Qhov Tseem Ceeb Qhov txawv - Kab Mob Coronary Artery vs Atherosclerosis
Atherosclerosis yog ib yam mob ntawm cov hlab ntsha uas yog tus cwj pwm los ntawm kev tsim cov roj deposits hauv phab ntsa hlab ntsha. Thaum atherosclerosis tshwm sim nyob rau hauv cov hlab ntsha coronary muaj ib qho occlusion ntawm arterial lumen uas ua rau txo qis hauv myocardial perfusion uas xaus li myocardial ischemia. Tus mob no raug txheeb xyuas raws li tus kab mob coronary artery. Raws li qhov tshwm sim, atherosclerosis yog qhov tshwm sim pathological uas ua rau muaj kab mob plawv. Qhov no yog qhov sib txawv tseem ceeb ntawm cov kab mob coronary artery thiab atherosclerosis.
Kab mob Coronary Artery yog dab tsi?
Ntshav muab rau cov leeg myocardial tshwm sim los ntawm cov hlab ntsha coronary. Lub occlusion ntawm cov hlab ntsha yog li cuam tshuam cov ntshav muab rau myocardium thiab thaum kawg ua rau myocardial ischemia yog hu ua kab mob coronary artery.
Kev cuam tshuam ntawm cov hlab ntsha tuaj yeem tshwm sim vim muaj ntau yam xws li atherosclerosis, thromboembolic txheej xwm, vascular spasms thiab lwm yam.
Risk Factors
- Nonmodifiable risk factors
- hnub nyoog
- Txiv neej poj niam
- tsev neeg keeb kwm
- Ntxhais tsis xws luag
- Modifiable risk factors
- Hypertension
- Smoking
- Tsis muaj kev tawm dag zog
- YHomocysteineemia
- Kev rog
- Gout
Tshuaj Kho Mob
Cov ischemia txuam nrog CAD ua rau muaj qhov mob ischemic uas hu ua angina. Feem ntau muaj qhov mob hauv nruab nrab retrosternal hauv siab uas tawm mus rau lub puab tsaig lossis caj npab. Qhov mob no muaj qhov tsis xis nyob thiab feem ntau, tawm hws txawv txav nrog rau kev ntshai. Tus neeg mob tuaj yeem ua tsis taus pa.
Muaj ntau yam sib txawv ntawm angina raws li tau piav qhia hauv qab no;
- Exertional Angina - qhov no yog qhov tsis xis nyob hauv pem hauv ntej ntawm lub hauv siab uas ua rau muaj kev tawm dag zog lub cev, huab cua txias lossis kev ntxhov siab. Qhov mob feem ntau zoo li ob peb feeb tom qab so ntawm qhov xwm txheej uas ua rau nws tshwm sim.
- Stable Angina - angina tau piav qhia tias yog angina ruaj khov thaum tsis muaj qhov hloov pauv ntawm nws qhov zaus, sijhawm lossis qhov hnyav
- Tsis ruaj tsis khov Angina - angina ntawm qhov pib tsis ntev los no lossis kev puas tsuaj ntawm angina yav tas los ruaj khov yog hu ua tsis ruaj khov agina.
- Refractory Angina - hauv cov neeg mob uas muaj kab mob plawv loj heev uas tsis tuaj yeem rov ua kom rov ua tau thiab tus neeg mob tsis teb rau kev kho mob muaj refractory angina.
- Variant angina - ib qho kev mob angina uas tsis tau paub yog hu ua variant angina
Ntxiv rau qhov mob angina, tuaj yeem muaj lwm yam kev kho mob xws li,
- Nyob
- Edema ntawm thaj chaw nyob
- Dyspnea
- Orthopnea
- Paroxysmal nocturnal dyspnea
Kev Tshawb Fawb thiab Kev Tshawb Fawb
Kev kuaj mob tau txais kev txhawb nqa los ntawm kev tshawb nrhiav hauv qab no
- ECG
- SPECT
- CT coronary angiography
- Kev ntxhov siab echocardiography
Daim duab 01: CAD
Kev tswj hwm
Kev tswj hwm ntawm CAD txawv nyob ntawm seb qhov kev cuam tshuam ntawm cov hlab ntsha. Kev tswj hwm cov kev pheej hmoo tseem ceeb heev. Tus neeg mob tuaj yeem muab tso rau kev kho mob thiab ua raws li txhawm rau txheeb xyuas qhov kev txhim kho ntawm cov tsos mob. Thaum cov kev kho mob ua tsis tiav, kev phais kev phais xws li cov hlab ntsha coronary bypass grafting percutaneous coronary intervention (PCI) tau ua.
Atherosclerosis yog dab tsi?
Atherosclerosis yog ib yam mob ntawm cov hlab ntsha uas yog tus cwj pwm los ntawm kev tsim cov roj deposits hauv phab ntsa hlab ntsha.
Muaj ntau yam sib txawv thiab kev sib txawv uas ua rau muaj kev txhim kho atherosclerosis. Cov kev pab cuam no tuaj yeem muab faib ua ob pawg raws li qhov hloov pauv tau thiab cov yam tsis hloov pauv tau.
