Hodgkin vs Non-Hodgkin Lymphoma
Hodgkin thiab Non-Hodgkin yog ob yam tseem ceeb ntawm cov qog nqaij hlav lymphocyte. Muaj ntau qhov sib txawv ntawm ob qho xwm txheej thaum qee qhov kev nthuav qhia, kev tshawb nrhiav thiab kev kho mob dav dav yog tib yam rau Hodgkin thiab Non-Hodgkin lymphomas. Kab lus no piav qhia txog cov yam ntxwv kho mob, cov tsos mob, ua rau, kev tshawb nrhiav thiab kev kuaj mob, txoj kev kho mob, thiab kev soj ntsuam ntawm Hodgkin thiab Non-Hodgkin lymphoma thiab qhia txog qhov sib txawv ntawm ob qho tib si.
Hodgkin Lymphoma
Hodgkin lymphoma yog hom malignant proliferation ntawm lymphocytes. Qhov no yog ob zaug ntau dua rau cov poj niam xws li txiv neej. Ob tus neeg laus thiab cov neeg laus tuaj yeem tau txais Hodgkin lymphoma vim muaj ob lub hnub nyoog siab tshaj. Muaj tsib hom Hodgkin lymphoma. Lawv yog classical Hodgkin lymphoma, nodular sclerosing, sib xyaw cellularity, lymphocyte nplua nuj thiab lymphocyte depleted Hodgkin lymphomas. Feem ntau qhov kev tsis txaus siab ntawm cov lymphomas no yog lymph node o. 25% ntawm cov neeg mob kuj yws yws ntawm lethargy, kub taub hau, tawm hws hmo ntuj thiab poob phaus. Cawv yuav ua rau mob rau cov neeg mob Hodgkin. Ua npaws yog yam ntxwv tab sis tsis tshua muaj. Nws yog hu ua Pel-Ebstein ua npaws thiab nws hloov pauv ntawm kub taub hau thiab lub sijhawm ntev ntawm qhov qub / qis qis.
Ntawm qhov chaw kuaj mob qog nqaij hlav, qhov loj, qhov sib xws, kev txav mus los thiab kev sib tw yuav tsum raug ntsuas. Kev tshawb fawb suav nrog lymph node biopsy, suav ntshav suav tag nrho, ESR, kuaj lub siab thiab lub raum, CT, MRI, hauv siab x-ray. Anemia thiab nce ESR qhia pom qhov tsis zoo. Hodgkin lymphoma yog staged nrog Ann Arbor txoj kev uas sib raug zoo nrog kev kwv yees.
Kauj Ruam 1 - Khaws rau ib cheeb tsam ntawm cov qog nqaij hlav
Theem 2 - Kev koom tes ntawm ob lossis ntau dua cov qog ntshav qog ntshav nyob rau tib sab ntawm lub diaphragm
Theem 3 - Kev koom tes ntawm cov nodes ntawm ob sab ntawm lub diaphragm
Theem 4 - Tshaj dhau ntawm cov nodes
Radiotherapy yog kev kho mob ntawm kev xaiv rau theem 1 thiab 2. Kev kho mob nrog ABVD regimen (Adriamycin, bleomycin, vinblastine, dacarbazine) yog kev kho mob xaiv rau theem 2a lossis siab dua. Kev kho nws tus kheej tuaj yeem ua rau hypothyroidism, ntsws fibrosis, xeev siab, alopecia thiab subfertility hauv cov txiv neej. % xyoo muaj sia nyob yog siab dua 90% hauv 1A lymphocyte predominant kab mob, thiab tsawg dua 40% hauv 4A lymphocyte depleted kab mob.
Non-Hodgkin Lymphoma
Non-Hodgkin lymphoma yog ib pawg neeg sib txawv ntawm cov xwm txheej uas tsis muaj cov hlwb Reed Sternberg. Feem ntau yog B cell lymphomas. Tsis yog txhua qhov chaw nyob nruab nrab ntawm cov qog ntshav qog ntshav. Ntxiv nodal lymphomas nyob ntawm mucosa txuam nrog lymphoid cov ntaub so ntswg. EBV, HIV thiab lwm yam ua rau lub cev tiv thaiv kab mob tau nce qhov tshwm sim ntawm cov qog ntshav qog ntshav tsis yog Hodgkin. Tsis yog Hodgkin lymphomas feem ntau yog asymptomatic, tab sis nws tuaj yeem tshwm sim nrog lymph node o, tawv nqaij, pob txha, plab, lub paj hlwb thiab cov tsos mob ntawm lub ntsws. Staging zoo ib yam li Hodgkin's tab sis tsis tshua tseem ceeb vim hais tias feem ntau muaj cov kab mob sib kis ntawm kev nthuav qhia.
Kev Tshawb Fawb yog tib yam ua rau Hodgkin tus kab mob. Kev kuaj mob hnyav dua yog tias tus neeg mob yog cov neeg laus, cov tsos mob, nrog cov qog nqaij hlav loj dua 10cm lossis anemic ntawm kev nthuav qhia. Cov kab mob qis qis yuav tsis xav tau kev kho mob. Chlorambucil, purine analogues, xov tooj cua kho tau zoo heev.
Qhov txawv ntawm Hodgkin thiab Non-Hodgkin Lymphoma yog dab tsi?
• Hodgkin tus kab mob nta Reed Sternberg cell thaum tsis yog-Hodgkin kab mob.
• Hodgkin tus kab mob nthuav tawm nrog cov qog ntshav qog ua kom loj dua yog qhov tseem ceeb thaum tsis yog-Hodgkin tus kab mob feem ntau asymptomatic.
• Hodgkin's nthuav tawm ntxov thiab muaj kev pom zoo dua thaum Non-Hodgkin nthuav tawm lig nrog cov kab mob sib kis.
• ABVD kev tswj hwm feem ntau siv los kho Hodgkin tus kab mob thaum nws tsis siv rau Non-Hodgkin tus kab mob.
• Staging yog tsim nyog los prognosticate nyob rau hauv Hodgkin tus kab mob thaum lub sij hawm staging yog yuav luag ib txwm tsis tsim nyog vim muaj ntau yam kab mob ntawm kev nthuav qhia.
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