Qhov sib txawv tseem ceeb ntawm misoprostol thiab mifepristone yog misoprostol yog ib qho hluavtaws prostaglandin siv hauv kev rho menyuam tawm kho mob, thaum mifepristone yog hluavtaws steroid siv hauv kev rho menyuam kho mob.
Kev rho menyuam tawm kho mob tshwm sim thaum siv tshuaj los ua kom rho menyuam. Feem ntau, lawv yog lwm txoj hauv kev nqus aspiration lossis dilation thiab curettage. Kev rho menyuam tawm kho mob muaj ntau dua hauv cov chaw xws li Europe, Is Nrias teb, Tuam Tshoj, thiab Tebchaws Meskas. Tsis tas li ntawd, lawv feem ntau ua los ntawm kev siv ob hom tshuaj ua ke: mifepristone ua raws li misoprostol. Thaum tsis muaj mifepristone, misoprostol tuaj yeem siv ib leeg hauv qee qhov kev rho menyuam tawm.
Misoprostol yog dab tsi?
Misoprostol yog ib qho hluavtaws prostaglandin siv hauv kev rho menyuam tawm. Nws kuj tseem muaj txiaj ntsig zoo hauv kev tiv thaiv thiab kho mob plab thiab duodenal ulcers, inducing zog, thiab kho tom qab los ntshav vim tsis zoo contraction ntawm lub tsev menyuam. Nws yog ib qho hluavtaws prostaglandin E1 (PGE1). Thaum siv rau hauv plab hnyuv, nws yog noj los ntawm qhov ncauj. Rau kev rho menyuam, nws yog siv los ntawm nws tus kheej lossis ua ke nrog mifepristone lossis methotrexate. Los ntawm nws tus kheej, misoprostol muaj qhov ua tau zoo ntawm 66% thiab 90% rau kev rho menyuam. Rau kev ua haujlwm induction los yog rho menyuam, nws yog noj los yog muab tso rau hauv qhov chaw mos. Ntxiv mus, nyob rau hauv cov ntaub ntawv ntawm postpartum los ntshav, nws yuav siv tau rectally.
Daim duab 01: Misoprostol
Cov kev mob tshwm sim ntawm kev siv cov tshuaj no yog raws plab, mob plab, yug me nyuam, uterine rupture, mob plab, xeev siab, mob taub hau, flatulence, dyspepsia, ntuav, thiab cem quav. Misoprostol yuav tsum tsis txhob siv yog tias tib neeg tsis haum rau cov tshuaj no lossis lwm yam prostaglandins. Yog li ntawd, misoprostol tau muab tso rau hauv lub cev xeeb tub X qeb los ntawm FDA. Cov tshuaj no tau tsim thawj zaug hauv xyoo 1973. Txawm li cas los xij, misoprostol tau pom zoo los ntawm FDA hauv xyoo 1973. Nws tseem yog tam sim no nyob rau hauv Lub Koom Haum Ntiaj Teb Kev Noj Qab Haus Huv Cov Npe Cov Tshuaj Tseem Ceeb.
Mifepristone yog dab tsi?
Mifepristone yog ib hom tshuaj uas siv nrog rau cov tshuaj xws li misoprostol thiab methotrexate los coj kev rho menyuam tawm thaum cev xeeb tub thiab tswj kev nchuav menyuam ntxov. Nws tseem hu ua RU-486. Nrog kev sib xyaw ua ke, mifepristone yog 97% zoo rau kev rho menyuam thaum 63 hnub ntawm cev xeeb tub. Mifepristone feem ntau yog noj ntawm qhov ncauj. Cov kev mob tshwm sim ntawm cov tshuaj no muaj xws li mob plab, nkees nkees, los ntshav ntawm qhov chaw mos, xeev siab, ntuav, raws plab, kiv taub hau, qaug zog, thiab kub taub hau. Cov kev mob tshwm sim loj yuav muaj xws li los ntshav ntawm qhov chaw mos, kab mob kab mob, thiab kev yug me nyuam.
Daim duab 02: Mifepristone
Mifepristone yog ib qho tshuaj tiv thaiv progestogen thiab ua haujlwm los ntawm kev thaiv cov teebmeem ntawm progesterone, ua rau ob lub tsev menyuam thiab cov hlab ntsha hauv tsev menyuam. Qhov no ua rau uterine contraction. Mifepristone yog thawj zaug tsim nyob rau hauv 1980 thiab tuaj rau hauv Fabkis xyoo 1987. Nws tau los ua nyob rau hauv Tebchaws Meskas xyoo 2000. Tsis tas li ntawd, cov tshuaj no kuj muaj nyob hauv World He alth lub koom haum cov npe ntawm Cov Tshuaj Tseem Ceeb. Txawm li cas los xij, tus nqi thiab kev muaj txwv tsis pub nkag mus rau mifepristone hauv ntau qhov chaw ntawm cov teb chaws tsim.
Dab tsi zoo sib xws ntawm Misoprostol thiab Mifepristone?
- Misoprostol thiab mifepristone yog ob yam tshuaj uas siv rau kev rho menyuam tawm.
- Lawv siv ua ke.
- Ob yam tshuaj ua rau muaj kev phiv.
- Ob qho tshuaj yog nyob rau hauv daim ntawv hluavtaws.
- Lawv nyob rau hauv lub koom haum World He alth's List of Essential Medicines.
Qhov txawv ntawm Misoprostol thiab Mifepristone yog dab tsi?
Misoprostol yog ib qho hluavtaws prostaglandin siv hauv kev rho menyuam tawm kho mob, thaum mifepristone yog hluavtaws steroid siv hauv kev rho menyuam kho mob. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm misoprostol thiab mifepristone. Tsis tas li ntawd, misoprostol tau tsim nyob rau xyoo 1973, thaum mifepristone tau tsim thawj zaug hauv xyoo 1980.
Cov hauv qab no qhia txog qhov sib txawv ntawm misoprostol thiab mifepristone hauv daim ntawv teev npe rau kev sib piv ntawm ib sab.
Summary – Misoprostol vs Mifepristone
Kev rho menyuam tawm yog ib txoj kev uas siv tshuaj coj los rho menyuam. Misoprostol thiab mifepristone yog ob yam tshuaj siv hauv kev rho menyuam tawm. Misoprostol yog ib qho hluavtaws prostaglandin, thaum mifepristone yog hluavtaws steroid. Yog li, qhov no yog qhov sib txawv tseem ceeb ntawm misoprostol thiab mifepristone.