Modifiable Factors
- Hypertension
- mob khaub thuas
- Kev haus luam yeeb
Nonmodifiable Factors
- Ntxhais tsis xws luag
- tsev neeg keeb kwm
- nce hnub nyoog
- Txiv neej poj niam
YPathogenesis ntawm Atherosclerosis
"Tshuaj rau kev raug mob" yog qhov kev lees paub dav dav tshaj plaws uas piav qhia txog qhov tshwm sim ntawm tus mob no los ntawm kev sib koom ua ke ntawm cov xwm txheej uas tau hais tseg saum toj no nrog cov xwm txheej pathological tshwm sim hauv phab ntsa hlab ntsha. Qhov kev xav no qhia txog xya-kauj ruam rau kev txhim kho ntawm atheroma.
- Endothelial raug mob thiab ua haujlwm tsis zoo uas ua rau nce vascular permeability, leukocyte adhesion thiab qhov muaj feem ntawm thrombosis.
- Cov lipids hauv cov phab ntsa ntawm cov hlab ntsha. LDL thiab nws cov oxidized cov ntaub ntawv yog hom roj uas sau abundantly.
- Monocyte adhesion rau endothelium. Cov monocytes no ces tsiv mus rau hauv intima thiab hloov mus ua npuas hlwb lossis macrophages.
- Platelet adhesion
- Cov platelets, macrophages thiab lwm yam ntau hom hlwb uas tau khaws cia ntawm qhov chaw raug mob pib tso tawm cov tshuaj sib txawv sib txawv uas pib ua haujlwm ntawm cov leeg nqaij leeg los ntawm kev tshaj tawm lossis los ntawm cov neeg ua ntej.
- Cov neeg ua haujlwm tau txais cov leeg nqaij du proliferate thaum sib txuas cov tshuaj matrix extracellular thiab nyiam T hlwb ntawm lub nkoj puas.
- Lipid accumulates ob qho tib si extracellularly thiab intracellularly (hauv macrophages thiab cov leeg nqaij du) tsim cov atheroma.
Morphology
Ob lub cim morphological ntawm atherosclerosis yog muaj cov rog streaks thiab atheromas.
Fatty streaks muaj foamy macrophages uas muaj lipids. Thaum pib, lawv tshwm raws li me me daj me ntsis thiab tom qab ntawd lawv coalesce ua streaks uas feem ntau yog nyob ib ncig ntawm 1cm ntev. Txij li thaum lawv tsis txaus siab los ntawm qhov chaw, cov ntshav ntws los ntawm lub nkoj tsis cuam tshuam. Txawm hais tias cov rog rog tuaj yeem nkag mus rau hauv atheromas, feem ntau ntawm lawv ploj mus. Cov aortas ntawm cov menyuam mos noj qab haus huv thiab cov tub ntxhais hluas tuaj yeem muaj cov rog rog no.
Daim duab 02: Ib hom kab mob ntawm Aorta uas tau mob Atherosclerosis
Cov Teeb Meem ntawm Atherosclerosis
Atherosclerosis feem ntau cuam tshuam rau cov hlab ntsha loj xws li aorta thiab cov hlab ntsha nruab nrab xws li cov hlab ntsha coronary. Txawm hais tias nws muaj peev xwm ua tau rau cov txheej txheem pathological no tshwm sim nyob txhua qhov chaw hauv lub cev, ib tus neeg tuaj yeem ua cov tsos mob tsuas yog thaum atherosclerosis ua rau cov hlab ntsha uas muab lub plawv, hlwb thiab qis qis. Yog li, cov teeb meem loj ntawm atherosclerosis yog,
- mob plawv mob plawv
- Cerebral infarction
- Aortic aneuryms
Qhov txawv ntawm Kab Mob Coronary Artery thiab Atherosclerosis yog dab tsi?
Cov occlusion ntawm occlusion cov hlab ntsha yog li cuam tshuam cov ntshav mus rau myocardium thiab thaum kawg ua rau myocardial ischemia yog hu ua kab mob coronary artery. | Atherosclerosis yog ib yam mob ntawm cov hlab ntsha uas yog tus cwj pwm los ntawm kev tsim cov roj deposits hauv phab ntsa hlab ntsha. |
hom | |
CAD yog kab mob tshwm sim vim yog atherosclerosis tshwm sim hauv cov hlab ntsha. | Atherosclerosis yog cov xwm txheej pathological uas ua rau CAD |
Summary – Coronary Artery Disease vs Atherosclerosis
Cov occlusion ntawm occlusion cov hlab ntsha yog li cuam tshuam cov ntshav mus rau myocardium thiab thaum kawg ua rau myocardial ischemia yog hu ua kab mob plawv. Ntawm qhov tod tes, atherosclerosis yog ib qho kev mob ntawm cov hlab ntsha uas yog tus cwj pwm los ntawm kev tsim cov roj deposits hauv phab ntsa hlab ntsha. Tus kab mob coronary artery yog vim atherosclerosis uas tshwm sim hauv cov hlab ntsha. Qhov no yog qhov txawv ntawm ob qho xwm txheej.
Download the PDF Version of Coronary Artery Disease vs Atherosclerosis
Koj tuaj yeem rub tawm PDF version ntawm kab lus no thiab siv nws rau offline hom phiaj raws li daim ntawv ceeb toom. Thov download PDF version ntawm no Qhov txawv Ntawm Kab Mob Coronary Artery thiab Atherosclerosis