob rau theem kev hloov pauv.
Dab tsi yog qhov zoo sib xws ntawm General thiab Specific Transcription Factors?
- Ob yam yuav tsum tau muaj nyob rau hauv tus txheej txheem ntawm kev sau.
- Ob qho xwm txheej cuam tshuam rau cov noob qhia ntawm lub cev.
- Ob qho tib si pab tswj kev ua haujlwm ntawm RNA polymerase hauv cov txheej txheem sau ntawv.
- Ob qho xwm txheej pom muaj feem ntau hauv eukaryotes.
Dab tsi yog qhov txawv ntawm General thiab Specific Transcription Factors?
General vs Specific Transcription |
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| Cov ntsiab lus dav dav yog cov khoom siv uas tau siv los ua qhov kev pib ua ntej ua ntej thaum txheej txheem sau ntawv. | Cov kev hloov pauv tshwj xeeb yog cov kev txhawb nqa lossis kev tawm tsam, uas yog cov DNA tshwj xeeb uas ua rau lossis ua rau cov txheej txheem kev hloov pauv dav dav. |
| Hom Molecule | |
| Cov ntsiab lus dav dav yog cov protein raws li. | Txoj kev hloov pauv tshwj xeeb yog nucleotide sequences. |
| Cov ntsiab lus dav dav ua rau qhov kev pib ua ntej ua ntej thaum pib qhov kev hloov pauv. | Cov ntsiab lus tshwj xeeb ua raws li kev txhim kho lossis kev tawm tsam ntawm kev sau ntawv. |
| Hom | |
| Muaj rau hom loj; TFIID, TFIIB, TFIIH, TFIIF, TFIIE, thiab TFIIA of general transcription factors. | Txoj kev hloov pauv tshwj xeeb yog feem ntau categorized li enhancers thiab repressors. |
Summary – General vs Specific Transcription Factors
Cov ntsiab lus hloov pauv yog qhov tseem ceeb rau kev tswj hwm kev hloov pauv thiab yuav tsum tau ua kom muaj txiaj ntsig thiab raug ntawm cov txheej txheem. Transcription yam yog ob hom loj; General / Basal thiab Specific. Cov kev hloov pauv dav dav tau koom nrog hauv kev tsim cov txheej txheem ua ntej pib thaum lub sijhawm hloov pauv, qhov tshwj xeeb cov ntaub ntawv hloov pauv yog thaj chaw hauv DNA nws tus kheej uas ua raws li kev txhim kho lossis kev tawm tsam. Cov ntsiab lus hloov pauv dav dav yog cov protein raws thiab xav tau los ntawm txhua tus eukaryotes. Nws tsis yog varied dav thiab tseem zoo li niaj hnub molecules. Ib qho kev hloov pauv tshwj xeeb tuaj yeem sib txawv dav thiab nyob ntawm tus tib neeg cov caj ces pleev. Qhov no yog qhov sib txawv ntawm qhov dav dav thiab cov ntsiab lus tshwj xeeb.
Download PDF Version of General vs Specific Transcription Factors
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li daim ntawv ceeb toom. Thov rub tawm PDF version ntawm no Qhov txawv ntawm General thiab Specific Transcription Factors
